JP2022513331A5 - - Google Patents

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Publication number
JP2022513331A5
JP2022513331A5 JP2021543565A JP2021543565A JP2022513331A5 JP 2022513331 A5 JP2022513331 A5 JP 2022513331A5 JP 2021543565 A JP2021543565 A JP 2021543565A JP 2021543565 A JP2021543565 A JP 2021543565A JP 2022513331 A5 JP2022513331 A5 JP 2022513331A5
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JP
Japan
Prior art keywords
seq
chain variable
antibody according
variable domain
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021543565A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022513331A (ja
JP7610515B2 (ja
Filing date
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Application filed filed Critical
Priority claimed from PCT/EP2019/076772 external-priority patent/WO2020070225A1/en
Publication of JP2022513331A publication Critical patent/JP2022513331A/ja
Publication of JP2022513331A5 publication Critical patent/JP2022513331A5/ja
Application granted granted Critical
Publication of JP7610515B2 publication Critical patent/JP7610515B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021543565A 2018-10-04 2019-10-02 ヒト化抗N短縮型アミロイドβモノクローナル抗体 Active JP7610515B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201816210 2018-10-04
GB1816210.7 2018-10-04
PCT/EP2019/076772 WO2020070225A1 (en) 2018-10-04 2019-10-02 Humanised anti-n-truncated amyloid beta monoclonal antibody

Publications (3)

Publication Number Publication Date
JP2022513331A JP2022513331A (ja) 2022-02-07
JP2022513331A5 true JP2022513331A5 (enExample) 2022-10-06
JP7610515B2 JP7610515B2 (ja) 2025-01-08

Family

ID=68136417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021543565A Active JP7610515B2 (ja) 2018-10-04 2019-10-02 ヒト化抗N短縮型アミロイドβモノクローナル抗体

Country Status (12)

Country Link
US (1) US12297261B2 (enExample)
EP (1) EP3861023A1 (enExample)
JP (1) JP7610515B2 (enExample)
KR (1) KR102862077B1 (enExample)
CN (1) CN113056480B (enExample)
AU (1) AU2019354714B9 (enExample)
BR (1) BR112021006153A2 (enExample)
EA (1) EA202190954A1 (enExample)
IL (1) IL281979B2 (enExample)
MX (1) MX2021003867A (enExample)
SG (1) SG11202102765RA (enExample)
WO (1) WO2020070225A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
KR20210124308A (ko) 2019-01-30 2021-10-14 트루바인딩 아이엔씨. 항-gal3 항체 및 이의 용도
CN115698060A (zh) 2020-03-10 2023-02-03 生命爱科 环肽
MX2022014786A (es) 2020-05-26 2023-01-16 Truebinding Inc Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3.
WO2024133925A1 (en) 2022-12-22 2024-06-27 Bioarctic Ab Antibody which binds to abetape3
WO2025262228A1 (en) 2024-06-20 2025-12-26 Bioarctic Ab Bispecific binding molecule

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US474900A (en) 1892-05-17 William byrnes
US4704362A (en) 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
EP0279582A3 (en) 1987-02-17 1989-10-18 Pharming B.V. Dna sequences to target proteins to the mammary gland for efficient secretion
US5633076A (en) 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5827690A (en) 1993-12-20 1998-10-27 Genzyme Transgenics Corporatiion Transgenic production of antibodies in milk
HUE033325T2 (en) * 2007-01-05 2017-11-28 Univ Zuerich Anti-beta-amyloid binder antibodies and their use
CN101883792B (zh) 2007-10-29 2014-08-27 基因创新有限公司 特异于β-淀粉状蛋白肽的新抗体以及其用作诊断剂或药物的用途
US8795664B2 (en) 2010-06-04 2014-08-05 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Monoclonal antibodies targeting amyloid beta oligomers
DK3269736T3 (da) * 2012-05-10 2020-01-13 Georg August Univ Goettingen Stiftung Oeffentlichen Rechts Univsmedizin Konformationsspecifikke antistoffer mod oligomerer af amyloid beta
WO2015173133A1 (en) 2014-05-12 2015-11-19 Chiesi Farmaceutici S.P.A. Formulations and methods of treating alzheimer's disease and other proteinopathies by combination therapy
NZ739181A (en) * 2015-07-16 2023-05-26 Vivoryon Therapeutics N V Anti-pyroglutamated amyloid beta humanized antibodies
CN111518206B (zh) * 2019-02-01 2022-03-29 长春金赛药业有限责任公司 人源化抗Aβ单克隆抗体及其应用
CN115698060A (zh) * 2020-03-10 2023-02-03 生命爱科 环肽

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