|
EP2510946B1
(en)
|
2007-02-07 |
2015-08-05 |
The Regents of The University of California |
Conjugates of synthetic tlr agonists and uses therefor
|
|
WO2009030996A1
(en)
|
2007-09-05 |
2009-03-12 |
Coley Pharmaceutical Group, Inc. |
Triazole compounds as toll-like receptor (tlr) agonists
|
|
EP2200639B1
(en)
|
2007-09-24 |
2016-03-30 |
Government of the USA, as Represented by the Secretary, Department of Health and Human Services |
Immunostimulatory combinations of tlr3 ligands with tlr2 and tlr9 agonists and methods of use
|
|
US9370558B2
(en)
|
2008-02-13 |
2016-06-21 |
President And Fellows Of Harvard College |
Controlled delivery of TLR agonists in structural polymeric devices
|
|
CA2732437C
(en)
|
2008-08-01 |
2017-11-21 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
EP2486134B1
(en)
|
2009-10-06 |
2014-01-08 |
Panacela Labs, Inc. |
Use of toll-like receptor and agonist for treating cancer
|
|
WO2011041897A1
(en)
*
|
2009-10-06 |
2011-04-14 |
Angiochem Inc. |
Compositions and methods for the transport of therapeutic agents
|
|
KR101866893B1
(ko)
|
2010-10-01 |
2018-06-14 |
벤티알엑스 파마슈티칼스 인코포레이티드 |
Tlr 아고니스트의 치료적 용도 및 병용 요법
|
|
EP2858722B8
(en)
|
2012-06-08 |
2018-02-21 |
Aduro BioTech, Inc. |
Compostions and methods for cancer immunotherapy
|
|
SG11201502796RA
(en)
|
2012-12-13 |
2015-05-28 |
Aduro Biotech Inc |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
|
JP2016524593A
(ja)
|
2013-04-29 |
2016-08-18 |
メモリアル スローン−ケタリング キャンサー センター |
セカンドメッセンジャーのシグナル伝達を変えるための組成物及び方法
|
|
CN105377867B
(zh)
|
2013-05-03 |
2019-11-12 |
加利福尼亚大学董事会 |
I型干扰素的环状二核苷酸诱导
|
|
EP2996472B1
(en)
|
2013-05-18 |
2019-03-27 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting "stimulator of interferon gene" dependent signalling
|
|
CU24377B1
(es)
|
2013-05-18 |
2018-12-05 |
Aduro Biotech Inc |
Dinucléotidos de purina cíclicos y composiciones de los mismos útiles para inducir la producción de interferón de tipo i dependientes de sting
|
|
US10176292B2
(en)
|
2013-07-31 |
2019-01-08 |
Memorial Sloan-Kettering Cancer Center |
STING crystals and modulators
|
|
JP2016538344A
(ja)
|
2013-11-19 |
2016-12-08 |
ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago |
癌処置としてのstingアゴニストの使用
|
|
EP3152217B1
(en)
|
2014-06-04 |
2018-08-01 |
GlaxoSmithKline Intellectual Property Development Limited |
Cyclic di-nucleotides as modulators of sting
|
|
DK3233882T3
(da)
|
2014-12-16 |
2020-01-27 |
Kayla Therapeutics |
Fluorinerede cykliske dinukleotider til cytokininduktion
|
|
EP3233191A1
(en)
|
2014-12-16 |
2017-10-25 |
Invivogen |
Combined use of a chemotherapeutic agent and a cyclic dinucleotide for cancer treatment
|
|
GB201501462D0
(en)
|
2015-01-29 |
2015-03-18 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
TWI706958B
(zh)
|
2015-03-10 |
2020-10-11 |
美商艾杜諾生物科技公司 |
活化「干擾素基因刺激因子」依賴性訊息傳導之組合物及方法
|
|
CN108137641B
(zh)
|
2015-08-13 |
2022-04-01 |
默沙东公司 |
作为sting激动剂的环状双核苷酸化合物
|
|
KR20180066241A
(ko)
|
2015-10-28 |
2018-06-18 |
아두로 바이오테크, 인코포레이티드 |
“인터페론 유전자의 자극제”-의존성 신호전달을 활성화시키기 위한 조성물 및 방법
|
|
NZ742327A
(en)
*
|
2015-11-18 |
2020-01-31 |
Aruna Biomedical Inc |
Neural cell extracellular vessicles
|
|
IL280430B2
(en)
|
2016-03-18 |
2023-11-01 |
Univ Texas |
Cyclic dinucleotide compounds and methods of use
|
|
SG10201900628RA
(en)
|
2016-04-07 |
2019-02-27 |
Glaxosmithkline Ip Dev Ltd |
Heterocyclic amides useful as protein modulators
|
|
WO2017175156A1
(en)
|
2016-04-07 |
2017-10-12 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides useful as protein modulators
|
|
WO2018070939A1
(en)
*
|
2016-10-12 |
2018-04-19 |
Agency For Science, Technology And Research |
Method for lyophilising an exosome
|
|
US20180193270A1
(en)
*
|
2016-11-29 |
2018-07-12 |
PureTech Health LLC |
Exosomes for delivery of therapeutic agents
|
|
WO2018100558A2
(en)
|
2016-12-01 |
2018-06-07 |
Takeda Pharmaceutical Company Limited |
Cyclic dinucleotide
|
|
KR20240033086A
(ko)
|
2017-08-25 |
2024-03-12 |
코디악 바이오사이언시즈, 인크. |
막 단백질을 사용한 치료용 엑소좀의 제조
|
|
US20190151456A1
(en)
|
2017-11-17 |
2019-05-23 |
Codiak Biosciences, Inc. |
Compositions of Engineered Exosomes and Methods of Loading Luminal Exosome Payloads
|
|
US20190175506A1
(en)
*
|
2017-11-17 |
2019-06-13 |
Codiak Biosciences, Inc. |
Loading of Extracellular Vesicles through Imparting of Mechanical Shear
|
|
EP3731849A4
(en)
*
|
2017-12-28 |
2021-12-01 |
Codiak BioSciences, Inc. |
EXOSOME FOR IMMUNONCOLOGICAL AND ANTI-INFLAMMATORY THERAPY
|
|
GB201802163D0
(en)
*
|
2018-02-09 |
2018-03-28 |
Evox Therapeutics Ltd |
Compositions for EV storage and formulation
|
|
EP3752615B1
(en)
*
|
2018-02-12 |
2025-08-27 |
Lonza Sales AG |
Methods and compositions for macrophage polarization
|
|
TW202003032A
(zh)
*
|
2018-03-23 |
2020-01-16 |
美商科迪亞克生物科學公司 |
包含s t i n g 促效劑之胞外囊泡
|
|
EP4059510B1
(en)
|
2018-11-16 |
2025-05-21 |
Lonza Sales AG |
Engineered extracellular vesicles and uses thereof
|
|
EP3941607A1
(en)
*
|
2019-03-21 |
2022-01-26 |
Codiak BioSciences, Inc. |
Process for preparing extracellular vesicles
|