JP2022514148A5 - - Google Patents

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Publication number
JP2022514148A5
JP2022514148A5 JP2021518202A JP2021518202A JP2022514148A5 JP 2022514148 A5 JP2022514148 A5 JP 2022514148A5 JP 2021518202 A JP2021518202 A JP 2021518202A JP 2021518202 A JP2021518202 A JP 2021518202A JP 2022514148 A5 JP2022514148 A5 JP 2022514148A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
cdr
bispecific binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2021518202A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022514148A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2019/038750 external-priority patent/WO2020071365A1/en
Publication of JP2022514148A publication Critical patent/JP2022514148A/ja
Publication of JP2022514148A5 publication Critical patent/JP2022514148A5/ja
Withdrawn legal-status Critical Current

Links

JP2021518202A 2018-10-02 2019-10-01 シンデカン-1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質 Withdrawn JP2022514148A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862740337P 2018-10-02 2018-10-02
US62/740,337 2018-10-02
PCT/JP2019/038750 WO2020071365A1 (en) 2018-10-02 2019-10-01 Bi-specific binding agents targeting syndecan-1 and fibroblast growth factor receptor

Publications (2)

Publication Number Publication Date
JP2022514148A JP2022514148A (ja) 2022-02-10
JP2022514148A5 true JP2022514148A5 (https=) 2022-07-28

Family

ID=70055592

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021518202A Withdrawn JP2022514148A (ja) 2018-10-02 2019-10-01 シンデカン-1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質

Country Status (15)

Country Link
US (1) US20220249679A1 (https=)
EP (1) EP3861117A4 (https=)
JP (1) JP2022514148A (https=)
KR (1) KR20210070307A (https=)
CN (1) CN113039271A (https=)
AR (1) AR116563A1 (https=)
AU (1) AU2019353367A1 (https=)
BR (1) BR112021005465A2 (https=)
CA (1) CA3107423A1 (https=)
IL (1) IL281929A (https=)
MX (1) MX2021003861A (https=)
PH (1) PH12021500023A1 (https=)
SG (1) SG11202103143UA (https=)
TW (1) TW202028459A (https=)
WO (1) WO2020071365A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220148235A (ko) * 2020-02-28 2022-11-04 젠자임 코포레이션 최적화된 약물 접합을 위한 변형된 결합 폴리펩티드

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005302083A1 (en) * 2004-11-04 2006-05-11 Fibron Limited Treatment of B-cell malignancies
CN101965366B (zh) * 2007-12-26 2016-04-27 生物测试股份公司 靶向cd138的免疫缀合物及其应用
WO2012158818A2 (en) * 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
CA2855566A1 (en) * 2011-12-02 2013-06-06 Ibc Pharmaceuticals, Inc. Multivalent antibody complexes targeting igf-1r show potent toxicity against solid tumors
KR20140100571A (ko) * 2011-12-08 2014-08-14 바이오테스트 아게 Cd138을 타겟팅하는 면역접합체의 용도
US10633451B2 (en) * 2012-02-03 2020-04-28 Hoffmann-La Roche Inc. Bispecific antibody molecules with antigen-transfected T-cells and their use in medicine
HK1211208A1 (zh) * 2012-08-22 2016-05-20 Immunogen, Inc. 細胞毒性苯並二氮呯衍生物
US9803021B2 (en) * 2012-12-07 2017-10-31 The Regents Of The University Of California CD138-targeted interferon demonstrates potent apoptotic and anti-tumor activities
CA2942546C (en) * 2014-03-17 2022-11-22 Mitsubishi Tanabe Pharma Corporation Antibody-fynomer conjugates
RU2611685C2 (ru) * 2015-07-20 2017-02-28 Илья Владимирович Духовлинов Гуманизированное моноклональное антитело, специфичное к синдекану-1
KR102642385B1 (ko) * 2017-02-06 2024-03-04 오리오니스 바이오사이언시스 엔브이 표적화된 키메라 단백질 및 이의 용도
US10722589B2 (en) * 2017-04-03 2020-07-28 Covagen Ag FGFR3 binding molecules
WO2018199176A1 (en) * 2017-04-26 2018-11-01 Mitsubishi Tanabe Pharma Corporation Syndecan-1 (cd138) binding agents and uses thereof
JP2021165268A (ja) * 2020-04-07 2021-10-14 田辺三菱製薬株式会社 シンデカン−1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質を含む医薬組成物

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