JP2023520201A5 - - Google Patents
Info
- Publication number
- JP2023520201A5 JP2023520201A5 JP2022559478A JP2022559478A JP2023520201A5 JP 2023520201 A5 JP2023520201 A5 JP 2023520201A5 JP 2022559478 A JP2022559478 A JP 2022559478A JP 2022559478 A JP2022559478 A JP 2022559478A JP 2023520201 A5 JP2023520201 A5 JP 2023520201A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- optionally substituted
- ether
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063003067P | 2020-03-31 | 2020-03-31 | |
| US63/003,067 | 2020-03-31 | ||
| PCT/IB2021/052595 WO2021198883A1 (en) | 2020-03-31 | 2021-03-30 | Synthesis of oligonucleotides and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023520201A JP2023520201A (ja) | 2023-05-16 |
| JP2023520201A5 true JP2023520201A5 (enExample) | 2024-04-02 |
Family
ID=75340013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022559478A Pending JP2023520201A (ja) | 2020-03-31 | 2021-03-30 | オリゴヌクレオチド及び関連化合物の合成 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12649761B2 (enExample) |
| EP (1) | EP4126894A1 (enExample) |
| JP (1) | JP2023520201A (enExample) |
| KR (1) | KR20220161436A (enExample) |
| CN (1) | CN115843299A (enExample) |
| AU (1) | AU2021247043A1 (enExample) |
| BR (1) | BR112022019752A2 (enExample) |
| CA (1) | CA3178892A1 (enExample) |
| IL (1) | IL296862A (enExample) |
| MX (1) | MX2022012255A (enExample) |
| WO (1) | WO2021198883A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12649761B2 (en) | 2020-03-31 | 2026-06-09 | Janssen Biopharma, Inc. | Synthesis of oligonucleotides and related compounds |
| CN116888136A (zh) | 2021-02-12 | 2023-10-13 | 味之素株式会社 | 寡核苷酸的制备方法 |
| EP4601656A1 (en) * | 2022-10-12 | 2025-08-20 | Pharmorage Pty Limited | Modified oligonucleotides |
| EP4755898A1 (en) | 2023-08-02 | 2026-06-10 | Nitto Denko Corporation | Method for producing oligonucleotide |
| WO2025235761A1 (en) * | 2024-05-09 | 2025-11-13 | Biogen Ma Inc. | Reagents and processes for preparing oligonucleotides |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992001704A1 (en) | 1990-07-26 | 1992-02-06 | Koichi Shudo | Oligodeoxyribonucleotides |
| US6972330B2 (en) * | 1996-02-13 | 2005-12-06 | Sirna Therapeutics, Inc. | Chemical synthesis of methoxy nucleosides |
| US5753789A (en) | 1996-07-26 | 1998-05-19 | Yale University | Oligonucleotides containing L-nucleosides |
| ES2192672T3 (es) | 1996-11-18 | 2003-10-16 | Takeshi Imanishi | Nuevos analogos de nucleotidos. |
| US6770748B2 (en) | 1997-03-07 | 2004-08-03 | Takeshi Imanishi | Bicyclonucleoside and oligonucleotide analogue |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US6251666B1 (en) | 1997-03-31 | 2001-06-26 | Ribozyme Pharmaceuticals, Inc. | Nucleic acid catalysts comprising L-nucleotide analogs |
| US6794499B2 (en) | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
| EP1015469B2 (en) | 1997-09-12 | 2015-11-18 | Exiqon A/S | Bi- and tri-cyclic nucleoside, nucleotide and oligonucleoide analogues |
| BRPI0008131B8 (pt) | 1999-02-12 | 2021-05-25 | Daiichi Sankyo Co Ltd | composto ou um sal deste, análogo de oligonucleotídeo, composição farmacêutica, sonda para um gene,iniciador para começar a amplificação, uso de um análogo de oligonucleotídeo ou de um sal deste farmacologicamente aceitável, agente antisentido, e, agente antígeno |
| JP2000247940A (ja) * | 1999-02-26 | 2000-09-12 | Sankyo Co Ltd | 新規ベンジルアジド化合物 |
| US7084125B2 (en) | 1999-03-18 | 2006-08-01 | Exiqon A/S | Xylo-LNA analogues |
| ATE356824T1 (de) | 1999-05-04 | 2007-04-15 | Santaris Pharma As | L-ribo-lna analoge |
| US6525191B1 (en) | 1999-05-11 | 2003-02-25 | Kanda S. Ramasamy | Conformationally constrained L-nucleosides |
| JP4151751B2 (ja) | 1999-07-22 | 2008-09-17 | 第一三共株式会社 | 新規ビシクロヌクレオシド類縁体 |
| US7569575B2 (en) | 2002-05-08 | 2009-08-04 | Santaris Pharma A/S | Synthesis of locked nucleic acid derivatives |
| CA2504694C (en) | 2002-11-05 | 2013-10-01 | Isis Pharmaceuticals, Inc. | Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation |
| CN101684136A (zh) * | 2008-09-23 | 2010-03-31 | 苏州瑞博生物技术有限公司 | 一种寡核苷酸的制备方法 |
| WO2013179412A1 (ja) | 2012-05-30 | 2013-12-05 | 北海道システム・サイエンス株式会社 | 高分散性液相支持体を用いたオリゴヌクレオチド合成法 |
| US10214555B2 (en) | 2012-11-14 | 2019-02-26 | Takeda Pharmaceutical Company Limitjed | Method for liquid-phase synthesis of nucleic acid |
| EP3398955B1 (en) | 2015-12-16 | 2026-06-03 | Ajinomoto Co., Inc. | Oligonucleotide production method, and nucleoside, nucleotide, or oligonucleotide |
| JPWO2017111137A1 (ja) | 2015-12-22 | 2018-10-18 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| JP7306263B2 (ja) | 2017-05-02 | 2023-07-11 | 日産化学株式会社 | オリゴヌクレオチドの製造方法 |
| US12649761B2 (en) | 2020-03-31 | 2026-06-09 | Janssen Biopharma, Inc. | Synthesis of oligonucleotides and related compounds |
-
2021
- 2021-03-30 US US17/916,064 patent/US12649761B2/en active Active
- 2021-03-30 CN CN202180039628.0A patent/CN115843299A/zh active Pending
- 2021-03-30 KR KR1020227037806A patent/KR20220161436A/ko active Pending
- 2021-03-30 BR BR112022019752A patent/BR112022019752A2/pt not_active IP Right Cessation
- 2021-03-30 CA CA3178892A patent/CA3178892A1/en active Pending
- 2021-03-30 WO PCT/IB2021/052595 patent/WO2021198883A1/en not_active Ceased
- 2021-03-30 MX MX2022012255A patent/MX2022012255A/es unknown
- 2021-03-30 IL IL296862A patent/IL296862A/en unknown
- 2021-03-30 EP EP21715980.5A patent/EP4126894A1/en active Pending
- 2021-03-30 JP JP2022559478A patent/JP2023520201A/ja active Pending
- 2021-03-30 AU AU2021247043A patent/AU2021247043A1/en not_active Abandoned
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