JP2022536728A5 - - Google Patents
Info
- Publication number
- JP2022536728A5 JP2022536728A5 JP2021573593A JP2021573593A JP2022536728A5 JP 2022536728 A5 JP2022536728 A5 JP 2022536728A5 JP 2021573593 A JP2021573593 A JP 2021573593A JP 2021573593 A JP2021573593 A JP 2021573593A JP 2022536728 A5 JP2022536728 A5 JP 2022536728A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- benzyl
- oxy
- butanoic acid
- fluorophenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860571P | 2019-06-12 | 2019-06-12 | |
| US62/860,571 | 2019-06-12 | ||
| PCT/US2020/037527 WO2020252336A1 (en) | 2019-06-12 | 2020-06-12 | Dibenzylamines as amino acid transport inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022536728A JP2022536728A (ja) | 2022-08-18 |
| JP2022536728A5 true JP2022536728A5 (enExample) | 2023-06-20 |
Family
ID=71409525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021573593A Pending JP2022536728A (ja) | 2019-06-12 | 2020-06-12 | アミノ酸輸送阻害剤としてのジベンジルアミン類 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220265590A1 (enExample) |
| EP (1) | EP3983377A1 (enExample) |
| JP (1) | JP2022536728A (enExample) |
| CN (1) | CN114269715A (enExample) |
| AU (1) | AU2020291936A1 (enExample) |
| CA (1) | CA3141414A1 (enExample) |
| WO (1) | WO2020252336A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019217307A1 (en) | 2018-05-07 | 2019-11-14 | Mirati Therapeutics, Inc. | Kras g12c inhibitors |
| ES3004338T3 (en) | 2018-09-10 | 2025-03-12 | Mirati Therapeutics Inc | Combination therapies |
| KR102871791B1 (ko) | 2018-09-10 | 2025-10-15 | 미라티 테라퓨틱스, 인크. | 병용 요법 |
| WO2020055761A1 (en) | 2018-09-10 | 2020-03-19 | Mirati Therapeutics, Inc. | Combination therapies |
| JP2022500385A (ja) | 2018-09-10 | 2022-01-04 | ミラティ セラピューティクス， インコーポレイテッド | 組み合わせ療法 |
| CA3112129A1 (en) | 2018-12-05 | 2020-06-11 | Mirati Therapeutics, Inc. | Combination therapies |
| JP7592601B2 (ja) | 2019-01-10 | 2024-12-02 | ミラティ セラピューティクス， インコーポレイテッド | Ｋｒａｓ ｇ１２ｃ阻害剤 |
| CA3148745A1 (en) | 2019-08-29 | 2021-03-04 | Xiaolun Wang | Kras g12d inhibitors |
| CN114761012B (zh) | 2019-09-24 | 2025-03-21 | 米拉蒂治疗股份有限公司 | 组合疗法 |
| KR20220130126A (ko) | 2019-12-20 | 2022-09-26 | 미라티 테라퓨틱스, 인크. | Sos1 억제제 |
| US12286431B2 (en) | 2020-09-11 | 2025-04-29 | Mirati Therapeutics, Inc. | Crystalline forms of a KRas G12C inhibitor |
| US12398154B2 (en) | 2020-12-15 | 2025-08-26 | Mirati Therapeutics, Inc. | Azaquinazoline pan-KRas inhibitors |
| EP4262803A4 (en) | 2020-12-16 | 2025-03-12 | Mirati Therapeutics, Inc. | Tetrahydropyridopyrimidine pan-kras inhibitors |
| US20240174658A1 (en) * | 2021-03-01 | 2024-05-30 | Vanderbilt University | Heteroaromatic Inhibitors of Cancer Metabolism |
| KR102635329B1 (ko) * | 2021-07-21 | 2024-02-13 | 경북대학교 산학협력단 | 혈관평활근세포의 증식 또는 이동 억제 효과를 갖는 화합물을 유효성분으로 포함하는 혈관평활근세포 이상 증식성 질환의 예방 또는 치료용 약학적 조성물 |
| CN117466761B (zh) * | 2022-07-21 | 2026-04-28 | 中国药科大学 | 谷氨酰胺转运抑制剂、药物组合物和应用 |
| CN116410152B (zh) * | 2023-04-13 | 2023-11-03 | 江苏征瑞医药科技有限公司 | 一种抑制asct2的小分子化合物、其衍生物及其应用 |
| CN117550997B (zh) * | 2023-11-09 | 2025-12-19 | 中国药科大学 | 一种lat1抑制剂及其制法和应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57501692A (enExample) | 1980-09-24 | 1982-09-16 | ||
| ATE53862T1 (de) | 1982-01-22 | 1990-06-15 | Cetus Corp | Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel. |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| US6605712B1 (en) | 1990-12-20 | 2003-08-12 | Arch Development Corporation | Gene transcription and ionizing radiation: methods and compositions |
| WO1998042752A1 (en) | 1997-03-21 | 1998-10-01 | Brigham And Women's Hospital Inc. | Immunotherapeutic ctla-4 binding peptides |
| PT1210428E (pt) | 1999-08-23 | 2015-07-21 | Genetics Inst Llc | Pd-1, um recetor para b7-4 e suas utilizações |
| CN102766210B (zh) | 1999-08-24 | 2015-07-08 | E.R.施贵宝&圣斯有限责任公司 | 人ctla-4抗体及其应用 |
| PT1537878E (pt) | 2002-07-03 | 2010-11-18 | Ono Pharmaceutical Co | Composições de imunopotenciação |
| PL2161336T5 (pl) | 2005-05-09 | 2017-10-31 | Ono Pharmaceutical Co | Ludzkie przeciwciała monoklonalne przeciwko białku Programmed Death 1 (PD-1) oraz sposoby leczenia raka z zastosowaniem samych przeciwciał anty-PD-1 lub w połączeniu z innymi środkami immunoterapeutycznymi |
| KR101586617B1 (ko) | 2007-06-18 | 2016-01-20 | 머크 샤프 앤 도메 비.브이. | 사람 프로그램된 사멸 수용체 ｐｄ-1에 대한 항체 |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| ES2545609T3 (es) | 2008-08-25 | 2015-09-14 | Amplimmune, Inc. | Composiciones de antagonistas de PD-1 y métodos de uso |
| EP4209510B1 (en) | 2008-12-09 | 2024-01-31 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| JP4965623B2 (ja) | 2009-09-30 | 2012-07-04 | インターナショナル・ビジネス・マシーンズ・コーポレーション | 所定のソフトウェアの実行パラメータを入力フィールドへ入力することを支援するための方法、システム、およびプログラム |
| US8907053B2 (en) | 2010-06-25 | 2014-12-09 | Aurigene Discovery Technologies Limited | Immunosuppression modulating compounds |
| WO2013006490A2 (en) | 2011-07-01 | 2013-01-10 | Cellerant Therapeutics, Inc. | Antibodies that specifically bind to tim3 |
| US20130071403A1 (en) | 2011-09-20 | 2013-03-21 | Vical Incorporated | Synergistic anti-tumor efficacy using alloantigen combination immunotherapy |
| US9624298B2 (en) | 2011-11-28 | 2017-04-18 | Merck Patent Gmbh | Anti-PD-L1 antibodies and uses thereof |
| AU2013263076B2 (en) | 2012-05-15 | 2017-08-31 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting PD-1/PD-L1 signaling |
| UY34887A (es) | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| CA2916638C (en) | 2012-07-31 | 2021-01-12 | The Brigham And Women's Hospital, Inc. | Modulation of the immune response |
| US10280221B2 (en) | 2013-03-15 | 2019-05-07 | Glaxosmithkline Intellectual Property Development Limited | Anti-LAG-3 binding proteins |
| CN105873606B (zh) | 2013-09-11 | 2020-12-29 | 米迪缪尼有限公司 | 用于治疗肿瘤的抗b7-h1抗体 |
| US20150252434A1 (en) | 2014-03-07 | 2015-09-10 | University Health Network | Methods and compositions for detection of targets involved in cancer metastasis |
| WO2015138920A1 (en) | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
| WO2018107173A1 (en) * | 2016-12-09 | 2018-06-14 | Vanderbilt University | Glutamine transport inhibitors and methods for treating cancer |
-
2020
- 2020-06-12 US US17/618,838 patent/US20220265590A1/en active Pending
- 2020-06-12 JP JP2021573593A patent/JP2022536728A/ja active Pending
- 2020-06-12 EP EP20735757.5A patent/EP3983377A1/en not_active Withdrawn
- 2020-06-12 WO PCT/US2020/037527 patent/WO2020252336A1/en not_active Ceased
- 2020-06-12 CA CA3141414A patent/CA3141414A1/en active Pending
- 2020-06-12 CN CN202080056932.1A patent/CN114269715A/zh active Pending
- 2020-06-12 AU AU2020291936A patent/AU2020291936A1/en not_active Abandoned
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