JP2021520195A5 - - Google Patents

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Publication number
JP2021520195A5
JP2021520195A5 JP2020554097A JP2020554097A JP2021520195A5 JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5 JP 2020554097 A JP2020554097 A JP 2020554097A JP 2020554097 A JP2020554097 A JP 2020554097A JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
sequence described
cdr2
Prior art date
Application number
JP2020554097A
Other languages
English (en)
Japanese (ja)
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JP7477457B2 (ja
JP2021520195A (ja
JPWO2019195136A5 (https=
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Priority claimed from PCT/US2019/025123 external-priority patent/WO2019195136A1/en
Publication of JP2021520195A publication Critical patent/JP2021520195A/ja
Publication of JP2021520195A5 publication Critical patent/JP2021520195A5/ja
Publication of JPWO2019195136A5 publication Critical patent/JPWO2019195136A5/ja
Priority to JP2024019502A priority Critical patent/JP2024056851A/ja
Application granted granted Critical
Publication of JP7477457B2 publication Critical patent/JP7477457B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020554097A 2018-04-03 2019-04-01 C3結合薬及びその使用方法 Active JP7477457B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024019502A JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652253P 2018-04-03 2018-04-03
US62/652,253 2018-04-03
PCT/US2019/025123 WO2019195136A1 (en) 2018-04-03 2019-04-01 C3-binding agents and methods of use thereof

Related Child Applications (1)

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JP2024019502A Division JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Publications (4)

Publication Number Publication Date
JP2021520195A JP2021520195A (ja) 2021-08-19
JP2021520195A5 true JP2021520195A5 (https=) 2022-04-08
JPWO2019195136A5 JPWO2019195136A5 (https=) 2022-04-08
JP7477457B2 JP7477457B2 (ja) 2024-05-01

Family

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JP2020554097A Active JP7477457B2 (ja) 2018-04-03 2019-04-01 C3結合薬及びその使用方法
JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Family Applications After (1)

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JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Country Status (18)

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US (3) US11136381B2 (https=)
EP (1) EP3790897A1 (https=)
JP (2) JP7477457B2 (https=)
KR (1) KR20200138290A (https=)
CN (1) CN112105638A (https=)
AR (1) AR117565A1 (https=)
AU (1) AU2019248557A1 (https=)
BR (1) BR112020019907A2 (https=)
CA (1) CA3093356A1 (https=)
CL (2) CL2020002522A1 (https=)
CO (1) CO2020013468A2 (https=)
IL (1) IL277404A (https=)
MX (1) MX2020010323A (https=)
PE (1) PE20212132A1 (https=)
PH (1) PH12020500664A1 (https=)
SG (1) SG11202008897SA (https=)
TW (1) TWI833742B (https=)
WO (1) WO2019195136A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019195136A1 (en) 2018-04-03 2019-10-10 Ngm Biopharmaceuticals, Inc. C3-binding agents and methods of use thereof
WO2021226442A2 (en) * 2020-05-08 2021-11-11 Ngm Biopharmaceuticals, Inc. Therapeutic uses of c3-binding agents
US20230381269A1 (en) * 2020-09-21 2023-11-30 Apellis Pharmaceuticals, Inc. Methods of treating eye disorders
CN116848136A (zh) * 2021-02-12 2023-10-03 勃林格殷格翰国际有限公司 补体c3抗原结合蛋白
IL313655A (en) 2021-12-22 2024-08-01 Boehringer Ingelheim Int Anti-C3 antibodies and their antigen-binding fragments and their uses for the treatment of eyes or eye diseases
WO2024086555A1 (en) 2022-10-17 2024-04-25 Ngm Biopharmaceuticals, Inc. Uses of anti-c3 antibodies
CN117447601B (zh) * 2023-12-22 2024-03-08 北京索莱宝科技有限公司 猪IgM的抗体、抗体组合物及其应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01002580A (es) * 1998-09-10 2002-04-08 Univ Virginia Anticuerpos para c3b(1) para el suministro de agentes de diagnostico y terapeuticos para celulas cancerosas.
WO2004031240A1 (en) * 2002-10-04 2004-04-15 Stichting Sanquin Bloedvoorziening Monoclonal antibody anti-c3-2 directed against the third component of complement (c3) and its use in methods to inhibit complement activation
US7816497B2 (en) 2002-10-30 2010-10-19 University Of Kentucky Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
WO2004041867A2 (en) * 2002-11-08 2004-05-21 Ablynx N.V. Camelidae antibodies against imminoglobulin e and use thereof for the treatment of allergic disorders
US20090004183A1 (en) 2004-07-23 2009-01-01 Taylor Ronald P Compositions and Methods for Regulating the Alternative Pathway of Complement
WO2006083533A2 (en) 2005-01-14 2006-08-10 The Regents Of The University Of California Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
EP3299027A1 (en) 2005-11-04 2018-03-28 Genentech, Inc. Use of complement pathway inhibitors to treat ocular diseases
PL2148691T3 (pl) 2007-02-05 2015-12-31 Apellis Pharmaceuticals Inc Analogi kompstatyny do stosowania w leczeniu stanów zapalnych układu oddechowego
US9745367B2 (en) 2007-03-23 2017-08-29 Novelmed Theraputics, Inc. Alternative pathway specific antibodies for treating arthritis
US8192742B2 (en) 2007-03-23 2012-06-05 NovelMed Therapeutics Method of inhibiting complement activation with human anti-factor C3 antibodies and use thereof
BRPI0812767A2 (pt) 2007-06-07 2014-12-02 Genentech Inc Anticorpos para c3b e métodos para prevenção e tratamento de distúrbios associados ao complemento
US20100291106A1 (en) * 2009-05-06 2010-11-18 Novartis Ag Compositions and methods for antibodies targeting complement protein c3b
RU2548807C2 (ru) 2009-05-20 2015-04-20 Торэй Индастриз, Инк. Пептиды, проникающие в клетку
US9291622B2 (en) 2009-05-21 2016-03-22 Apellis Pharmaceuticals, Inc. Complement assays and uses thereof
US20130177567A1 (en) 2010-05-18 2013-07-11 Sydansk Universitet Novel c3c epitope, antibodies binding thereto, and use thereof
US9815890B2 (en) 2010-06-22 2017-11-14 The Regents Of The University Of Colorado, A Body Corporate Antibodies to the C3d fragment of complement component 3
US9243060B2 (en) 2012-04-03 2016-01-26 Novelmed Therapeutics, Inc. Humanized anti-factor C3b antibodies and uses thereof
WO2015099838A2 (en) 2013-12-24 2015-07-02 Novelmed Therapeutics, Inc. Compositions and methods of treating ocular diseases
SG10202003996YA (en) 2014-05-05 2020-06-29 Regeneron Pharma Humanized c5 and c3 animals
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
AU2015360502A1 (en) * 2014-12-10 2017-06-29 Regents Of The University Of Minnesota Genetically modified cells, tissues, and organs for treating disease
US20180346531A1 (en) 2015-09-15 2018-12-06 Regents Of The University Of California Compositions and methods for delivering biotherapeutics
EP3359555B1 (en) 2015-10-07 2023-12-20 Apellis Pharmaceuticals, Inc. Dosing regimens
RU2630647C1 (ru) * 2016-05-27 2017-09-11 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства ГУМАНИЗИРОВАННОЕ АНТИТЕЛО К КОНФОРМАЦИОННОМУ ЭПИТОПУ С3 КОМПОНЕНТА КОМПЛЕМЕНТА ЧЕЛОВЕКА, ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), ЭКСПРЕССИОННЫЙ ВЕКТОР, СОДЕРЖАЩИЙ ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), И ШТАММ КЛЕТОК ЯИЧНИКОВ КИТАЙСКОГО ХОМЯЧКА CHO-humC34-ПРОДУЦЕНТ ДАННОГО ГУМАНИЗИРОВАННОГО АНТИТЕЛА
EP3654941A1 (en) 2017-07-17 2020-05-27 Keith Roizman Topical delivery of therapeutic agents comprising cell-penetrating peptides for use for the treatment of age-related macular degeneration and other eye diseases
WO2019195136A1 (en) 2018-04-03 2019-10-10 Ngm Biopharmaceuticals, Inc. C3-binding agents and methods of use thereof

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