JP2023516640A5 - - Google Patents
Info
- Publication number
- JP2023516640A5 JP2023516640A5 JP2022552324A JP2022552324A JP2023516640A5 JP 2023516640 A5 JP2023516640 A5 JP 2023516640A5 JP 2022552324 A JP2022552324 A JP 2022552324A JP 2022552324 A JP2022552324 A JP 2022552324A JP 2023516640 A5 JP2023516640 A5 JP 2023516640A5
- Authority
- JP
- Japan
- Prior art keywords
- lung
- crystalline hydrate
- pharmaceutical composition
- transplant rejection
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062983931P | 2020-03-02 | 2020-03-02 | |
| US62/983,931 | 2020-03-02 | ||
| PCT/US2021/070207 WO2021178991A1 (en) | 2020-03-02 | 2021-03-01 | Crystalline hydrate of a jak inhibitor compound |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023516640A JP2023516640A (ja) | 2023-04-20 |
| JP2023516640A5 true JP2023516640A5 (enExample) | 2024-02-14 |
| JP7681613B2 JP7681613B2 (ja) | 2025-05-22 |
Family
ID=75143791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552324A Active JP7681613B2 (ja) | 2020-03-02 | 2021-03-01 | Ｊａｋ阻害剤化合物の結晶性水和物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11702415B2 (enExample) |
| EP (1) | EP4114836B1 (enExample) |
| JP (1) | JP7681613B2 (enExample) |
| KR (1) | KR20220149585A (enExample) |
| CN (1) | CN115190878B (enExample) |
| AR (1) | AR121483A1 (enExample) |
| AU (1) | AU2021232100A1 (enExample) |
| BR (1) | BR112022017398A2 (enExample) |
| CA (1) | CA3172338A1 (enExample) |
| CL (1) | CL2022002368A1 (enExample) |
| CO (1) | CO2022012476A2 (enExample) |
| IL (1) | IL295613A (enExample) |
| MX (1) | MX2022010795A (enExample) |
| PH (1) | PH12022552261A1 (enExample) |
| WO (1) | WO2021178991A1 (enExample) |
| ZA (1) | ZA202209617B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3837258T3 (da) * | 2018-09-04 | 2024-07-22 | Theravance Biopharma R&D Ip Llc | Dimethyl amino azetidine amides as jak inhibitors |
| KR20220149585A (ko) * | 2020-03-02 | 2022-11-08 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 억제제 화합물의 결정성 수화물 |
| WO2022119535A1 (en) * | 2020-12-04 | 2022-06-09 | Centurion Ilac Sanayi Ve Ticaret Anonim Sirketi | New dosage regimen for inhaled vasoactive intestinal polypeptide |
| WO2023230236A1 (en) | 2022-05-26 | 2023-11-30 | Theravance Biopharma R&D Ip, Llc | Process for preparing jak inhibitors and intermediates thereof |
| CN116785290B (zh) * | 2023-02-01 | 2024-02-13 | 银谷制药有限责任公司 | 苯环喹溴铵及其异构体在制备眼用制剂中的应用 |
| KR20260019479A (ko) | 2023-05-04 | 2026-02-10 | 레볼루션 메디슨즈, 인크. | Ras 관련 질환 또는 장애를 위한 병용 요법 |
| CN121889155A (zh) | 2023-08-07 | 2026-04-17 | 锐新医药公司 | 用于治疗ras蛋白相关疾病或病症的rmc-6291 |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| WO2026090116A2 (en) | 2024-10-21 | 2026-04-30 | Revolution Medicines, Inc. | Ras inhibitors |
| US20260108528A1 (en) | 2024-10-22 | 2026-04-23 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2026090245A1 (en) | 2024-10-22 | 2026-04-30 | Revolution Medicines, Inc. | Use of ras inhibitors for treating cancer |
| WO2026106912A1 (en) | 2024-11-12 | 2026-05-21 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026112260A1 (en) | 2024-11-21 | 2026-05-28 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026122764A2 (en) | 2024-12-06 | 2026-06-11 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026128688A2 (en) | 2024-12-13 | 2026-06-18 | Revolution Medicines, Inc. | Ras inhibitors |
| CN119438457B (zh) * | 2024-12-18 | 2025-12-02 | 成都迈科康生物科技有限公司 | 一种测定脂质体佐剂中有关物质的方法及其应用 |
| WO2026161839A1 (en) | 2025-01-27 | 2026-07-30 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI262914B (en) | 1999-07-02 | 2006-10-01 | Agouron Pharma | Compounds and pharmaceutical compositions for inhibiting protein kinases |
| US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| US20050090529A1 (en) | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| US7884109B2 (en) | 2005-04-05 | 2011-02-08 | Wyeth Llc | Purine and imidazopyridine derivatives for immunosuppression |
| US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| JP2010111624A (ja) | 2008-11-06 | 2010-05-20 | Shionogi & Co Ltd | Ｔｔｋ阻害作用を有するインダゾール誘導体 |
| CA2756989A1 (en) | 2009-04-03 | 2010-10-07 | Douglas Burdi | Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof |
| SMT201700581T1 (it) | 2009-12-21 | 2018-01-11 | Samumed Llc | 1h-pirazolo[3,4-b]piridine e loro usi terapeutici |
| US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| LT3077395T (lt) | 2013-12-05 | 2018-02-12 | Pfizer Inc. | Pirolo[2,3-d]pirimidinilo, pirolo[2,3-b]pirazinilo ir pirolo[2,3-d]piridinilo akrilamidai |
| PE20161475A1 (es) | 2014-05-14 | 2017-01-08 | Pfizer | Pirazolopiridinas y pirazolopirimidinas |
| WO2016026078A1 (en) | 2014-08-19 | 2016-02-25 | Changzhou Jiekai Pharmatech Co., Ltd. | Heterocyclic compounds as erk inhibitors |
| KR101663277B1 (ko) | 2015-03-30 | 2016-10-06 | 주식회사 녹십자 | TNIK, IKKε 및 TBK1 억제제로서의 피라졸계 유도체 및 이를 포함하는 약학적 조성물 |
| EP3831830A1 (en) | 2015-11-03 | 2021-06-09 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors |
| TWI710560B (zh) | 2015-11-03 | 2020-11-21 | 美商施萬生物製藥研發Ｉｐ有限責任公司 | 用於治療呼吸疾病之jak激酶抑制劑化合物 |
| DK3712152T3 (da) | 2015-11-03 | 2021-03-22 | Topivert Pharma Ltd | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridin og 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepinderivater som janus kinase-inhibitorer |
| TWI754019B (zh) | 2017-03-09 | 2022-02-01 | 美商施萬生物製藥研發 Ip有限責任公司 | 含有4員雜環醯胺之jak抑制劑 |
| US20180258546A1 (en) | 2017-03-09 | 2018-09-13 | Lam Research Corporation | Electroplating apparatus and methods utilizing independent control of impinging electrolyte |
| EP3619208B1 (en) | 2017-05-01 | 2023-06-07 | Theravance Biopharma R&D IP, LLC | Crystalline forms of a jak inhibitor compound |
| AU2018261588A1 (en) | 2017-05-01 | 2019-10-31 | Theravance Biopharma R&D Ip, Llc | Methods of treatment using a JAK inhibitor compound |
| AR111495A1 (es) | 2017-05-01 | 2019-07-17 | Theravance Biopharma R&D Ip Llc | Compuestos de imidazo-piperidina fusionada como inhibidores de jak |
| BR112021004087A2 (pt) | 2018-09-04 | 2021-05-25 | Theravance Biopharma R&D Ip, Llc | processo para preparar inibidores de jak e seus intermediários |
| DK3837258T3 (da) | 2018-09-04 | 2024-07-22 | Theravance Biopharma R&D Ip Llc | Dimethyl amino azetidine amides as jak inhibitors |
| BR112021004063A2 (pt) | 2018-09-04 | 2021-05-25 | Theravance Biopharma R&D Ip, Llc | amidas heterocíclicas com 5 a 7 membros como inibidores de jak |
| EP3853229A1 (en) | 2018-10-29 | 2021-07-28 | Theravance Biopharma R&D IP, LLC | 2-azabicyclo hexane compound as jak inhibitor |
| KR102873783B1 (ko) | 2019-02-25 | 2025-10-21 | 메디노 파마슈티컬 테크놀로지 (주하이) 컴퍼니 리미티드 | Jak 억제제 화합물 및 그 사용 |
| UA130579C2 (uk) | 2019-03-05 | 2026-03-25 | Інсайт Корпорейшн | Інгібітори шляхів jak1 для лікування хронічної дисфункції алотрансплантата легень |
| CN112279848A (zh) | 2019-07-25 | 2021-01-29 | 四川海思科制药有限公司 | 一种泛JAKs抑制剂及其用途 |
| KR20220149585A (ko) * | 2020-03-02 | 2022-11-08 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 억제제 화합물의 결정성 수화물 |
| TW202207921A (zh) | 2020-05-08 | 2022-03-01 | 美商施萬生物製藥研發Ｉｐ有限責任公司 | 以二甲基胺基吖呾醯胺化合物治療受冠狀病毒感染的患者之方法 |
| WO2022271604A1 (en) | 2021-06-21 | 2022-12-29 | Theravance Biopharma R&D Ip, Llc | Method of treating a patient infected with a coronavirus and having a baseline level of crp below 150 mg/l |
-
2021
- 2021-03-01 KR KR1020227034088A patent/KR20220149585A/ko active Pending
- 2021-03-01 AU AU2021232100A patent/AU2021232100A1/en not_active Abandoned
- 2021-03-01 EP EP21713868.4A patent/EP4114836B1/en active Active
- 2021-03-01 PH PH1/2022/552261A patent/PH12022552261A1/en unknown
- 2021-03-01 WO PCT/US2021/070207 patent/WO2021178991A1/en not_active Ceased
- 2021-03-01 AR ARP210100530A patent/AR121483A1/es unknown
- 2021-03-01 BR BR112022017398A patent/BR112022017398A2/pt unknown
- 2021-03-01 CA CA3172338A patent/CA3172338A1/en active Pending
- 2021-03-01 US US17/249,375 patent/US11702415B2/en active Active
- 2021-03-01 JP JP2022552324A patent/JP7681613B2/ja active Active
- 2021-03-01 MX MX2022010795A patent/MX2022010795A/es unknown
- 2021-03-01 CN CN202180017759.9A patent/CN115190878B/zh active Active
- 2021-03-01 IL IL295613A patent/IL295613A/en unknown
-
2022
- 2022-08-29 ZA ZA2022/09617A patent/ZA202209617B/en unknown
- 2022-08-31 CO CONC2022/0012476A patent/CO2022012476A2/es unknown
- 2022-08-31 CL CL2022002368A patent/CL2022002368A1/es unknown
-
2023
- 2023-05-31 US US18/326,732 patent/US12122773B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020518581A5 (enExample) | ||
| JP2020518582A5 (enExample) | ||
| JP2021535177A5 (enExample) | ||
| HRP20220330T1 (hr) | Kondenzirani imidazopiperidinski spoj, kao inhibitor jak | |
| CN116829571A (zh) | 新型螺旋吡咯烷衍生的抗病毒药物 | |
| JP2005531609A5 (enExample) | ||
| JP2018531982A5 (enExample) | ||
| US9981947B2 (en) | Polymorphic forms of nilotinib hydrochloride | |
| JP5344942B2 (ja) | 多形性形態 | |
| TW200528097A (en) | Novel thiazolidin-4-one derivatives | |
| JP2022532404A5 (enExample) | ||
| US20170057916A1 (en) | Novel forms of apremilast and the process of making the same | |
| JP2023103328A (ja) | ビランテロールトリフェニル酢酸塩の新規な結晶形態及びこれらの調製プロセス | |
| KR20120098816A (ko) | 메틸｛４，６?디아미노?２?〔１?（２?플루오로벤질）?１ｈ?피라졸로〔３，４?ｂ〕피리딘?３?일〕피리미딘?５?일｝카르바메이트의 신규한 다형체 형상 | |
| CA3133803A1 (en) | Solid forms of (e)-3-[2-(2-thienyl)vinyl]-1h-pyrazole | |
| JP2018521001A (ja) | 化合物 （ｓ）−３−｛４−［５−（２−シクロペンチル−６−メトキシ−ピリジン−４−イル）−［１，２，４］オキサジアゾール−３−イル］−２−エチル−６−メチル−フェノキシ｝−プロパン−１，２−ジオールの結晶形 | |
| JP2018522945A5 (enExample) | ||
| TW202411221A (zh) | 一種三嗪二酮類衍生物的晶型及製備方法 | |
| JP2019509286A5 (enExample) | ||
| RU2018135072A (ru) | Кристаллическая (2s,4r)-5-(5'-хлор-2'-фтор-[1,1'-бифенил]-4-ил)-2-(этоксиметил)-4-(3-гидроксиизоксазол-5-карбоксамидо)-2-метилпентановая кислота и ее применения | |
| WO2010111951A1 (zh) | 普拉格雷氢溴酸盐的晶体 | |
| KR20150054860A (ko) | 포스파티딜이노시톨 3-키나아제 억제제의 정제 제형 | |
| JP2025511126A5 (enExample) | ||
| JP2022526973A5 (enExample) | ||
| JP2005532364A5 (enExample) |