JP2023533855A5 - - Google Patents
Info
- Publication number
- JP2023533855A5 JP2023533855A5 JP2023502881A JP2023502881A JP2023533855A5 JP 2023533855 A5 JP2023533855 A5 JP 2023533855A5 JP 2023502881 A JP2023502881 A JP 2023502881A JP 2023502881 A JP2023502881 A JP 2023502881A JP 2023533855 A5 JP2023533855 A5 JP 2023533855A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- formula
- acceptable salt
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063052574P | 2020-07-16 | 2020-07-16 | |
| US202063052561P | 2020-07-16 | 2020-07-16 | |
| US63/052,574 | 2020-07-16 | ||
| US63/052,561 | 2020-07-16 | ||
| PCT/US2021/034599 WO2022015423A1 (en) | 2020-07-16 | 2021-05-27 | ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023533855A JP2023533855A (ja) | 2023-08-04 |
| JP2023533855A5 true JP2023533855A5 (enExample) | 2025-09-12 |
| JP7867482B2 JP7867482B2 (ja) | 2026-05-29 |
Family
ID=79293345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023502881A Active JP7867482B2 (ja) | 2020-07-16 | 2021-05-27 | イソキノリン化合物およびそのＡｈＲ不均衡の治療への使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US11267788B2 (enExample) |
| EP (2) | EP4786453A2 (enExample) |
| JP (1) | JP7867482B2 (enExample) |
| KR (1) | KR20230041021A (enExample) |
| CN (1) | CN116157387B (enExample) |
| AU (1) | AU2021308209A1 (enExample) |
| CA (1) | CA3185793A1 (enExample) |
| IL (1) | IL299756A (enExample) |
| MX (1) | MX2023000263A (enExample) |
| WO (1) | WO2022015423A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11267788B2 (en) | 2020-07-16 | 2022-03-08 | Dermavant Sciences GmbH | Isoquinoline compounds and their use in treating AhR imbalance |
| WO2024020170A1 (en) * | 2022-07-21 | 2024-01-25 | Allianthera (Suzhou) Biopharmaceutical Co., Ltd. | Aryl hydrocarbon receptor agonist prodrugs and methods of use thereof |
| US20260069585A1 (en) * | 2022-08-30 | 2026-03-12 | Dermavant Sciences GmbH | ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR MEDIATED DISEASES |
| WO2024152993A1 (zh) * | 2023-01-17 | 2024-07-25 | 上海泽德曼医药科技有限公司 | 稠环类化合物、其制备方法及其在医药上的应用 |
| CN117447402A (zh) * | 2023-10-18 | 2024-01-26 | 德明药泰生物技术（深圳）有限公司 | 芳香烃受体调节剂类化合物及其制备方法和应用 |
| CN117229208B (zh) * | 2023-11-13 | 2024-02-23 | 上海泽德曼医药科技有限公司 | 稠环类化合物、其制备方法及其在医药上的应用 |
| WO2026083733A1 (ja) * | 2024-10-18 | 2026-04-23 | 株式会社ヤクルト本社 | 試験方法、ゲル状組成物、及び試験装置 |
| WO2026096218A1 (en) * | 2024-10-18 | 2026-05-07 | Dermavant Sciences GmbH | Pharmaceutical compositions for respiratory administration and methods of treating inflammatory diseases of the lungs |
| WO2026085237A1 (en) * | 2024-10-18 | 2026-04-23 | Dermavant Sciences GmbH | Process for preparing 2-isopropyl-5-(isoquinolin-3-yl)benzene-1,3-diol |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06504791A (ja) | 1991-04-10 | 1994-06-02 | オクタマー，インコーポレイティド | レトロウィルス複製の阻害のための方法 |
| US5919970A (en) | 1997-04-24 | 1999-07-06 | Allergan Sales, Inc. | Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity |
| WO1999018077A1 (en) * | 1997-10-02 | 1999-04-15 | Eisai Co., Ltd. | Fused pyridine derivatives |
| DE60233414D1 (de) | 2001-07-09 | 2009-10-01 | Combinatorx Inc | Kombinationen für die behandlung entzündlicher erkrankungen |
| CN1596240A (zh) | 2001-12-19 | 2005-03-16 | 阿特罗吉尼克斯公司 | 查耳酮衍生物及其治疗疾病的用途 |
| WO2003053359A2 (en) | 2001-12-19 | 2003-07-03 | Atherogenics, Inc. | 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders |
| EP1704856A4 (en) | 2003-12-26 | 2009-08-19 | Kyowa Hakko Kirin Co Ltd | PROTEIN INHIBITOR OF THE HSP90 FAMILY |
| WO2006058201A2 (en) | 2004-11-23 | 2006-06-01 | Reddy Us Therapeutics, Inc. | Heterocyclic and bicyclic compounds, compositions and methods |
| GB0704718D0 (en) | 2007-03-12 | 2007-04-18 | Prendergast Patrick T | Compounds and methods for preventing and treating mucositis |
| EP2014651A1 (en) | 2007-07-12 | 2009-01-14 | Exonhit Therapeutics SA | Compounds and methods for modulating Rho GTPases |
| JP5439127B2 (ja) | 2009-11-13 | 2014-03-12 | 株式会社さいわいメディカル | 乾癬又はアトピー性皮膚炎治療剤 |
| US8933096B2 (en) | 2010-06-09 | 2015-01-13 | Rugers, The State University of New Jersey | Antimicrobial agents |
| GB201216017D0 (en) * | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
| KR20150118106A (ko) | 2012-12-20 | 2015-10-21 | 알데이라 테라퓨틱스, 아이엔씨. | 페리-카르비놀 |
| GB201304041D0 (en) | 2013-03-06 | 2013-04-17 | Water Jel Europ Llp | Treatment and prophylaxis of radiation dermatitis |
| JP6899323B2 (ja) | 2014-10-14 | 2021-07-07 | ラ ホーヤ インスティテュート オブ アレルギー アンド イミュノロジー | 低分子量タンパク質チロシンホスファターゼの阻害剤、及びその使用 |
| JP7138654B2 (ja) | 2017-03-29 | 2022-09-16 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 金属錯体 |
| WO2019018562A1 (en) | 2017-07-19 | 2019-01-24 | Ideaya Biosciences, Inc. | AMIDO COMPOUND AS MODULATORS OF AHR |
| CN111699192B (zh) | 2018-02-13 | 2024-03-08 | Udc爱尔兰有限公司 | 金属络合物 |
| TWI828664B (zh) | 2018-03-19 | 2024-01-11 | 愛爾蘭商Ｕｄｃ愛爾蘭責任有限公司 | 金屬錯合物 |
| US11267788B2 (en) | 2020-07-16 | 2022-03-08 | Dermavant Sciences GmbH | Isoquinoline compounds and their use in treating AhR imbalance |
| WO2023020512A1 (zh) * | 2021-08-16 | 2023-02-23 | 成都奥睿药业有限公司 | 取代的吡啶类似物、其制备方法及作为ahr调节剂的用途 |
| CN116947799B (zh) * | 2023-03-08 | 2024-05-03 | 上海泽德曼医药科技有限公司 | 酚类化合物、其制备方法及其在医药上的应用 |
-
2021
- 2021-05-27 US US17/332,805 patent/US11267788B2/en active Active
- 2021-05-27 CN CN202180060054.5A patent/CN116157387B/zh active Active
- 2021-05-27 AU AU2021308209A patent/AU2021308209A1/en active Pending
- 2021-05-27 IL IL299756A patent/IL299756A/en unknown
- 2021-05-27 EP EP26186010.0A patent/EP4786453A2/en active Pending
- 2021-05-27 CA CA3185793A patent/CA3185793A1/en active Pending
- 2021-05-27 KR KR1020237005000A patent/KR20230041021A/ko not_active Ceased
- 2021-05-27 JP JP2023502881A patent/JP7867482B2/ja active Active
- 2021-05-27 MX MX2023000263A patent/MX2023000263A/es unknown
- 2021-05-27 WO PCT/US2021/034599 patent/WO2022015423A1/en not_active Ceased
- 2021-05-27 EP EP21842240.0A patent/EP4185566B1/en active Active
-
2022
- 2022-01-28 US US17/587,812 patent/US11548853B2/en active Active
- 2022-10-28 US US18/050,888 patent/US11827605B2/en active Active
-
2023
- 2023-10-20 US US18/491,538 patent/US12252471B2/en active Active
-
2025
- 2025-02-14 US US19/053,643 patent/US20250282730A1/en active Pending
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