JP2023164918A5 - - Google Patents
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- Publication number
- JP2023164918A5 JP2023164918A5 JP2023142246A JP2023142246A JP2023164918A5 JP 2023164918 A5 JP2023164918 A5 JP 2023164918A5 JP 2023142246 A JP2023142246 A JP 2023142246A JP 2023142246 A JP2023142246 A JP 2023142246A JP 2023164918 A5 JP2023164918 A5 JP 2023164918A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- aryl
- optionally substituted
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025235397A JP2026031721A (ja) | 2017-09-26 | 2025-12-05 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762563375P | 2017-09-26 | 2017-09-26 | |
| US62/563,375 | 2017-09-26 | ||
| PCT/US2018/052797 WO2019067503A1 (en) | 2017-09-26 | 2018-09-26 | NEW USP7 INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA |
| JP2020515000A JP7402792B2 (ja) | 2017-09-26 | 2018-09-26 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515000A Division JP7402792B2 (ja) | 2017-09-26 | 2018-09-26 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025235397A Division JP2026031721A (ja) | 2017-09-26 | 2025-12-05 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023164918A JP2023164918A (ja) | 2023-11-14 |
| JP2023164918A5 true JP2023164918A5 (https=) | 2024-11-14 |
Family
ID=65903565
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515000A Active JP7402792B2 (ja) | 2017-09-26 | 2018-09-26 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
| JP2023142246A Pending JP2023164918A (ja) | 2017-09-26 | 2023-09-01 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
| JP2025235397A Pending JP2026031721A (ja) | 2017-09-26 | 2025-12-05 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515000A Active JP7402792B2 (ja) | 2017-09-26 | 2018-09-26 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025235397A Pending JP2026031721A (ja) | 2017-09-26 | 2025-12-05 | 多発性骨髄腫を治療するための新規なｕｓｐ７阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11465983B2 (https=) |
| EP (1) | EP3687537A4 (https=) |
| JP (3) | JP7402792B2 (https=) |
| AU (1) | AU2018342089B2 (https=) |
| CA (1) | CA3072353A1 (https=) |
| WO (1) | WO2019067503A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3072353A1 (en) | 2017-09-26 | 2019-04-04 | Dana-Farber Cancer Institute, Inc. | Usp7 inhibitors for treating multiple myeloma |
| JP7508449B2 (ja) * | 2018-10-22 | 2024-07-01 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｕｓｐ７の阻害 |
| MX2021006542A (es) * | 2018-12-06 | 2021-07-07 | Almac Discovery Ltd | Inhibidores de la usp19 para usarse en terapia. |
| EP3965749A4 (en) * | 2019-05-06 | 2023-06-21 | Valo Health, Inc. | ESCAPEMENT OF USP19 |
| EP4110393A1 (en) | 2020-02-28 | 2023-01-04 | Immunologik GmbH | Inhibitors of human deubiquitinases for the treatment of coronaviral infections |
| CN112047933B (zh) * | 2020-10-15 | 2022-06-14 | 郑州大学 | 喹唑啉酮类usp7抑制剂及其制备方法和应用 |
| GB202104097D0 (en) * | 2021-03-24 | 2021-05-05 | Almac Discovery Ltd | Pharmaceutical compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999053924A1 (en) * | 1998-04-17 | 1999-10-28 | Kyowa Hakko Kogyo Co., Ltd. | Analgetic agent |
| DE60326436D1 (en) | 2002-03-13 | 2009-04-16 | Janssen Pharmaceutica Nv | Aminoderivate als histone-deacetylase-inhibitoren |
| CA2656825C (en) | 2006-06-22 | 2013-12-10 | Prana Biotechnology Limited | Method of treatment and agents useful for same |
| EP2565186A1 (en) * | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Selective and reversible inhibitors of ubiquitin specific protease 7 |
| EP3253765A1 (en) * | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Thienopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| HK1248220A1 (zh) | 2015-02-05 | 2018-10-12 | Forma Therapeutics, Inc. | 喹唑啉酮和偶氮喹唑啉作为泛特丁胺蛋白酶7抑制剂 |
| US9938300B2 (en) * | 2015-02-05 | 2018-04-10 | Forma Therapeutics, Inc. | Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| GB201612938D0 (en) | 2016-07-26 | 2016-09-07 | Almac Discovery Ltd | Pharmaceutical compounds |
| GB201617758D0 (en) | 2016-10-20 | 2016-12-07 | Almac Discovery Limited | Pharmaceutical compounds |
| CA3072353A1 (en) | 2017-09-26 | 2019-04-04 | Dana-Farber Cancer Institute, Inc. | Usp7 inhibitors for treating multiple myeloma |
| JP7508449B2 (ja) | 2018-10-22 | 2024-07-01 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｕｓｐ７の阻害 |
-
2018
- 2018-09-26 CA CA3072353A patent/CA3072353A1/en active Pending
- 2018-09-26 WO PCT/US2018/052797 patent/WO2019067503A1/en not_active Ceased
- 2018-09-26 JP JP2020515000A patent/JP7402792B2/ja active Active
- 2018-09-26 AU AU2018342089A patent/AU2018342089B2/en active Active
- 2018-09-26 US US16/650,727 patent/US11465983B2/en active Active
- 2018-09-26 EP EP18862773.1A patent/EP3687537A4/en active Pending
-
2022
- 2022-09-02 US US17/902,512 patent/US20230265070A1/en active Pending
-
2023
- 2023-09-01 JP JP2023142246A patent/JP2023164918A/ja active Pending
-
2025
- 2025-12-05 JP JP2025235397A patent/JP2026031721A/ja active Pending
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