JP2022553826A5 - - Google Patents
Info
- Publication number
- JP2022553826A5 JP2022553826A5 JP2022525813A JP2022525813A JP2022553826A5 JP 2022553826 A5 JP2022553826 A5 JP 2022553826A5 JP 2022525813 A JP2022525813 A JP 2022525813A JP 2022525813 A JP2022525813 A JP 2022525813A JP 2022553826 A5 JP2022553826 A5 JP 2022553826A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- amino acid
- acid sequence
- seq
- binding compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024005177A JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962930758P | 2019-11-05 | 2019-11-05 | |
| US62/930,758 | 2019-11-05 | ||
| US202062969432P | 2020-02-03 | 2020-02-03 | |
| US62/969,432 | 2020-02-03 | ||
| US202063041158P | 2020-06-19 | 2020-06-19 | |
| US63/041,158 | 2020-06-19 | ||
| US202063071946P | 2020-08-28 | 2020-08-28 | |
| US63/071,946 | 2020-08-28 | ||
| PCT/US2020/058969 WO2021092081A1 (en) | 2019-11-05 | 2020-11-04 | Dual il-2r and il-7r binding compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005177A Division JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022553826A JP2022553826A (ja) | 2022-12-26 |
| JP2022553826A5 true JP2022553826A5 (enExample) | 2023-04-19 |
| JP7427287B2 JP7427287B2 (ja) | 2024-02-05 |
Family
ID=75686972
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022525813A Active JP7427287B2 (ja) | 2019-11-05 | 2020-11-04 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
| JP2024005177A Withdrawn JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024005177A Withdrawn JP2024056696A (ja) | 2019-11-05 | 2024-01-17 | 二重ｉｌ－２ｒおよびｉｌ－７ｒ結合化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11248030B2 (enExample) |
| EP (1) | EP4055036A4 (enExample) |
| JP (2) | JP7427287B2 (enExample) |
| KR (1) | KR20220110209A (enExample) |
| AU (2) | AU2020378282B2 (enExample) |
| BR (1) | BR112022008750A2 (enExample) |
| CA (1) | CA3160466A1 (enExample) |
| IL (1) | IL292803A (enExample) |
| MX (1) | MX2022005404A (enExample) |
| TW (1) | TW202132330A (enExample) |
| WO (1) | WO2021092081A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021201047B2 (en) * | 2018-08-06 | 2022-02-17 | Medikine, Inc. | Il-2 receptor binding compounds |
| BR112021002250A2 (pt) * | 2018-08-06 | 2021-07-20 | Medikine, Inc. | compostos de ligação ao receptor de il-2 |
| JP7427286B2 (ja) * | 2019-11-05 | 2024-02-05 | メディカイン、インコーポレイテッド | ＩＬ－２ＲβγＣ結合化合物 |
| IL292803A (en) * | 2019-11-05 | 2022-07-01 | Medikine Inc | Dual il-2 receptor and il-7 receptor binding compounds, compositions comprising same and uses thereof |
| CA3166816A1 (en) * | 2020-02-03 | 2021-08-12 | William J. Dower | Il-7r.alpha..gamma.c binding compounds |
| CA3197344A1 (en) * | 2020-11-04 | 2022-05-12 | William J. Dower | Il-2r.beta.yc binding compounds and uses thereof |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2023193015A1 (en) | 2022-04-01 | 2023-10-05 | Sana Biotechnology, Inc. | Cytokine receptor agonist and viral vector combination therapies |
| US11999771B2 (en) * | 2022-04-07 | 2024-06-04 | Medikine, Inc. | IL-7Rαγc ligand immunoglobulin fusion proteins |
| WO2024054874A1 (en) * | 2022-09-06 | 2024-03-14 | Medikine, Inc. | Use of il-2r-beta-gamma agonist peptides in cell manufacturing |
| WO2024054870A1 (en) * | 2022-09-06 | 2024-03-14 | Medikine, Inc. | Use of il-7r-alpha-gamma agonist peptides in cell manufacturing |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635597A (en) * | 1994-05-27 | 1997-06-03 | Affymax Technologies, N.V. | Peptides that bind IL-2 receptors |
| DK1454138T3 (da) * | 2001-12-04 | 2012-02-13 | Merck Patent Gmbh | Immunocytokiner med moduleret selektivitet |
| ATE500267T1 (de) * | 2003-07-21 | 2011-03-15 | Transgene Sa | Multifunktionelle cytokine |
| ES2305886T3 (es) | 2003-12-30 | 2008-11-01 | Merck Patent Gmbh | Proteinas de fusion de il-7 con porciones de anticuerpo, su preparacion y su empleo. |
| US20120210458A9 (en) * | 2009-02-27 | 2012-08-16 | Yongwei Cao | Isolated Novel Nucleic Acid and Protein Molecules from Corn and Methods of Using Thereof |
| WO2012065086A1 (en) | 2010-11-12 | 2012-05-18 | Nektar Therapeutics | Conjugates of an il-2 moiety and a polymer |
| CA2820956C (en) | 2010-12-10 | 2016-05-03 | University Of Central Florida Research Foundation, Inc. | Methods and compositions comprising il-7 receptor ligands |
| EP2665486B1 (en) | 2011-01-18 | 2019-12-25 | Bioniz, LLC | Compositions for modulating gamma-c-cytokine activity |
| CN102775496B (zh) * | 2011-05-13 | 2014-10-08 | 中国医学科学院基础医学研究所 | 靶向清除hiv/siv的复合药物 |
| WO2015164815A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| PT3172227T (pt) | 2014-07-21 | 2019-12-06 | Delinia Inc | Moléculas que ativam seletivamente células t reguladoras para o tratamento de doenças autoimuneis |
| AU2015301936B2 (en) * | 2014-08-11 | 2019-03-07 | Delinia, Inc. | Modified IL-2 variants that selectively activate regulatory T cells for the treatment of autoimmune diseases |
| PT3328894T (pt) | 2015-08-06 | 2019-02-13 | Agency Science Tech & Res | Anticorpos de cadeia comum gama/il2rbeta |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| AU2017213659B2 (en) | 2016-02-05 | 2024-04-18 | Washington University | Compositions and methods for targeted cytokine delivery |
| CN109562143A (zh) * | 2016-05-06 | 2019-04-02 | 王牧林 | 白细胞介素组合及其用途 |
| EP3538548A4 (en) | 2016-11-08 | 2020-08-19 | Delinia, Inc. | IL-2 VARIANTS FOR THE TREATMENT OF AUTOIMMUNE DISEASES |
| AU2017378308A1 (en) | 2016-12-13 | 2019-06-20 | Delinia, Inc. | Multivalent regulatory T cell modulators |
| BR112021002250A2 (pt) | 2018-08-06 | 2021-07-20 | Medikine, Inc. | compostos de ligação ao receptor de il-2 |
| JP7427286B2 (ja) | 2019-11-05 | 2024-02-05 | メディカイン、インコーポレイテッド | ＩＬ－２ＲβγＣ結合化合物 |
| IL292803A (en) * | 2019-11-05 | 2022-07-01 | Medikine Inc | Dual il-2 receptor and il-7 receptor binding compounds, compositions comprising same and uses thereof |
| MX2022009302A (es) | 2020-02-03 | 2022-11-16 | Medikine Inc | Compuestos de unión a il-7r¿. |
| CA3166816A1 (en) | 2020-02-03 | 2021-08-12 | William J. Dower | Il-7r.alpha..gamma.c binding compounds |
-
2020
- 2020-11-04 IL IL292803A patent/IL292803A/en unknown
- 2020-11-04 AU AU2020378282A patent/AU2020378282B2/en active Active
- 2020-11-04 EP EP20884174.2A patent/EP4055036A4/en not_active Withdrawn
- 2020-11-04 MX MX2022005404A patent/MX2022005404A/es unknown
- 2020-11-04 US US17/089,533 patent/US11248030B2/en not_active Expired - Fee Related
- 2020-11-04 CA CA3160466A patent/CA3160466A1/en active Pending
- 2020-11-04 BR BR112022008750A patent/BR112022008750A2/pt not_active IP Right Cessation
- 2020-11-04 WO PCT/US2020/058969 patent/WO2021092081A1/en not_active Ceased
- 2020-11-04 KR KR1020227018973A patent/KR20220110209A/ko not_active Withdrawn
- 2020-11-04 JP JP2022525813A patent/JP7427287B2/ja active Active
- 2020-11-05 TW TW109138624A patent/TW202132330A/zh unknown
-
2022
- 2022-01-04 US US17/568,411 patent/US20220119465A1/en not_active Abandoned
-
2023
- 2023-08-10 AU AU2023214299A patent/AU2023214299A1/en not_active Abandoned
-
2024
- 2024-01-17 JP JP2024005177A patent/JP2024056696A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022553826A5 (enExample) | ||
| JP5761831B2 (ja) | 癌及び慢性感染の治療のための作動薬活性を有するｉｌ−２由来のポリペプチド | |
| AU2020380296A1 (en) | IL-2RβγC binding compounds | |
| RU2363707C2 (ru) | Искусственные белки с пониженной иммуногенностью | |
| TWI886164B (zh) | 1價ccap生成物之製造方法 | |
| JP2021502810A5 (enExample) | ||
| JP2023506757A5 (enExample) | ||
| JP2011521662A5 (enExample) | ||
| JP2003507012A5 (enExample) | ||
| JP2022535924A5 (enExample) | ||
| CA2347411A1 (en) | Virus-like particles for the induction of autoantibodies | |
| JP2003505431A5 (enExample) | ||
| CN1972710B (zh) | 包含噬菌体纳米颗粒的方法和组合物 | |
| WO2023070317A1 (zh) | 基于dc细胞的双功能纳米抗体及其构建方法和应用 | |
| JP2008521426A5 (enExample) | ||
| JP2022542198A (ja) | アプタマーベース多重特異性治療剤 | |
| JP2023506763A5 (enExample) | ||
| CN111615518B (zh) | 阻断emt途径并克服癌干细胞的il8 | |
| AU707083B2 (en) | Inducing antibody response against self-proteins with the aid of foreign T-cell epitopes | |
| JP2009500298A5 (enExample) | ||
| JP2015512247A5 (enExample) | ||
| JP2023086734A5 (enExample) | ||
| CN104755619A (zh) | 用于预防猪水肿病的疫苗 | |
| CN112662695B (zh) | 一种细菌生物膜囊泡bbv作为疫苗载体的构建方法和应用 | |
| JP2006523185A5 (enExample) |