JP2022553826A5 - - Google Patents
Info
- Publication number
- JP2022553826A5 JP2022553826A5 JP2022525813A JP2022525813A JP2022553826A5 JP 2022553826 A5 JP2022553826 A5 JP 2022553826A5 JP 2022525813 A JP2022525813 A JP 2022525813A JP 2022525813 A JP2022525813 A JP 2022525813A JP 2022553826 A5 JP2022553826 A5 JP 2022553826A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- amino acid
- acid sequence
- seq
- binding compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005177A JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962930758P | 2019-11-05 | 2019-11-05 | |
| US62/930,758 | 2019-11-05 | ||
| US202062969432P | 2020-02-03 | 2020-02-03 | |
| US62/969,432 | 2020-02-03 | ||
| US202063041158P | 2020-06-19 | 2020-06-19 | |
| US63/041,158 | 2020-06-19 | ||
| US202063071946P | 2020-08-28 | 2020-08-28 | |
| US63/071,946 | 2020-08-28 | ||
| PCT/US2020/058969 WO2021092081A1 (en) | 2019-11-05 | 2020-11-04 | Dual il-2r and il-7r binding compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005177A Division JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022553826A JP2022553826A (ja) | 2022-12-26 |
| JP2022553826A5 true JP2022553826A5 (enExample) | 2023-04-19 |
| JP7427287B2 JP7427287B2 (ja) | 2024-02-05 |
Family
ID=75686972
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022525813A Active JP7427287B2 (ja) | 2019-11-05 | 2020-11-04 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
| JP2024005177A Withdrawn JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005177A Withdrawn JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11248030B2 (enExample) |
| EP (1) | EP4055036A4 (enExample) |
| JP (2) | JP7427287B2 (enExample) |
| KR (1) | KR20220110209A (enExample) |
| AU (2) | AU2020378282B2 (enExample) |
| BR (1) | BR112022008750A2 (enExample) |
| CA (1) | CA3160466A1 (enExample) |
| IL (1) | IL292803A (enExample) |
| MX (1) | MX2022005404A (enExample) |
| TW (1) | TW202132330A (enExample) |
| WO (1) | WO2021092081A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210055694A (ko) * | 2018-08-06 | 2021-05-17 | 메디카인 인코포레이티드 | Il-2 수용체 결합 화합물 |
| AU2021201047B2 (en) * | 2018-08-06 | 2022-02-17 | Medikine, Inc. | Il-2 receptor binding compounds |
| CA3160466A1 (en) * | 2019-11-05 | 2021-05-14 | Medikine, Inc. | Dual il-2r and il-7r binding compounds |
| MX2022005411A (es) | 2019-11-05 | 2022-08-10 | Medikine Inc | COMPUESTOS DE UNIÓN A IL-2RßYC. |
| US11746139B2 (en) | 2020-02-03 | 2023-09-05 | Medikine, Inc. | IL-7Rαγc binding compounds |
| EP4240394A4 (en) * | 2020-11-04 | 2024-10-23 | Medikine, Inc. | IL-2R BETA-GAMMA C-BINDING COMPOUNDS AND USES THEREOF |
| US20250082777A1 (en) | 2022-01-10 | 2025-03-13 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| US11999771B2 (en) | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
| US20240101959A1 (en) * | 2022-09-06 | 2024-03-28 | Medikine, Inc. | Use of il-2r-beta-gamma agonist peptides in cell manufacturing |
| US20240100159A1 (en) * | 2022-09-06 | 2024-03-28 | Medikine, Inc. | Use of il-7r-alpha-gamma agonist peptides in cell manufacturing |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635597A (en) * | 1994-05-27 | 1997-06-03 | Affymax Technologies, N.V. | Peptides that bind IL-2 receptors |
| EP1454138B1 (en) * | 2001-12-04 | 2012-01-18 | Merck Patent GmbH | Immunocytokines with modulated selectivity |
| ES2356154T3 (es) * | 2003-07-21 | 2011-04-05 | Transgene S.A. | Citoquinas multifuncionales. |
| KR101163424B1 (ko) * | 2003-12-30 | 2012-07-13 | 메르크 파텐트 게엠베하 | Ｉｌ－７ 융합 단백질 |
| US20120210458A9 (en) * | 2009-02-27 | 2012-08-16 | Yongwei Cao | Isolated Novel Nucleic Acid and Protein Molecules from Corn and Methods of Using Thereof |
| ES2866674T3 (es) | 2010-11-12 | 2021-10-19 | Nektar Therapeutics | Conjugados de una fracción de IL-2 y un polímero |
| EP2649094B1 (en) | 2010-12-10 | 2016-04-27 | University of Central Florida Research Foundation, Inc. | Methods and compositions comprising il-7 receptor ligands |
| CA2824515C (en) | 2011-01-18 | 2022-09-13 | Bioniz, Llc | Compositions and methods for modulating gamma-c-cytokine activity |
| CN102775496B (zh) * | 2011-05-13 | 2014-10-08 | 中国医学科学院基础医学研究所 | 靶向清除hiv/siv的复合药物 |
| JP6592505B2 (ja) | 2014-04-24 | 2019-10-16 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | インターロイキン−２のスーパーアンタゴニスト、パーシャルアゴニスト及びアンタゴニスト |
| KR102493543B1 (ko) | 2014-07-21 | 2023-01-30 | 데리니아, 인크. | 자가면역 질환의 치료를 위한 조절 t 세포를 선택적으로 활성화시키는 분자 |
| JP6640834B2 (ja) * | 2014-08-11 | 2020-02-05 | デリニア， インコーポレイテッド | 自己免疫疾患の処置のために調節性ｔ細胞を選択的に活性化させる改変ｉｌ−２変異体 |
| PT3328894T (pt) | 2015-08-06 | 2019-02-13 | Agency Science Tech & Res | Anticorpos de cadeia comum gama/il2rbeta |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| US11053293B2 (en) | 2016-02-05 | 2021-07-06 | Washington University | Compositions and methods for targeted cytokine delivery |
| US20190216898A1 (en) * | 2016-05-06 | 2019-07-18 | Wang Mulin | Interleukin Combination and Use Thereof |
| EP3538548A4 (en) | 2016-11-08 | 2020-08-19 | Delinia, Inc. | IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES |
| CN110177564A (zh) | 2016-12-13 | 2019-08-27 | 德里尼亚公司 | 多价的调节t细胞调节剂 |
| KR20210055694A (ko) | 2018-08-06 | 2021-05-17 | 메디카인 인코포레이티드 | Il-2 수용체 결합 화합물 |
| MX2022005411A (es) | 2019-11-05 | 2022-08-10 | Medikine Inc | COMPUESTOS DE UNIÓN A IL-2RßYC. |
| CA3160466A1 (en) * | 2019-11-05 | 2021-05-14 | Medikine, Inc. | Dual il-2r and il-7r binding compounds |
| AU2021217959A1 (en) | 2020-02-03 | 2022-08-18 | Medikine, Inc. | IL-7Rα binding compounds |
| US11746139B2 (en) | 2020-02-03 | 2023-09-05 | Medikine, Inc. | IL-7Rαγc binding compounds |
-
2020
- 2020-11-04 CA CA3160466A patent/CA3160466A1/en active Pending
- 2020-11-04 WO PCT/US2020/058969 patent/WO2021092081A1/en not_active Ceased
- 2020-11-04 IL IL292803A patent/IL292803A/en unknown
- 2020-11-04 US US17/089,533 patent/US11248030B2/en not_active Expired - Fee Related
- 2020-11-04 AU AU2020378282A patent/AU2020378282B2/en not_active Ceased
- 2020-11-04 EP EP20884174.2A patent/EP4055036A4/en not_active Withdrawn
- 2020-11-04 JP JP2022525813A patent/JP7427287B2/ja active Active
- 2020-11-04 KR KR1020227018973A patent/KR20220110209A/ko not_active Withdrawn
- 2020-11-04 MX MX2022005404A patent/MX2022005404A/es unknown
- 2020-11-04 BR BR112022008750A patent/BR112022008750A2/pt not_active IP Right Cessation
- 2020-11-05 TW TW109138624A patent/TW202132330A/zh unknown
-
2022
- 2022-01-04 US US17/568,411 patent/US20220119465A1/en not_active Abandoned
-
2023
- 2023-08-10 AU AU2023214299A patent/AU2023214299A1/en not_active Abandoned
-
2024
- 2024-01-17 JP JP2024005177A patent/JP2024056696A/ja not_active Withdrawn