JP2022514148A5 - - Google Patents

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Publication number
JP2022514148A5
JP2022514148A5 JP2021518202A JP2021518202A JP2022514148A5 JP 2022514148 A5 JP2022514148 A5 JP 2022514148A5 JP 2021518202 A JP2021518202 A JP 2021518202A JP 2021518202 A JP2021518202 A JP 2021518202A JP 2022514148 A5 JP2022514148 A5 JP 2022514148A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
cdr
bispecific binding
Prior art date
Application number
JP2021518202A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2020071365A5 (https=
JP2022514148A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2019/038750 external-priority patent/WO2020071365A1/en
Publication of JP2022514148A publication Critical patent/JP2022514148A/ja
Publication of JPWO2020071365A5 publication Critical patent/JPWO2020071365A5/ja
Publication of JP2022514148A5 publication Critical patent/JP2022514148A5/ja
Withdrawn legal-status Critical Current

Links

JP2021518202A 2018-10-02 2019-10-01 シンデカン-1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質 Withdrawn JP2022514148A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862740337P 2018-10-02 2018-10-02
US62/740,337 2018-10-02
PCT/JP2019/038750 WO2020071365A1 (en) 2018-10-02 2019-10-01 Bi-specific binding agents targeting syndecan-1 and fibroblast growth factor receptor

Publications (3)

Publication Number Publication Date
JP2022514148A JP2022514148A (ja) 2022-02-10
JPWO2020071365A5 JPWO2020071365A5 (https=) 2022-07-28
JP2022514148A5 true JP2022514148A5 (https=) 2022-07-28

Family

ID=70055592

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021518202A Withdrawn JP2022514148A (ja) 2018-10-02 2019-10-01 シンデカン-1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質

Country Status (15)

Country Link
US (1) US20220249679A1 (https=)
EP (1) EP3861117A4 (https=)
JP (1) JP2022514148A (https=)
KR (1) KR20210070307A (https=)
CN (1) CN113039271A (https=)
AR (1) AR116563A1 (https=)
AU (1) AU2019353367A1 (https=)
BR (1) BR112021005465A2 (https=)
CA (1) CA3107423A1 (https=)
IL (1) IL281929A (https=)
MX (1) MX2021003861A (https=)
PH (1) PH12021500023A1 (https=)
SG (1) SG11202103143UA (https=)
TW (1) TW202028459A (https=)
WO (1) WO2020071365A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4110404A1 (en) * 2020-02-28 2023-01-04 Genzyme Corporation Modified binding polypeptides for optimized drug conjugation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006048877A2 (en) * 2004-11-04 2006-05-11 Fibron Limited Treatment of b-cell malignancies with fgfr3 inhibitors
ES2526433T3 (es) * 2007-12-26 2015-01-12 Biotest Ag Inmunoconjugados dirigidos a CD138 y usos de los mismos
WO2012158818A2 (en) * 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
WO2013082254A1 (en) * 2011-12-02 2013-06-06 Ibc Pharmaceuticals, Inc. Multivalent antibody complexes targeting igf-1r show potent toxicity against solid tumors
MX358680B (es) * 2011-12-08 2018-08-31 Biotest Ag Usos de inmunoconjugados dirigidos a cd138.
CA2861031C (en) * 2012-02-03 2022-10-25 Carole BOURQUIN Bispecific antibody molecules with antigen-transfected t-cells and their use in medicine
HK1211208A1 (zh) * 2012-08-22 2016-05-20 Immunogen, Inc. 細胞毒性苯並二氮呯衍生物
US9803021B2 (en) * 2012-12-07 2017-10-31 The Regents Of The University Of California CD138-targeted interferon demonstrates potent apoptotic and anti-tumor activities
US10323095B2 (en) * 2014-03-17 2019-06-18 Mitsubishi Tanabe Pharma Corporation Antibody-fynomer conjugates
RU2611685C2 (ru) * 2015-07-20 2017-02-28 Илья Владимирович Духовлинов Гуманизированное моноклональное антитело, специфичное к синдекану-1
EP3577133A1 (en) * 2017-02-06 2019-12-11 Orionis Biosciences NV Targeted chimeric proteins and uses thereof
US10722589B2 (en) * 2017-04-03 2020-07-28 Covagen Ag FGFR3 binding molecules
CN110691793A (zh) * 2017-04-26 2020-01-14 田边三菱制药株式会社 黏结蛋白聚糖-1(cd138)结合剂及其用
JP2021165268A (ja) * 2020-04-07 2021-10-14 田辺三菱製薬株式会社 シンデカン−1および線維芽細胞増殖因子受容体を標的とする二重特異性結合物質を含む医薬組成物

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