MX2021008030A - Metodos para producir ustekinumab. - Google Patents
Metodos para producir ustekinumab.Info
- Publication number
- MX2021008030A MX2021008030A MX2021008030A MX2021008030A MX2021008030A MX 2021008030 A MX2021008030 A MX 2021008030A MX 2021008030 A MX2021008030 A MX 2021008030A MX 2021008030 A MX2021008030 A MX 2021008030A MX 2021008030 A MX2021008030 A MX 2021008030A
- Authority
- MX
- Mexico
- Prior art keywords
- ustekinumab
- methods
- producing
- glycans
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describen métodos para fabricar un producto de ustekinumab con un nivel objetivo de uno o más glicanos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862786821P | 2018-12-31 | 2018-12-31 | |
| PCT/US2019/067916 WO2020142275A1 (en) | 2018-12-31 | 2019-12-20 | Methods of producing ustekinumab |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021008030A true MX2021008030A (es) | 2021-08-05 |
Family
ID=71407091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021008030A MX2021008030A (es) | 2018-12-31 | 2019-12-20 | Metodos para producir ustekinumab. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20220033487A1 (es) |
| EP (1) | EP3906257A4 (es) |
| JP (1) | JP2022516510A (es) |
| KR (1) | KR20210131323A (es) |
| CN (1) | CN113474366A (es) |
| AU (1) | AU2019419372A1 (es) |
| BR (1) | BR112021012973A2 (es) |
| CA (1) | CA3125443A1 (es) |
| EA (1) | EA202191840A1 (es) |
| IL (1) | IL284374A (es) |
| MX (1) | MX2021008030A (es) |
| WO (1) | WO2020142275A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11719704B2 (en) | 2015-12-30 | 2023-08-08 | Momenta Pharmaceuticals, Inc. | Methods related to biologics |
| CN112852743B (zh) * | 2021-01-25 | 2021-11-02 | 江苏荃信生物医药有限公司 | 用于生产乌司奴单抗的生物类似药的细胞株及生产方法 |
| WO2024092203A1 (en) * | 2022-10-28 | 2024-05-02 | Amgen Inc. | Compositions of anti-interleukin 12/interleukin 23 antibody |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009338190C1 (en) * | 2009-01-22 | 2014-07-17 | Momenta Pharmaceuticals, Inc. | Galactose-alpha-1, 3-galactose-containing N-glycans in glycoprotein products derived from CHO cells |
| US20140271622A1 (en) * | 2013-03-14 | 2014-09-18 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| CA2907140A1 (en) * | 2013-03-15 | 2014-09-25 | Janssen Biotech, Inc. | Manufacturing methods to control c-terminal lysine, galactose and sialic acid content in recombinant proteins |
| JP6797458B2 (ja) * | 2014-01-29 | 2020-12-09 | エルジー・ケム・リミテッド | 培養培地の最適化により組換えタンパク質のガラクトシル化を調節する方法 |
| WO2016089919A1 (en) * | 2014-12-01 | 2016-06-09 | Amgen Inc. | Process for manipulating the level of glycan content of a glycoprotein |
| CN105779394B (zh) * | 2015-03-20 | 2020-03-24 | 广东东阳光药业有限公司 | 一种降低抗体酸性峰含量和改良抗体糖型的细胞培养方法 |
| US11118208B2 (en) * | 2016-05-10 | 2021-09-14 | Ares Trading S.A. | Methods for modulating protein galactosylation profiles of recombinant proteins using peracetyl galactose |
| EP3493843A1 (en) * | 2016-08-03 | 2019-06-12 | FYB 202 Project GmbH | Production of biosimilar ustekinumab in cho cells |
| US20200199525A1 (en) * | 2017-06-08 | 2020-06-25 | Polpharma Biologics S.A. | Improved Methods of Cell Culture |
-
2019
- 2019-12-20 MX MX2021008030A patent/MX2021008030A/es unknown
- 2019-12-20 US US17/419,480 patent/US20220033487A1/en active Pending
- 2019-12-20 AU AU2019419372A patent/AU2019419372A1/en active Pending
- 2019-12-20 EA EA202191840A patent/EA202191840A1/ru unknown
- 2019-12-20 JP JP2021538215A patent/JP2022516510A/ja active Pending
- 2019-12-20 KR KR1020217024320A patent/KR20210131323A/ko unknown
- 2019-12-20 BR BR112021012973-1A patent/BR112021012973A2/pt unknown
- 2019-12-20 US US17/419,541 patent/US20220081479A1/en active Pending
- 2019-12-20 CN CN201980087512.7A patent/CN113474366A/zh active Pending
- 2019-12-20 CA CA3125443A patent/CA3125443A1/en active Pending
- 2019-12-20 EP EP19907232.3A patent/EP3906257A4/en active Pending
- 2019-12-20 WO PCT/US2019/067916 patent/WO2020142275A1/en unknown
-
2021
- 2021-06-24 IL IL284374A patent/IL284374A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3125443A1 (en) | 2020-07-09 |
| EP3906257A4 (en) | 2022-09-14 |
| US20220081479A1 (en) | 2022-03-17 |
| CN113474366A (zh) | 2021-10-01 |
| WO2020142275A1 (en) | 2020-07-09 |
| IL284374A (en) | 2021-08-31 |
| EP3906257A1 (en) | 2021-11-10 |
| BR112021012973A2 (pt) | 2021-09-14 |
| JP2022516510A (ja) | 2022-02-28 |
| AU2019419372A1 (en) | 2021-07-08 |
| EA202191840A1 (ru) | 2021-09-03 |
| KR20210131323A (ko) | 2021-11-02 |
| US20220033487A1 (en) | 2022-02-03 |
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