JP2022522007A5 - - Google Patents

Info

Publication number
JP2022522007A5
JP2022522007A5 JP2021550149A JP2021550149A JP2022522007A5 JP 2022522007 A5 JP2022522007 A5 JP 2022522007A5 JP 2021550149 A JP2021550149 A JP 2021550149A JP 2021550149 A JP2021550149 A JP 2021550149A JP 2022522007 A5 JP2022522007 A5 JP 2022522007A5
Authority
JP
Japan
Application number
JP2021550149A
Other languages
Japanese (ja)
Other versions
JPWO2020176794A5 (https=
JP2022522007A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/020207 external-priority patent/WO2020176794A1/en
Publication of JP2022522007A publication Critical patent/JP2022522007A/ja
Publication of JPWO2020176794A5 publication Critical patent/JPWO2020176794A5/ja
Publication of JP2022522007A5 publication Critical patent/JP2022522007A5/ja
Priority to JP2025001193A priority Critical patent/JP2025061007A/ja
Pending legal-status Critical Current

Links

JP2021550149A 2019-02-27 2020-02-27 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法 Pending JP2022522007A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025001193A JP2025061007A (ja) 2019-02-27 2025-01-06 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962811411P 2019-02-27 2019-02-27
US62/811,411 2019-02-27
US202062967377P 2020-01-29 2020-01-29
US62/967,377 2020-01-29
PCT/US2020/020207 WO2020176794A1 (en) 2019-02-27 2020-02-27 Antibody-drug conjugates comprising anti-tm4sf1 antibodies and methods of using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025001193A Division JP2025061007A (ja) 2019-02-27 2025-01-06 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法

Publications (3)

Publication Number Publication Date
JP2022522007A JP2022522007A (ja) 2022-04-13
JPWO2020176794A5 JPWO2020176794A5 (https=) 2023-02-21
JP2022522007A5 true JP2022522007A5 (https=) 2023-02-21

Family

ID=72238523

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021550149A Pending JP2022522007A (ja) 2019-02-27 2020-02-27 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法
JP2025001193A Pending JP2025061007A (ja) 2019-02-27 2025-01-06 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025001193A Pending JP2025061007A (ja) 2019-02-27 2025-01-06 抗tm4sf1抗体を含む抗体薬物コンジュゲートおよびそれを使用する方法

Country Status (8)

Country Link
US (1) US12428477B2 (https=)
EP (1) EP3930767A4 (https=)
JP (2) JP2022522007A (https=)
CN (1) CN113874051A (https=)
AU (1) AU2020228060A1 (https=)
CA (1) CA3131391A1 (https=)
MX (1) MX2021010254A (https=)
WO (1) WO2020176794A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4313144A4 (en) * 2021-03-26 2025-08-20 Angiex Inc COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPY AGENTS AND METHODS OF USE THEREOF
AU2022245388A1 (en) * 2021-03-26 2023-10-05 Angiex, Inc. Maytansine-antibody conjugates and methods of using same
WO2023056069A1 (en) * 2021-09-30 2023-04-06 Angiex, Inc. Degrader-antibody conjugates and methods of using same
EP4423123A1 (en) * 2021-10-28 2024-09-04 Novartis AG Engineered fc variants
WO2025059546A1 (en) * 2023-09-13 2025-03-20 Trustees Of Tufts College Proteolysis-targeting chimera tumor vaccine

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US6548640B1 (en) 1986-03-27 2003-04-15 Btg International Limited Altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
US5571894A (en) 1991-02-05 1996-11-05 Ciba-Geigy Corporation Recombinant antibodies specific for a growth factor receptor
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
FI941572L (fi) 1991-10-07 1994-05-27 Oncologix Inc Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
AU675929B2 (en) 1992-02-06 1997-02-27 Curis, Inc. Biosynthetic binding protein for cancer marker
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
ES2375931T3 (es) 1997-12-05 2012-03-07 The Scripps Research Institute Humanización de anticuerpo murino.
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
ES2292236T3 (es) 1998-04-02 2008-03-01 Genentech, Inc. Variantes de anticuerpos y sus fragmentos.
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
HU230769B1 (hu) 1999-01-15 2018-03-28 Genentech Inc. Módosított effektor-funkciójú polipeptid-változatok
US7317091B2 (en) 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
AU2003225669A1 (en) 2002-09-26 2004-04-19 Pintex Pharmaceuticals, Inc. Pin1-modulating compounds and methods of use thereof
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
EP3263596A1 (en) 2002-12-16 2018-01-03 Genentech, Inc. Immunoglobulin variants and uses thereof
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
CN1961003B (zh) 2004-03-31 2013-03-27 健泰科生物技术公司 人源化抗TGF-β抗体
KR100891620B1 (ko) 2004-04-13 2009-04-02 에프. 호프만-라 로슈 아게 항-p-셀렉틴 항체
TWI309240B (en) 2004-09-17 2009-05-01 Hoffmann La Roche Anti-ox40l antibodies
DK1817340T3 (da) 2004-11-12 2012-08-13 Xencor Inc Fc-varianter med ændret binding til fcrn
EP1951890A4 (en) 2005-11-16 2009-06-24 Ambrx Inc PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
DK1968635T3 (en) 2005-12-14 2014-12-15 Ambrx Inc Compositions and Methods of, and uses of non-natural amino acids and polypeptides
AU2006332809A1 (en) 2005-12-30 2007-07-12 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
AU2007215566A1 (en) 2006-01-19 2007-08-23 Ambrx, Inc. Non-natural amino acid polypeptides having modulated immunogenicity
EP2079687A1 (en) 2006-12-18 2009-07-22 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
WO2008083346A1 (en) 2006-12-28 2008-07-10 Ambrx, Inc. Phenazine and quinoxaline substituted amino acids and polypeptides
ES2776406T3 (es) 2007-07-12 2020-07-30 Gitr Inc Terapias de combinación que emplean moléculas de enlazamiento a GITR
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
EP2230300A4 (en) * 2007-10-24 2012-08-08 Otsuka Chemical Holdings Co Ltd POLYPEPTIDE WITH IMPROVED EFFECTOR FUNCTION
RU2529951C2 (ru) 2007-12-26 2014-10-10 Ксенкор, Инк. ВАРИАНТЫ Fc С ИЗМЕНЕННЫМ СВЯЗЫВАНИЕМ C FcRn
HRP20160855T1 (hr) 2008-02-08 2016-09-23 Medimmune, Llc Anti-ifnar1 protutijela sa smanjenim afinitetom fc liganda
PE20110480A1 (es) 2008-09-26 2011-07-01 Ambrx Inc Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
EP2385114A4 (en) 2008-12-25 2012-08-08 Univ Tokyo CANCER TREATMENT DIAGNOSIS WITH ANTI-TM4SF20 ANTIBODY
AU2010270979B2 (en) * 2009-06-22 2015-04-23 Medimmune, Llc Engineered Fc regions for site-specific conjugation
SG10201602394QA (en) 2011-03-29 2016-05-30 Roche Glycart Ag Antibody FC Variants
WO2012145746A1 (en) 2011-04-21 2012-10-26 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for the treatment of neuromyelitis optica
KR102356286B1 (ko) 2011-05-27 2022-02-08 암브룩스, 인코포레이티드 비-천연 아미노산 연결된 돌라스타틴 유도체를 함유하는 조성물, 이를 수반하는 방법, 및 용도
KR20140037105A (ko) 2011-05-27 2014-03-26 암브룩스, 인코포레이티드 비-천연 아미노산 연결된 돌라스타틴 유도체를 함유하는 조성물, 이를 수반하는 방법, 및 용도
JP2014533659A (ja) 2011-10-24 2014-12-15 アッヴィ・インコーポレイテッド スクレロスチンに対するイムノバインダー
WO2014190441A1 (en) 2013-05-31 2014-12-04 Zymeworks Inc. Heteromultimers with reduced or silenced effector function
WO2015054427A1 (en) * 2013-10-10 2015-04-16 Beth Israel Deaconess Medical Center, Inc. Tm4sf1 binding proteins and methods of using same
KR102515248B1 (ko) 2013-11-22 2023-03-29 사브레 테라퓨틱스 엘엘씨 오토탁신 억제제 화합물
SG10201912986PA (en) 2014-05-28 2020-02-27 Agenus Inc Anti-gitr antibodies and methods of use thereof
JP6863900B2 (ja) * 2015-03-09 2021-04-21 ハイデルベルク ファルマ リサーチ ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規アマトキシン−抗体コンジュゲート
TWI812873B (zh) 2015-11-30 2023-08-21 美商輝瑞股份有限公司 用於部位專一性接合之抗體和抗體片段
CA3012196A1 (en) * 2016-02-02 2017-08-10 Meditope Biosciences, Inc. Anti-egfr antibody drug conjugate
MX2020002241A (es) 2017-08-28 2020-09-03 Angiex Inc Anticuerpos anti-tm4sf y métodos de uso de los mismos.
CA3103265A1 (en) 2018-06-12 2019-12-19 Angiex, Inc. Antibody-oligonucleotide conjugates
JP2023520371A (ja) 2020-03-27 2023-05-17 アンジーエックス・インコーポレーテッド デグレーダー分子-抗体コンジュゲートおよびその使用方法
WO2021222783A1 (en) 2020-05-01 2021-11-04 Angiex, Inc. Anti-tm4sf1 antibody drug conjugates and methods of using same
WO2022026915A2 (en) 2020-07-31 2022-02-03 Angiex, Inc. Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same
EP4204013A4 (en) 2020-08-26 2025-04-16 Angiex, Inc. ANTIMITOTIC TETRAPEPTIDE-ANTIBODY CONJUGATES AND METHODS OF USE THEREOF

Similar Documents

Publication Publication Date Title
BR112023005462A2 (https=)
BR112023012656A2 (https=)
BR112021014123A2 (https=)
BR112023009656A2 (https=)
BR112022009896A2 (https=)
JP2022522007A5 (https=)
BR112021017747A2 (https=)
BR112022024743A2 (https=)
BR112022026905A2 (https=)
BR112023011738A2 (https=)
BR112023004146A2 (https=)
BR112023006729A2 (https=)
BR102021015500A2 (https=)
BR112023016292A2 (https=)
BR112023011610A2 (https=)
BR112023011539A2 (https=)
BR112023008976A2 (https=)
BR102021016837A2 (https=)
BR102021016551A2 (https=)
BR102021016375A2 (https=)
BR102021016176A2 (https=)
BR102021016200A2 (https=)
BR102021015566A2 (https=)
BR102021015450A8 (https=)
BR102021015247A2 (https=)