JP2022516510A - ウステキヌマブの生成方法 - Google Patents
ウステキヌマブの生成方法 Download PDFInfo
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- JP2022516510A JP2022516510A JP2021538215A JP2021538215A JP2022516510A JP 2022516510 A JP2022516510 A JP 2022516510A JP 2021538215 A JP2021538215 A JP 2021538215A JP 2021538215 A JP2021538215 A JP 2021538215A JP 2022516510 A JP2022516510 A JP 2022516510A
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- ustekinumab
- glycans
- cells
- glycan
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Images
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US201862786821P | 2018-12-31 | 2018-12-31 | |
| US62/786,821 | 2018-12-31 | ||
| PCT/US2019/067916 WO2020142275A1 (en) | 2018-12-31 | 2019-12-20 | Methods of producing ustekinumab |
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| JP2022516510A true JP2022516510A (ja) | 2022-02-28 |
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| MX (1) | MX2021008030A (es) |
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| US11719704B2 (en) | 2015-12-30 | 2023-08-08 | Momenta Pharmaceuticals, Inc. | Methods related to biologics |
| CN112852743B (zh) * | 2021-01-25 | 2021-11-02 | 江苏荃信生物医药有限公司 | 用于生产乌司奴单抗的生物类似药的细胞株及生产方法 |
| WO2024092203A1 (en) * | 2022-10-28 | 2024-05-02 | Amgen Inc. | Compositions of anti-interleukin 12/interleukin 23 antibody |
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| NZ593816A (en) * | 2009-01-22 | 2012-11-30 | Momenta Pharmaceuticals Inc | Galactose-alpha-1, 3-galactose-containing n-glycans in glycoprotein products derived from cho cells |
| US20140271622A1 (en) * | 2013-03-14 | 2014-09-18 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| WO2014149935A1 (en) * | 2013-03-15 | 2014-09-25 | Janssen Biotech, Inc. | Manufacturing methods to control c-terminal lysine, galactose and sialic acid content in recombinant proteins |
| JP6797458B2 (ja) * | 2014-01-29 | 2020-12-09 | エルジー・ケム・リミテッド | 培養培地の最適化により組換えタンパク質のガラクトシル化を調節する方法 |
| WO2016089919A1 (en) * | 2014-12-01 | 2016-06-09 | Amgen Inc. | Process for manipulating the level of glycan content of a glycoprotein |
| CN105779394B (zh) * | 2015-03-20 | 2020-03-24 | 广东东阳光药业有限公司 | 一种降低抗体酸性峰含量和改良抗体糖型的细胞培养方法 |
| CN109072273B (zh) * | 2016-05-10 | 2022-04-15 | 阿雷斯贸易股份有限公司 | 使用全乙酰基半乳糖调节重组蛋白的蛋白质半乳糖基化概况的方法 |
| US20200347126A1 (en) * | 2016-08-03 | 2020-11-05 | Fyb 202 Project Gmbh | Production of Biosimilar Ustekinumab In CHO Cells |
| US20200199525A1 (en) * | 2017-06-08 | 2020-06-25 | Polpharma Biologics S.A. | Improved Methods of Cell Culture |
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| KR20210131323A (ko) | 2021-11-02 |
| EP3906257A4 (en) | 2022-09-14 |
| CA3125443A1 (en) | 2020-07-09 |
| IL284374A (en) | 2021-08-31 |
| EP3906257A1 (en) | 2021-11-10 |
| US20220081479A1 (en) | 2022-03-17 |
| BR112021012973A2 (pt) | 2021-09-14 |
| WO2020142275A1 (en) | 2020-07-09 |
| US20220033487A1 (en) | 2022-02-03 |
| AU2019419372A1 (en) | 2021-07-08 |
| EA202191840A1 (ru) | 2021-09-03 |
| MX2021008030A (es) | 2021-08-05 |
| CN113474366A (zh) | 2021-10-01 |
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