JP2022521119A - 組織の灌流の増加における使用のためのイノシトールリン酸化合物 - Google Patents

組織の灌流の増加における使用のためのイノシトールリン酸化合物 Download PDF

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JP2022521119A
JP2022521119A JP2021532911A JP2021532911A JP2022521119A JP 2022521119 A JP2022521119 A JP 2022521119A JP 2021532911 A JP2021532911 A JP 2021532911A JP 2021532911 A JP2021532911 A JP 2021532911A JP 2022521119 A JP2022521119 A JP 2022521119A
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JPWO2020157362A5 (enExample
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バッシッシ，モハンマド・フィラス
ロカ，カロリーナ サルセド
ベスタルド，フアン ペレロ
レイネス，ミゲル・ダビド フェレール
フェレール，マリア・デル・マール ペレス
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サニフィット・セラピューティクス・ソシエダッド・アノニマ
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Publication of JP2022521119A publication Critical patent/JP2022521119A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021532911A 2019-01-30 2020-01-30 組織の灌流の増加における使用のためのイノシトールリン酸化合物 Pending JP2022521119A (ja)

Priority Applications (1)

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JP2024158993A JP2024175025A (ja) 2019-01-30 2024-09-13 組織の灌流の増加における使用のためのイノシトールリン酸化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19382061.0 2019-01-30
EP19382061 2019-01-30
US201962913259P 2019-10-10 2019-10-10
US62/913,259 2019-10-10
PCT/ES2020/070070 WO2020157362A1 (en) 2019-01-30 2020-01-30 Inositol phosphate compounds for use in increasing tissular perfusion

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JP2024158993A Division JP2024175025A (ja) 2019-01-30 2024-09-13 組織の灌流の増加における使用のためのイノシトールリン酸化合物

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JP2022521119A true JP2022521119A (ja) 2022-04-06
JPWO2020157362A5 JPWO2020157362A5 (enExample) 2022-09-14

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JP2021532911A Pending JP2022521119A (ja) 2019-01-30 2020-01-30 組織の灌流の増加における使用のためのイノシトールリン酸化合物
JP2024158993A Pending JP2024175025A (ja) 2019-01-30 2024-09-13 組織の灌流の増加における使用のためのイノシトールリン酸化合物

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US (2) US20220000889A1 (enExample)
EP (1) EP3917535A1 (enExample)
JP (2) JP2022521119A (enExample)
KR (1) KR20210148078A (enExample)
CN (1) CN113365636A (enExample)
AU (1) AU2020213713B2 (enExample)
BR (1) BR112021014897A2 (enExample)
CA (1) CA3130735A1 (enExample)
IL (1) IL285084A (enExample)
MX (1) MX2021008966A (enExample)
WO (1) WO2020157362A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230110552A (ko) * 2020-11-20 2023-07-24 비포르 (인터내셔날) 아게 석회화 관련 신장 질환 치료를 위한 이노시톨 헥사키스포스페이트 유사체
WO2024047037A1 (en) 2022-08-30 2024-03-07 ETH Zürich Compositions for parenteral sustained release delivery of hydrophilic drugs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003507430A (ja) * 1999-08-25 2003-02-25 ジーエムピー カンパニーズ，インコーポレーテッド 哺乳動物中で酸素運搬を向上する薬剤
JP2016514119A (ja) * 2013-03-15 2016-05-19 ラボラトリス サニフィット，エセ．エレ． 腎不全を患っている患者におけるｃ−ｏ−ｐ結合を含む誘導体の使用
WO2017098047A1 (en) * 2015-12-11 2017-06-15 ETH Zürich Inositol derivatives for use in pathological crystallization

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5007790A (en) 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5582837A (en) 1992-03-25 1996-12-10 Depomed, Inc. Alkyl-substituted cellulose-based sustained-release oral drug dosage forms
JPH07507059A (ja) 1992-03-25 1995-08-03 デポムド　システムズ，インコーポレイテッド アルキル置換セルロースをベースとする持続放出性経口薬剤投与剤形
AU3290397A (en) 1996-06-10 1998-01-07 Depomed, Inc. Gastric-retentive oral controlled drug delivery system with enhanced retention properties
US5972389A (en) 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
PT998271E (pt) 1997-06-06 2005-10-31 Depomed Inc Formas de dosagem oral de farmacos com retencao gastrica para a libertacao controlada de farmacos altamente soluveis
US6635280B2 (en) 1997-06-06 2003-10-21 Depomed, Inc. Extending the duration of drug release within the stomach during the fed mode
AU7995600A (en) * 1999-10-05 2001-05-10 Theramed, Inc. Compositions and methods for the incorporation of chemical substances into cells
EP1242057A2 (en) 1999-11-02 2002-09-25 DepoMed, Inc. Pharmacological inducement of the fed mode for enhanced drug administration to the stomach
PT1251832E (pt) 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
AU2001279118A1 (en) * 2000-08-01 2002-02-13 Gmp Companies, Inc. Ammonium salts of inositol hexaphosphate and uses thereof
WO2002009723A2 (en) * 2000-08-01 2002-02-07 Gmp Companies, Inc. Ammonium salts of hemoglobin allosteric effectors, and uses thereof
US6451808B1 (en) 2000-10-17 2002-09-17 Depomed, Inc. Inhibition of emetic effect of metformin with 5-HT3 receptor antagonists
JP3678144B2 (ja) 2000-12-22 2005-08-03 ウシオ電機株式会社 フィルム回路基板の周辺露光装置
US20030031711A1 (en) 2001-05-29 2003-02-13 Fara John W. Method of treating gastroesophageal reflux disease and nocturnal acid breakthrough
US20030091630A1 (en) 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
EP1438027A1 (en) 2001-10-25 2004-07-21 DepoMed, Inc. Methods of treatment using a gastric retained losartan dosage
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
ES2232302B1 (es) 2003-11-07 2006-08-01 Universitat De Les Illes Balears Myo-inositol hexafosfato para uso topico.
ES2288126B2 (es) 2006-06-01 2009-07-06 Universitat De Les Illes Balears Utilizacion de fitato como agente inhibidor de la disolucion de cristales de sales calcicas para la prevencion o tratamiento de la osteoporosis.
ES2332636B1 (es) 2008-08-06 2011-02-10 Universitat De Les Illes Balears Composicion de liquido de dialisis.
JP5766884B2 (ja) 2011-09-29 2015-08-19 エーテーハー・チューリッヒＥＴＨＺｕｒｉｃｈ クロストリジウム・ディフィシル感染症の治療に使用するための医薬化合物
EP2579036A1 (en) 2011-10-06 2013-04-10 Laboratorios Sanifit, S.L. Method for the direct detection and/or quantification of at least one compound with a molecular weight of at least 200
EP3386994B1 (en) 2015-12-11 2019-12-11 ETH Zürich 4,6-di-(o-thiophosphate)-inositol-1,2,3,5-tetra-o-sulfate for c. difficile infection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003507430A (ja) * 1999-08-25 2003-02-25 ジーエムピー カンパニーズ，インコーポレーテッド 哺乳動物中で酸素運搬を向上する薬剤
JP2016514119A (ja) * 2013-03-15 2016-05-19 ラボラトリス サニフィット，エセ．エレ． 腎不全を患っている患者におけるｃ−ｏ−ｐ結合を含む誘導体の使用
WO2017098047A1 (en) * 2015-12-11 2017-06-15 ETH Zürich Inositol derivatives for use in pathological crystallization

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NUTRIENTS, vol. Vol.10, 652, JPN6024040551, 2018, pages 1 - 17, ISSN: 0005429847 *
THE ANNALS OF THORACIC SURGERY, vol. 52, no. 4, JPN6023037062, 1991, pages 908 - 912, ISSN: 0005429845 *
日本血管外科学会雑誌, vol. 25, JPN6024017486, 2016, pages 359 - 365, ISSN: 0005429846 *
日衛誌, vol. 70, JPN6024040550, 2015, pages 211 - 219, ISSN: 0005429848 *

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Publication number Publication date
KR20210148078A (ko) 2021-12-07
MX2021008966A (es) 2021-11-04
AU2020213713A1 (en) 2021-07-22
EP3917535A1 (en) 2021-12-08
US20220000889A1 (en) 2022-01-06
IL285084A (en) 2021-09-30
WO2020157362A1 (en) 2020-08-06
CA3130735A1 (en) 2020-08-06
US20230248749A1 (en) 2023-08-10
JP2024175025A (ja) 2024-12-17
CN113365636A (zh) 2021-09-07
AU2020213713B2 (en) 2025-08-21
BR112021014897A2 (pt) 2021-09-28

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