|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
DK1621554T4
(da)
|
1992-08-21 |
2012-12-17 |
Univ Bruxelles |
Immunoglobuliner blottet for lette kæder
|
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
|
ES2162863T3
(es)
|
1993-04-29 |
2002-01-16 |
Unilever Nv |
Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
US6001329A
(en)
|
1996-05-06 |
1999-12-14 |
Uab Research Foundation |
Radiolabeled fusion toxins for cancer therapy
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
US6995259B1
(en)
|
1998-10-23 |
2006-02-07 |
Sirna Therapeutics, Inc. |
Method for the chemical synthesis of oligonucleotides
|
|
US7723111B2
(en)
|
2001-03-09 |
2010-05-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Activated dual specificity lymphocytes and their methods of use
|
|
US7070995B2
(en)
|
2001-04-11 |
2006-07-04 |
City Of Hope |
CE7-specific redirected immune cells
|
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
US8034334B2
(en)
|
2002-09-06 |
2011-10-11 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy
|
|
TW200423951A
(en)
|
2002-11-13 |
2004-11-16 |
Ming-Chung Wong |
Method of preparing anti-angiogenic drug from cartilage and chondrocytes and methods of use
|
|
US20130266551A1
(en)
|
2003-11-05 |
2013-10-10 |
St. Jude Children's Research Hospital, Inc. |
Chimeric receptors with 4-1bb stimulatory signaling domain
|
|
US20070036773A1
(en)
|
2005-08-09 |
2007-02-15 |
City Of Hope |
Generation and application of universal T cells for B-ALL
|
|
CA2651174A1
(en)
|
2006-05-03 |
2007-11-15 |
Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services |
Chimeric t cell receptors and related materials and methods of use
|
|
DE102006031054B4
(de)
|
2006-07-05 |
2010-08-05 |
Hänel & Co. |
Hochregal mit Lagergutanwahl
|
|
US9334330B2
(en)
|
2006-10-10 |
2016-05-10 |
Universite De Nantes |
Use of monoclonal antibodies specific to the O-acetylated form of GD2 ganglioside for the treatment of certain cancers
|
|
WO2008089053A2
(en)
|
2007-01-12 |
2008-07-24 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Gp100-specific t cell receptors and related materials and methods of use
|
|
SI2856876T1
(en)
|
2007-03-30 |
2018-04-30 |
Memorial Sloan-Kettering Cancer Center |
Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes
|
|
US20110213288A1
(en)
|
2007-04-23 |
2011-09-01 |
The Board Of Regents, The University Of Texas System |
Device And Method For Transfecting Cells For Therapeutic Uses
|
|
WO2008131445A1
(en)
|
2007-04-23 |
2008-10-30 |
The Board Of Regents, The University Of Texas System |
Device and method for transfecting cells for therapeutic use
|
|
CA2700278A1
(en)
|
2007-09-25 |
2009-04-02 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Modified t cell receptors and related materials and methods
|
|
CN101335956B
(zh)
|
2008-08-05 |
2011-10-05 |
国民技术股份有限公司 |
借助误码率统计数据判断通信距离的系统和方法
|
|
EP2169837B1
(en)
|
2008-09-29 |
2013-01-30 |
Telefonaktiebolaget LM Ericsson (publ) |
Technique for suppressing noise in a transmitter device
|
|
US20100322909A1
(en)
|
2009-06-17 |
2010-12-23 |
The University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Th1-associated micrornas and their use for tumor immunotherapy
|
|
CA2776143A1
(en)
|
2009-10-01 |
2011-04-07 |
The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services |
Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
|
|
DK2495243T3
(en)
|
2009-10-27 |
2017-03-27 |
Delta-Fly Pharma Inc |
NEW 5-FLUOROURACIL DERIVATE
|
|
WO2011059836A2
(en)
|
2009-10-29 |
2011-05-19 |
Trustees Of Dartmouth College |
T cell receptor-deficient t cell compositions
|
|
US9273283B2
(en)
|
2009-10-29 |
2016-03-01 |
The Trustees Of Dartmouth College |
Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
|
|
US20110104128A1
(en)
|
2009-10-30 |
2011-05-05 |
The Board Of Regents, The University Of Texas System |
Device and Method for Transfecting Cells for Therapeutic Use
|
|
TR201904484T4
(tr)
|
2009-11-03 |
2019-05-21 |
Hope City |
Transdüse T hücre seçimine yönelik kesik epiderimal büyüme faktörü reseptörü (EGFRt).
|
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
|
WO2011150420A1
(en)
|
2010-05-28 |
2011-12-01 |
Baylor College Of Medicine |
Modified gold nanoparticles for therapy
|
|
EP3323830B1
(en)
|
2010-06-19 |
2023-08-23 |
Memorial Sloan-Kettering Cancer Center |
Anti-gd2 antibodies
|
|
AU2011281062B2
(en)
|
2010-07-21 |
2015-01-22 |
Board Of Regents, The University Of Texas System |
Methods and compositions for modification of a HLA locus
|
|
US9163258B2
(en)
|
2010-07-23 |
2015-10-20 |
Fred Hutchinson Cancer Research Center |
Method for the treatment of obesity
|
|
EP2598063A1
(en)
|
2010-07-28 |
2013-06-05 |
Synthes GmbH |
System or bone fixation using biodegradable screw having radial cutouts
|
|
WO2012136231A1
(en)
|
2010-09-08 |
2012-10-11 |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus |
Interleukin 15 as selectable marker for gene transfer in lymphocytes
|
|
CN103124740B
(zh)
|
2010-09-21 |
2015-09-02 |
美国卫生和人力服务部 |
抗-ssx-2t细胞受体和相关材料及使用方法
|
|
WO2012044999A2
(en)
*
|
2010-10-01 |
2012-04-05 |
Ludwig Institute For Cancer Research Ltd. |
Reversible protein multimers, methods for their production and use
|
|
MX2013004792A
(es)
|
2010-10-27 |
2013-08-27 |
Baylor College Medicine |
Receptor cd27 quimericos para redirigir celulas t a malignidades cd70-positivas.
|
|
WO2012071420A1
(en)
|
2010-11-23 |
2012-05-31 |
The Trustees Of Columbia University In The City Of New York |
Enzyme combinations to reduce brain tissue swelling
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
US9233125B2
(en)
|
2010-12-14 |
2016-01-12 |
University Of Maryland, Baltimore |
Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
|
|
KR101796322B1
(ko)
|
2011-01-07 |
2017-12-01 |
삼성전자주식회사 |
항법 알고리즘을 이용한 위치 정보 검출 장치 및 방법
|
|
KR20140004174A
(ko)
|
2011-01-18 |
2014-01-10 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
암 치료를 위한 조성물 및 방법
|
|
EP2673300B1
(en)
|
2011-02-11 |
2016-08-24 |
Memorial Sloan-Kettering Cancer Center |
Hla-restricted, peptide-specific antigen binding proteins
|
|
WO2012148552A2
(en)
|
2011-02-24 |
2012-11-01 |
The Research Foundation Of State University Of New York |
Rectifying electromagnetic nanosensors
|
|
US9987308B2
(en)
|
2011-03-23 |
2018-06-05 |
Fred Hutchinson Cancer Research Center |
Method and compositions for cellular immunotherapy
|
|
US20130071414A1
(en)
|
2011-04-27 |
2013-03-21 |
Gianpietro Dotti |
Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies
|
|
GB201108236D0
(en)
|
2011-05-17 |
2011-06-29 |
Ucl Business Plc |
Method
|
|
MX2014001222A
(es)
|
2011-07-29 |
2014-09-15 |
Univ Pennsylvania |
Receptores coestimuladores de cambio.
|
|
WO2013033626A2
(en)
|
2011-08-31 |
2013-03-07 |
Trustees Of Dartmouth College |
Nkp30 receptor targeted therapeutics
|
|
AU2012309830B2
(en)
|
2011-09-15 |
2017-03-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors recognizing HLA-A1- or HLA-Cw7-restricted mage
|
|
EP3326467B1
(en)
|
2011-09-16 |
2020-03-11 |
Baylor College of Medicine |
Targeting the tumor microenvironment using manipulated nkt cells
|
|
WO2013051718A1
(ja)
|
2011-10-07 |
2013-04-11 |
国立大学法人三重大学 |
キメラ抗原受容体
|
|
ES2654060T3
(es)
|
2011-10-20 |
2018-02-12 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Receptores de antígenos quiméricos anti-CD22
|
|
US9688740B2
(en)
|
2011-10-26 |
2017-06-27 |
National Cancer Center |
Mutant CTLA4 gene transfected T cell and composition including same for anticancer immunotherapy
|
|
US9272002B2
(en)
|
2011-10-28 |
2016-03-01 |
The Trustees Of The University Of Pennsylvania |
Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
|
US9422351B2
(en)
|
2011-11-03 |
2016-08-23 |
The Trustees Of The University Of Pennsylvania |
Isolated B7-H4 specific compositions and methods of use thereof
|
|
WO2013070468A1
(en)
|
2011-11-08 |
2013-05-16 |
The Trustees Of The University Of Pennsylvania |
Glypican-3-specific antibody and uses thereof
|
|
CN104080797A
(zh)
|
2011-11-11 |
2014-10-01 |
弗雷德哈钦森癌症研究中心 |
针对癌症的靶向细胞周期蛋白a1的t细胞免疫疗法
|
|
US10391126B2
(en)
|
2011-11-18 |
2019-08-27 |
Board Of Regents, The University Of Texas System |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA
|
|
US8772058B2
(en)
|
2012-02-02 |
2014-07-08 |
Harris Corporation |
Method for making a redistributed wafer using transferrable redistribution layers
|
|
WO2013121960A1
(ja)
|
2012-02-13 |
2013-08-22 |
電気化学工業株式会社 |
クロロプレンゴム組成物、該クロロプレンゴム組成物を用いた接着剤組成物
|
|
WO2013126729A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Use of the cd2 signaling domain in second-generation chimeric antigen receptors
|
|
CA3285826A1
(en)
|
2012-02-22 |
2026-03-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer
|
|
EP2817330B1
(en)
|
2012-02-22 |
2020-07-08 |
The Trustees of the University of Pennsylvania |
Use of icos-based cars to enhance antitumor activity and car persistence
|
|
RU2766608C2
(ru)
|
2012-04-11 |
2022-03-15 |
Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез |
Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток
|
|
GB201206559D0
(en)
|
2012-04-13 |
2012-05-30 |
Ucl Business Plc |
Polypeptide
|
|
US20130280220A1
(en)
|
2012-04-20 |
2013-10-24 |
Nabil Ahmed |
Chimeric antigen receptor for bispecific activation and targeting of t lymphocytes
|
|
WO2013169691A1
(en)
|
2012-05-07 |
2013-11-14 |
Trustees Of Dartmouth College |
Anti-b7-h6 antibody, fusion proteins, and methods of using the same
|
|
BR112014029417B1
(pt)
|
2012-05-25 |
2023-03-07 |
Cellectis |
Método ex vivo para a preparação de células t para imunoterapia
|
|
US20150017136A1
(en)
|
2013-07-15 |
2015-01-15 |
Cellectis |
Methods for engineering allogeneic and highly active t cell for immunotherapy
|
|
JP2015524255A
(ja)
|
2012-07-13 |
2015-08-24 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
二重特異性抗体を共導入することによってcart細胞の活性を強化する方法
|
|
JP6482461B2
(ja)
|
2012-07-13 |
2019-03-13 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
投与に関する形質導入t細胞の適合性の評価方法
|
|
JP5822798B2
(ja)
|
2012-08-08 |
2015-11-24 |
三菱電機株式会社 |
断熱箱体及びこの断熱箱体を備えた冷蔵庫
|
|
US20140065629A1
(en)
|
2012-08-29 |
2014-03-06 |
Israel Barken |
Methods of treating diseases
|
|
WO2014039513A2
(en)
|
2012-09-04 |
2014-03-13 |
The Trustees Of The University Of Pennsylvania |
Inhibition of diacylglycerol kinase to augment adoptive t cell transfer
|
|
WO2014037422A1
(en)
|
2012-09-04 |
2014-03-13 |
Inven2 As |
Selective and controlled expansion of educated nk cells
|
|
EP2893566B1
(fr)
|
2012-09-05 |
2016-05-18 |
Institut National des Sciences Appliquées de Lyon |
Procede de fabrication d'un transistor a effet de champ a jonction jfet
|
|
WO2014055442A2
(en)
|
2012-10-01 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for targeting stromal cells for the treatment of cancer
|
|
WO2014055771A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
|
AU2013329186B2
(en)
|
2012-10-10 |
2019-02-14 |
Sangamo Therapeutics, Inc. |
T cell modifying compounds and uses thereof
|
|
WO2014059248A1
(en)
|
2012-10-12 |
2014-04-17 |
Philadelphia Health & Education Corporation D/B/A/ Drexel |
Mir-155 enhancement of cd8+ t cell immunity
|
|
JO3529B1
(ar)
|
2013-02-08 |
2020-07-05 |
Amgen Res Munich Gmbh |
مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد
|
|
JP6647868B2
(ja)
|
2013-02-20 |
2020-02-14 |
ノバルティス アーゲー |
ヒト化抗EGFRvIIIキメラ抗原受容体を用いたがんの処置
|
|
US9573988B2
(en)
|
2013-02-20 |
2017-02-21 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
|
|
US9499855B2
(en)
|
2013-03-14 |
2016-11-22 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US20140274801A1
(en)
|
2013-03-14 |
2014-09-18 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified t cells
|
|
US9587237B2
(en)
|
2013-03-14 |
2017-03-07 |
Elwha Llc |
Compositions, methods, and computer systems related to making and administering modified T cells
|
|
US9446105B2
(en)
|
2013-03-15 |
2016-09-20 |
The Trustees Of The University Of Pennsylvania |
Chimeric antigen receptor specific for folate receptor β
|
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
|
US9393268B2
(en)
|
2013-03-15 |
2016-07-19 |
Thomas Jefferson University |
Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same
|
|
WO2014145252A2
(en)
|
2013-03-15 |
2014-09-18 |
Milone Michael C |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
DK2986311T3
(en)
|
2013-04-18 |
2019-02-25 |
Tilt Biotherapeutics Oy |
IMPROVED ADOPTIVE CELL THERAPY
|
|
US20150017120A1
(en)
|
2013-06-13 |
2015-01-15 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-pk il-2 and adoptive cell therapy
|
|
EP3008092A4
(en)
|
2013-06-14 |
2017-01-11 |
The University Of Houston System |
Targeting tumor neovasculature with modified chimeric antigen receptors
|
|
DE102013212604A1
(de)
|
2013-06-28 |
2014-12-31 |
Robert Bosch Gmbh |
Bearbeitungswerkzeug
|
|
WO2015010096A1
(en)
|
2013-07-18 |
2015-01-22 |
Baylor College Of Medicine |
Method of enhancing potency of immune cells
|
|
NO335489B1
(no)
|
2013-08-27 |
2014-12-22 |
Langåker John Magne |
Multifunksjons varmepumpe
|
|
WO2015031624A1
(en)
|
2013-08-30 |
2015-03-05 |
Hubbell Incorporated |
Wifi hazardous area voip paging telephone and system
|
|
WO2015038684A1
(en)
|
2013-09-10 |
2015-03-19 |
Polyera Corporation |
Attachable article with signaling, split display and messaging features
|
|
WO2015118208A1
(en)
|
2014-02-05 |
2015-08-13 |
Elcogen Oy |
Assembly method and arrangement for a cell system
|
|
US9926405B2
(en)
|
2014-03-17 |
2018-03-27 |
Namics Corporation |
Resin composition
|
|
TWI751102B
(zh)
|
2014-08-28 |
2022-01-01 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
MX392487B
(es)
|
2014-10-20 |
2025-03-21 |
Juno Therapeutics Inc |
Métodos y composiciones para dosificación en terapia celular adoptiva.
|
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
|
ES2818103T3
(es)
|
2015-01-16 |
2021-04-09 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígenos quiméricos específicos para ROR1
|
|
AU2016249005B2
(en)
|
2015-04-17 |
2022-06-16 |
Novartis Ag |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
CA2992551A1
(en)
|
2015-07-21 |
2017-01-26 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
WO2017112877A1
(en)
*
|
2015-12-22 |
2017-06-29 |
Icell Gene Therapeutics, Llc |
Chimeric antigen receptors and enhancement of anti-tumor activity
|
|
KR102746901B1
(ko)
*
|
2017-03-03 |
2024-12-26 |
옵시디안 테라퓨틱스, 인크. |
Cd19 조성물 및 면역요법을 위한 방법
|
|
WO2019004831A1
(en)
*
|
2017-06-30 |
2019-01-03 |
Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) |
TREATMENT OF HEMATOLOGICAL MALIGNANCIES
|
|
US20210147550A1
(en)
*
|
2017-08-18 |
2021-05-20 |
Joshua Michael Francis |
Antigen-binding proteins targeting shared antigens
|
|
US11957715B2
(en)
*
|
2017-12-20 |
2024-04-16 |
Miltenyi Biotec B.V. & Co. KG |
Method for NK cell transduction
|