JP2023514128A5 - - Google Patents
Info
- Publication number
- JP2023514128A5 JP2023514128A5 JP2022547164A JP2022547164A JP2023514128A5 JP 2023514128 A5 JP2023514128 A5 JP 2023514128A5 JP 2022547164 A JP2022547164 A JP 2022547164A JP 2022547164 A JP2022547164 A JP 2022547164A JP 2023514128 A5 JP2023514128 A5 JP 2023514128A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- ligand
- seq
- acid sequence
- 7rαγc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062969432P | 2020-02-03 | 2020-02-03 | |
| US62/969,432 | 2020-02-03 | ||
| US202063041158P | 2020-06-19 | 2020-06-19 | |
| US63/041,158 | 2020-06-19 | ||
| PCT/US2021/016361 WO2021158623A1 (en) | 2020-02-03 | 2021-02-03 | IL-7Rαγc BINDING COMPOUNDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023514128A JP2023514128A (ja) | 2023-04-05 |
| JP2023514128A5 true JP2023514128A5 (enExample) | 2024-02-14 |
Family
ID=77200524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022547164A Pending JP2023514128A (ja) | 2020-02-03 | 2021-02-03 | ＩＬ－７Ｒαγｃ結合化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11746139B2 (enExample) |
| EP (1) | EP4100427A4 (enExample) |
| JP (1) | JP2023514128A (enExample) |
| KR (1) | KR20220139918A (enExample) |
| CN (1) | CN115315435A (enExample) |
| AU (2) | AU2021217353A1 (enExample) |
| BR (1) | BR112022015002A2 (enExample) |
| CA (1) | CA3166816A1 (enExample) |
| IL (1) | IL295304A (enExample) |
| MX (1) | MX2022009390A (enExample) |
| TW (2) | TW202342505A (enExample) |
| WO (1) | WO2021158623A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021002250A2 (pt) | 2018-08-06 | 2021-07-20 | Medikine, Inc. | compostos de ligação ao receptor de il-2 |
| JP7427286B2 (ja) | 2019-11-05 | 2024-02-05 | メディカイン、インコーポレイテッド | ＩＬ－２ＲβγＣ結合化合物 |
| IL292803A (en) | 2019-11-05 | 2022-07-01 | Medikine Inc | Dual il-2 receptor and il-7 receptor binding compounds, compositions comprising same and uses thereof |
| CA3166816A1 (en) | 2020-02-03 | 2021-08-12 | William J. Dower | Il-7r.alpha..gamma.c binding compounds |
| MX2022009302A (es) * | 2020-02-03 | 2022-11-16 | Medikine Inc | Compuestos de unión a il-7r¿. |
| CA3197344A1 (en) * | 2020-11-04 | 2022-05-12 | William J. Dower | Il-2r.beta.yc binding compounds and uses thereof |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| US11999771B2 (en) * | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
| WO2024054874A1 (en) | 2022-09-06 | 2024-03-14 | Medikine, Inc. | Use of il-2r-beta-gamma agonist peptides in cell manufacturing |
| WO2024054870A1 (en) | 2022-09-06 | 2024-03-14 | Medikine, Inc. | Use of il-7r-alpha-gamma agonist peptides in cell manufacturing |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635597A (en) | 1994-05-27 | 1997-06-03 | Affymax Technologies, N.V. | Peptides that bind IL-2 receptors |
| DK1454138T3 (da) | 2001-12-04 | 2012-02-13 | Merck Patent Gmbh | Immunocytokiner med moduleret selektivitet |
| US20050054054A1 (en) * | 2002-11-12 | 2005-03-10 | Foss Francine M. | Interleukin-7 molecules with altered biological properties |
| ES2305886T3 (es) | 2003-12-30 | 2008-11-01 | Merck Patent Gmbh | Proteinas de fusion de il-7 con porciones de anticuerpo, su preparacion y su empleo. |
| RU2437893C2 (ru) | 2004-12-09 | 2011-12-27 | Мерк Патент Гмбх | Варианты il-7 со сниженной иммуногенностью |
| JP2008525033A (ja) | 2004-12-22 | 2008-07-17 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | Ｂ群連鎖球菌 |
| US20120210458A9 (en) | 2009-02-27 | 2012-08-16 | Yongwei Cao | Isolated Novel Nucleic Acid and Protein Molecules from Corn and Methods of Using Thereof |
| WO2012065086A1 (en) | 2010-11-12 | 2012-05-18 | Nektar Therapeutics | Conjugates of an il-2 moiety and a polymer |
| CA2820956C (en) * | 2010-12-10 | 2016-05-03 | University Of Central Florida Research Foundation, Inc. | Methods and compositions comprising il-7 receptor ligands |
| EP2665486B1 (en) | 2011-01-18 | 2019-12-25 | Bioniz, LLC | Compositions for modulating gamma-c-cytokine activity |
| WO2015164815A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| PT3172227T (pt) | 2014-07-21 | 2019-12-06 | Delinia Inc | Moléculas que ativam seletivamente células t reguladoras para o tratamento de doenças autoimuneis |
| AU2015301936B2 (en) | 2014-08-11 | 2019-03-07 | Delinia, Inc. | Modified IL-2 variants that selectively activate regulatory T cells for the treatment of autoimmune diseases |
| PT3328894T (pt) * | 2015-08-06 | 2019-02-13 | Agency Science Tech & Res | Anticorpos de cadeia comum gama/il2rbeta |
| AU2016341529B2 (en) | 2015-10-22 | 2023-03-30 | Juno Therapeutics Gmbh | Methods for culturing cells and kits and apparatus for same |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| AU2017213659B2 (en) | 2016-02-05 | 2024-04-18 | Washington University | Compositions and methods for targeted cytokine delivery |
| EP3538548A4 (en) | 2016-11-08 | 2020-08-19 | Delinia, Inc. | IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES |
| JP6986559B2 (ja) | 2016-12-09 | 2022-01-05 | オセ イムノセラピューティクス | Ｃｄ１２７に対して方向付けられた抗体及びポリペプチド |
| AU2017378308A1 (en) | 2016-12-13 | 2019-06-20 | Delinia, Inc. | Multivalent regulatory T cell modulators |
| BR112021002250A2 (pt) | 2018-08-06 | 2021-07-20 | Medikine, Inc. | compostos de ligação ao receptor de il-2 |
| US11248025B2 (en) | 2019-06-03 | 2022-02-15 | Medikine, Inc. | IL-2alpha receptor subunit binding compounds |
| JP7427286B2 (ja) | 2019-11-05 | 2024-02-05 | メディカイン、インコーポレイテッド | ＩＬ－２ＲβγＣ結合化合物 |
| US20220119492A1 (en) | 2019-11-05 | 2022-04-21 | Medikine, Inc. | Il-2r-beta-gamma binding compounds and uses thereof |
| IL292803A (en) | 2019-11-05 | 2022-07-01 | Medikine Inc | Dual il-2 receptor and il-7 receptor binding compounds, compositions comprising same and uses thereof |
| WO2021122866A1 (en) | 2019-12-17 | 2021-06-24 | Ose Immunotherapeutics | Bifunctional molecules comprising an il-7 variant |
| CA3166816A1 (en) | 2020-02-03 | 2021-08-12 | William J. Dower | Il-7r.alpha..gamma.c binding compounds |
| MX2022009302A (es) | 2020-02-03 | 2022-11-16 | Medikine Inc | Compuestos de unión a il-7r¿. |
| CA3197344A1 (en) | 2020-11-04 | 2022-05-12 | William J. Dower | Il-2r.beta.yc binding compounds and uses thereof |
| US11999771B2 (en) | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
-
2021
- 2021-02-03 CA CA3166816A patent/CA3166816A1/en active Pending
- 2021-02-03 BR BR112022015002A patent/BR112022015002A2/pt not_active IP Right Cessation
- 2021-02-03 TW TW112126553A patent/TW202342505A/zh unknown
- 2021-02-03 IL IL295304A patent/IL295304A/en unknown
- 2021-02-03 CN CN202180022881.5A patent/CN115315435A/zh not_active Withdrawn
- 2021-02-03 EP EP21750982.7A patent/EP4100427A4/en not_active Withdrawn
- 2021-02-03 KR KR1020227030327A patent/KR20220139918A/ko not_active Withdrawn
- 2021-02-03 JP JP2022547164A patent/JP2023514128A/ja active Pending
- 2021-02-03 MX MX2022009390A patent/MX2022009390A/es unknown
- 2021-02-03 US US17/166,462 patent/US11746139B2/en active Active
- 2021-02-03 TW TW110104084A patent/TWI812918B/zh active
- 2021-02-03 AU AU2021217353A patent/AU2021217353A1/en not_active Abandoned
- 2021-02-03 WO PCT/US2021/016361 patent/WO2021158623A1/en not_active Ceased
-
2023
- 2023-07-11 US US18/350,543 patent/US11965015B2/en active Active
-
2024
- 2024-03-21 AU AU2024201860A patent/AU2024201860A1/en not_active Abandoned