JP2023520201A5 - - Google Patents

Info

Publication number
JP2023520201A5
JP2023520201A5 JP2022559478A JP2022559478A JP2023520201A5 JP 2023520201 A5 JP2023520201 A5 JP 2023520201A5 JP 2022559478 A JP2022559478 A JP 2022559478A JP 2022559478 A JP2022559478 A JP 2022559478A JP 2023520201 A5 JP2023520201 A5 JP 2023520201A5
Authority
JP
Japan
Prior art keywords
group
formula
optionally substituted
ether
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022559478A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023520201A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/052595 external-priority patent/WO2021198883A1/en
Publication of JP2023520201A publication Critical patent/JP2023520201A/ja
Publication of JP2023520201A5 publication Critical patent/JP2023520201A5/ja
Pending legal-status Critical Current

Links

JP2022559478A 2020-03-31 2021-03-30 オリゴヌクレオチド及び関連化合物の合成 Pending JP2023520201A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063003067P 2020-03-31 2020-03-31
US63/003,067 2020-03-31
PCT/IB2021/052595 WO2021198883A1 (en) 2020-03-31 2021-03-30 Synthesis of oligonucleotides and related compounds

Publications (2)

Publication Number Publication Date
JP2023520201A JP2023520201A (ja) 2023-05-16
JP2023520201A5 true JP2023520201A5 (https=) 2024-04-02

Family

ID=75340013

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022559478A Pending JP2023520201A (ja) 2020-03-31 2021-03-30 オリゴヌクレオチド及び関連化合物の合成

Country Status (11)

Country Link
US (1) US20240092821A1 (https=)
EP (1) EP4126894A1 (https=)
JP (1) JP2023520201A (https=)
KR (1) KR20220161436A (https=)
CN (1) CN115843299A (https=)
AU (1) AU2021247043A1 (https=)
BR (1) BR112022019752A2 (https=)
CA (1) CA3178892A1 (https=)
IL (1) IL296862A (https=)
MX (1) MX2022012255A (https=)
WO (1) WO2021198883A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4293035A4 (en) 2021-02-12 2025-03-05 Ajinomoto Co., Inc. METHOD FOR THE PRODUCTION OF OLIGONUCLEOTIDES
EP4601656A1 (en) * 2022-10-12 2025-08-20 Pharmorage Pty Limited Modified oligonucleotides
WO2025028656A1 (ja) 2023-08-02 2025-02-06 日東電工株式会社 オリゴヌクレオチドを製造する方法
WO2025235761A1 (en) * 2024-05-09 2025-11-13 Biogen Ma Inc. Reagents and processes for preparing oligonucleotides

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001704A1 (en) 1990-07-26 1992-02-06 Koichi Shudo Oligodeoxyribonucleotides
US6972330B2 (en) * 1996-02-13 2005-12-06 Sirna Therapeutics, Inc. Chemical synthesis of methoxy nucleosides
US5753789A (en) 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
ES2192672T3 (es) 1996-11-18 2003-10-16 Takeshi Imanishi Nuevos analogos de nucleotidos.
US6770748B2 (en) 1997-03-07 2004-08-03 Takeshi Imanishi Bicyclonucleoside and oligonucleotide analogue
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
US6251666B1 (en) 1997-03-31 2001-06-26 Ribozyme Pharmaceuticals, Inc. Nucleic acid catalysts comprising L-nucleotide analogs
US6794499B2 (en) 1997-09-12 2004-09-21 Exiqon A/S Oligonucleotide analogues
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ/エス オリゴヌクレオチド類似体
ES2234563T5 (es) 1999-02-12 2018-01-17 Daiichi Sankyo Company, Limited Nuevos análogos de nucleósidos y oligonucleótidos
JP2000247940A (ja) * 1999-02-26 2000-09-12 Sankyo Co Ltd 新規ベンジルアジド化合物
US7084125B2 (en) 1999-03-18 2006-08-01 Exiqon A/S Xylo-LNA analogues
US7053207B2 (en) 1999-05-04 2006-05-30 Exiqon A/S L-ribo-LNA analogues
US6525191B1 (en) 1999-05-11 2003-02-25 Kanda S. Ramasamy Conformationally constrained L-nucleosides
JP4151751B2 (ja) 1999-07-22 2008-09-17 第一三共株式会社 新規ビシクロヌクレオシド類縁体
US7569575B2 (en) 2002-05-08 2009-08-04 Santaris Pharma A/S Synthesis of locked nucleic acid derivatives
WO2004041889A2 (en) 2002-11-05 2004-05-21 Isis Pharmaceuticals, Inc. Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
CN101684136A (zh) * 2008-09-23 2010-03-31 苏州瑞博生物技术有限公司 一种寡核苷酸的制备方法
US9284344B2 (en) 2012-05-30 2016-03-15 Hokkaido System Science Co., Ltd. Oligonucleotide synthesis method using highly dispersible liquid-phase support
US10214555B2 (en) 2012-11-14 2019-02-26 Takeda Pharmaceutical Company Limitjed Method for liquid-phase synthesis of nucleic acid
CN116063365A (zh) 2015-12-16 2023-05-05 味之素株式会社 寡核苷酸的制备方法以及核苷、核苷酸或寡核苷酸
WO2017111137A1 (ja) 2015-12-22 2017-06-29 味の素株式会社 オリゴヌクレオチドの製造方法
TW201906855A (zh) 2017-05-02 2019-02-16 日商日產化學工業股份有限公司 寡核苷酸之製造方法

Similar Documents

Publication Publication Date Title
JP2023520201A5 (https=)
JP2005505565A5 (https=)
EP1956028B1 (en) Photolabile compound, oligomer probe array and substrate for oligomer probe array containing the same, and manufacturing method of the same
JP2005532287A5 (https=)
TWI660962B (zh) 矽氮烷化合物的製造方法
JP5407825B2 (ja) 2以上のアミノ基を有するシラン化合物及びその製造方法
JP2002522446A5 (https=)
WO2005028494A1 (ja) 5'-ホスフィチル化モノマーおよびh-ホスホネートオリゴヌクレオチド誘導体の製造方法
JP2023539390A5 (https=)
JP2013505333A5 (https=)
JP2023507403A5 (https=)
JPWO2020235658A5 (https=)
JP2002128790A (ja) 有機ケイ素化合物
JP2021503522A5 (https=)
JP6052140B2 (ja) ビスシリルアミノ基を有するオルガノキシシラン化合物及びその製造方法
US12371451B2 (en) Inorganic porous carrier and method for producing nucleic acids using same
IL77298A (en) Process for preparing 2-(alkanoyloxymethoxy)-1, 3-propanediols esters and ehers thereof their use in the preparation of (9H-guaninemethoxy)-1, 3-propanediol-derivatives and some new esters and ethers of 2-(alkanoyloxymethoxy)-1, 3-propanediols
JP2732989B2 (ja) ポリオキサゾリン変性シランおよびその製造方法
JP2007522151A5 (https=)
US4882448A (en) Si,Si'diorganyl-N-alkyl-tetrachloro-disilazanes and a process for their preparation
CN103497215B (zh) 用于免疫佐剂E6020之合成前体的β-酮酰胺合成的试剂和方法
JP6720913B2 (ja) 不飽和結合含有ビスシリル化合物およびその製造方法
JP5929837B2 (ja) シリル基で保護された含窒素環状化合物及びその製造方法
JP2008514728A5 (https=)
JP2701102B2 (ja) 有機ケイ素化合物