JP2023544037A5 - - Google Patents
Info
- Publication number
- JP2023544037A5 JP2023544037A5 JP2023520162A JP2023520162A JP2023544037A5 JP 2023544037 A5 JP2023544037 A5 JP 2023544037A5 JP 2023520162 A JP2023520162 A JP 2023520162A JP 2023520162 A JP2023520162 A JP 2023520162A JP 2023544037 A5 JP2023544037 A5 JP 2023544037A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- product mixture
- reaction product
- approximately
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063087109P | 2020-10-02 | 2020-10-02 | |
| US63/087,109 | 2020-10-02 | ||
| PCT/US2021/053005 WO2022072721A1 (en) | 2020-10-02 | 2021-09-30 | Process for the preparation of biheteroaryl compounds and crystal forms thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023544037A JP2023544037A (ja) | 2023-10-19 |
| JP2023544037A5 true JP2023544037A5 (enExample) | 2024-10-04 |
| JP7805356B2 JP7805356B2 (ja) | 2026-01-23 |
Family
ID=78599176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023520162A Active JP7805356B2 (ja) | 2020-10-02 | 2021-09-30 | ビヘテロアリール化合物およびその結晶形態を調製するための方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20230312473A1 (enExample) |
| EP (1) | EP4222154A1 (enExample) |
| JP (1) | JP7805356B2 (enExample) |
| KR (1) | KR20230079123A (enExample) |
| CN (1) | CN116744933A (enExample) |
| AU (1) | AU2021353532A1 (enExample) |
| BR (1) | BR112023005853A2 (enExample) |
| CA (1) | CA3200566A1 (enExample) |
| CL (3) | CL2023000945A1 (enExample) |
| CR (1) | CR20230183A (enExample) |
| IL (1) | IL301266A (enExample) |
| MX (1) | MX2023003759A (enExample) |
| PE (1) | PE20230781A1 (enExample) |
| SA (1) | SA523440027B1 (enExample) |
| WO (1) | WO2022072721A1 (enExample) |
| ZA (1) | ZA202303449B (enExample) |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| US5004697A (en) | 1987-08-17 | 1991-04-02 | Univ. Of Ca | Cationized antibodies for delivery through the blood-brain barrier |
| US5112596A (en) | 1990-04-23 | 1992-05-12 | Alkermes, Inc. | Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability |
| US5268164A (en) | 1990-04-23 | 1993-12-07 | Alkermes, Inc. | Increasing blood-brain barrier permeability with permeabilizer peptides |
| EP0652775B1 (en) | 1992-07-27 | 2000-04-19 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Targeting of liposomes to the blood-brain barrier |
| US6514221B2 (en) | 2000-07-27 | 2003-02-04 | Brigham And Women's Hospital, Inc. | Blood-brain barrier opening |
| WO2002017930A2 (en) | 2000-08-30 | 2002-03-07 | The Board Of Trustees Of The Leland Stanford Junior University | Glucocorticoid blocking agents for increasing blood-brain barrier permeability |
| US7034036B2 (en) | 2000-10-30 | 2006-04-25 | Pain Therapeutics, Inc. | Inhibitors of ABC drug transporters at the blood-brain barrier |
| DE10121982B4 (de) | 2001-05-05 | 2008-01-24 | Lts Lohmann Therapie-Systeme Ag | Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US20030162695A1 (en) | 2002-02-27 | 2003-08-28 | Schatzberg Alan F. | Glucocorticoid blocking agents for increasing blood-brain barrier permeability |
| AU2003302676A1 (en) | 2002-12-03 | 2004-06-23 | Blanchette Rockefeller Neurosciences Institute | Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier |
| EP1663239A4 (en) | 2003-09-10 | 2008-07-23 | Cedars Sinai Medical Center | KALIUM CHANNEL-MEDIATED FEEDING OF MEDICINES BY THE BLOOD BRAIN BARRIER |
| CN104043126A (zh) | 2009-10-22 | 2014-09-17 | 霍夫曼-拉罗奇有限公司 | 轴突变性的调节 |
| PE20161063A1 (es) * | 2013-05-01 | 2016-10-22 | Hoffmann La Roche | Compuestos de biheteroarilo y usos de los mismos |
-
2021
- 2021-09-30 JP JP2023520162A patent/JP7805356B2/ja active Active
- 2021-09-30 EP EP21806494.7A patent/EP4222154A1/en active Pending
- 2021-09-30 CR CR20230183A patent/CR20230183A/es unknown
- 2021-09-30 MX MX2023003759A patent/MX2023003759A/es unknown
- 2021-09-30 KR KR1020237013971A patent/KR20230079123A/ko not_active Ceased
- 2021-09-30 WO PCT/US2021/053005 patent/WO2022072721A1/en not_active Ceased
- 2021-09-30 AU AU2021353532A patent/AU2021353532A1/en active Pending
- 2021-09-30 CA CA3200566A patent/CA3200566A1/en active Pending
- 2021-09-30 CN CN202180067829.1A patent/CN116744933A/zh active Pending
- 2021-09-30 BR BR112023005853A patent/BR112023005853A2/pt unknown
- 2021-09-30 PE PE2023001333A patent/PE20230781A1/es unknown
- 2021-09-30 IL IL301266A patent/IL301266A/en unknown
-
2023
- 2023-03-09 ZA ZA2023/03449A patent/ZA202303449B/en unknown
- 2023-03-30 CL CL2023000945A patent/CL2023000945A1/es unknown
- 2023-03-31 US US18/194,423 patent/US20230312473A1/en active Pending
- 2023-04-02 SA SA523440027A patent/SA523440027B1/ar unknown
-
2024
- 2024-10-07 CL CL2024003034A patent/CL2024003034A1/es unknown
- 2024-10-07 CL CL2024003032A patent/CL2024003032A1/es unknown
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