JP2022529775A5 - - Google Patents
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- Publication number
- JP2022529775A5 JP2022529775A5 JP2021561683A JP2021561683A JP2022529775A5 JP 2022529775 A5 JP2022529775 A5 JP 2022529775A5 JP 2021561683 A JP2021561683 A JP 2021561683A JP 2021561683 A JP2021561683 A JP 2021561683A JP 2022529775 A5 JP2022529775 A5 JP 2022529775A5
- Authority
- JP
- Japan
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962839548P | 2019-04-26 | 2019-04-26 | |
| US62/839,548 | 2019-04-26 | ||
| US201962923924P | 2019-10-21 | 2019-10-21 | |
| US62/923,924 | 2019-10-21 | ||
| PCT/US2020/029895 WO2020219933A1 (en) | 2019-04-26 | 2020-04-24 | Variant aav capsids for intravitreal delivery |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022529775A JP2022529775A (ja) | 2022-06-24 |
| JP2022529775A5 true JP2022529775A5 (https=) | 2023-05-11 |
| JPWO2020219933A5 JPWO2020219933A5 (https=) | 2023-05-11 |
| JP7623703B2 JP7623703B2 (ja) | 2025-01-29 |
Family
ID=70740759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021561683A Active JP7623703B2 (ja) | 2019-04-26 | 2020-04-24 | 硝子体内送達のためのバリアントａａｖキャプシド |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11510950B2 (https=) |
| EP (1) | EP3958911A1 (https=) |
| JP (1) | JP7623703B2 (https=) |
| KR (1) | KR20220004114A (https=) |
| CN (2) | CN113766934B (https=) |
| AU (1) | AU2020262948A1 (https=) |
| BR (1) | BR112021020957A2 (https=) |
| CA (1) | CA3130217A1 (https=) |
| IL (1) | IL287438A (https=) |
| MX (2) | MX2021012311A (https=) |
| SG (1) | SG11202108928XA (https=) |
| TW (2) | TW202532428A (https=) |
| WO (1) | WO2020219933A1 (https=) |
| ZA (1) | ZA202105975B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3841109A4 (en) * | 2018-08-21 | 2022-09-21 | Massachusetts Eye and Ear Infirmary | COMPOSITIONS AND METHODS TO MODULATE THE TRANSDUCTION EFFICIENCY OF ADENO-ASSOCIATED VIRUSES |
| EP3861010A1 (en) | 2018-10-02 | 2021-08-11 | Voyager Therapeutics, Inc. | Redirection of tropism of aav capsids |
| CN116096734A (zh) | 2020-05-13 | 2023-05-09 | 沃雅戈治疗公司 | Aav衣壳的向性的重定向 |
| CN115044614B (zh) * | 2021-03-09 | 2023-10-20 | 上海目镜生物医药科技有限公司 | 一种用于基因靶向与表达的aav-8型血清型的改造型载体及其构建方法及应用 |
| US12385064B2 (en) * | 2021-03-26 | 2025-08-12 | Adverum Biotechnologies, Inc. | Intravitreal dosing for delivery of polynucleotides to retinal cones |
| CN113648432B (zh) * | 2021-03-31 | 2024-01-19 | 中山大学中山眼科中心 | rAAV2/Retro作为针对视网膜感光细胞的递送系统及其在制备治疗视网膜疾病药物中的应用 |
| MX2024004936A (es) | 2021-11-02 | 2024-05-08 | Voyager Therapeutics Inc | Variantes de capsides de aav y sus usos. |
| AU2024242380A1 (en) * | 2023-03-31 | 2025-11-06 | Exegenesis Bio Singapore Pte. Ltd. | Variant aav9 capsid proteins and uses thereof |
| WO2024211831A1 (en) | 2023-04-05 | 2024-10-10 | Adverum Biotechnologies, Inc. | Immune landscape signatures for ocular inflammation |
| AU2024297654A1 (en) | 2023-07-13 | 2026-01-22 | Kriya Therapeutics, Inc. | Complement pathway inhibitor fusions and methods of using the same |
| CN117247434B (zh) * | 2023-11-10 | 2024-02-02 | 上海朗昇生物科技有限公司 | 衣壳修饰型病毒载体及其制备和用途 |
| CN118955654B (zh) * | 2024-10-15 | 2025-05-16 | 朗信启昇(苏州)生物制药有限公司 | 具有变异衣壳的腺相关病毒病毒体及其用途 |
| WO2026084101A1 (ko) | 2024-10-18 | 2026-04-23 | 주식회사 아바타테라퓨틱스 | 아데노연관바이러스 변이체 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| AU684498B2 (en) | 1993-03-25 | 1997-12-18 | Merck & Co., Inc. | Inhibitor of vascular endothelial cell growth factor |
| JP3957765B2 (ja) | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗ｖｅｇｆ抗体 |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| WO2004075861A2 (en) | 2003-02-26 | 2004-09-10 | Children's Hospital, Inc. | Recombinant adeno-associated virus production |
| US9441244B2 (en) | 2003-06-30 | 2016-09-13 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| EP1919497B1 (en) | 2005-07-22 | 2020-02-12 | The Board of Trustees of the Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| EP2019588A4 (en) | 2006-05-04 | 2010-11-24 | Univ Wayne State | RESTORATION OF VISUAL RESPONSES BY IN VIVO ADMINISTRATION OF NUCLEIC ACIDS OF RHODOPSIN |
| EP2287323A1 (en) * | 2009-07-31 | 2011-02-23 | Association Institut de Myologie | Widespread gene delivery to the retina using systemic administration of AAV vectors |
| JP6208580B2 (ja) | 2010-05-17 | 2017-10-04 | サンガモ セラピューティクス， インコーポレイテッド | 新規のｄｎａ結合タンパク質及びその使用 |
| HRP20171334T1 (hr) * | 2011-04-22 | 2017-11-17 | The Regents Of The University Of California | Virioni adeno-povezanog virusa s kapsid varijantom i postupci njihove upotrebe |
| TWI775096B (zh) | 2012-05-15 | 2022-08-21 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| TWI738632B (zh) | 2014-11-07 | 2021-09-11 | 瑞士商諾華公司 | 穩定的含有高濃度抗vegf抗體之蛋白質溶液調配物 |
| MY187898A (en) * | 2015-03-02 | 2021-10-27 | Adverum Biotechnologies Inc | Compositions and methods for intravitreal delivery of polynucleotides to retinal cones |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
| CA3022667A1 (en) | 2016-05-03 | 2017-11-09 | Adverum Biotechnologies, Inc. | Organotypic pig retina culture system |
| FI3445773T3 (fi) * | 2016-05-13 | 2023-03-30 | 4D Molecular Therapeutics Inc | Adenoassosioituneen viruksen kapsidimuunnoksia ja niiden käyttömenetelmiä |
| EP3827812B1 (en) * | 2016-07-29 | 2025-10-29 | The Regents of the University of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
| CA3040179A1 (en) | 2016-10-19 | 2018-04-26 | Adverum Biotechnologies, Inc. | Modified aav capsids and uses thereof |
| AU2018227483A1 (en) * | 2017-02-28 | 2019-09-12 | Adverum Biotechnologies, Inc. | Modified AAV capsids and uses thereof |
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2020
- 2020-04-23 TW TW113141337A patent/TW202532428A/zh unknown
- 2020-04-23 TW TW109113631A patent/TWI862583B/zh active
- 2020-04-24 CA CA3130217A patent/CA3130217A1/en active Pending
- 2020-04-24 CN CN202080031274.0A patent/CN113766934B/zh active Active
- 2020-04-24 AU AU2020262948A patent/AU2020262948A1/en active Pending
- 2020-04-24 WO PCT/US2020/029895 patent/WO2020219933A1/en not_active Ceased
- 2020-04-24 US US16/858,042 patent/US11510950B2/en active Active
- 2020-04-24 CN CN202411569264.9A patent/CN119708162A/zh active Pending
- 2020-04-24 SG SG11202108928XA patent/SG11202108928XA/en unknown
- 2020-04-24 JP JP2021561683A patent/JP7623703B2/ja active Active
- 2020-04-24 BR BR112021020957A patent/BR112021020957A2/pt unknown
- 2020-04-24 KR KR1020217038123A patent/KR20220004114A/ko active Pending
- 2020-04-24 MX MX2021012311A patent/MX2021012311A/es unknown
- 2020-04-24 EP EP20726600.8A patent/EP3958911A1/en active Pending
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2021
- 2021-08-19 ZA ZA2021/05975A patent/ZA202105975B/en unknown
- 2021-10-07 MX MX2025015023A patent/MX2025015023A/es unknown
- 2021-10-20 IL IL287438A patent/IL287438A/en unknown