JP2022503427A5 - - Google Patents
Info
- Publication number
- JP2022503427A5 JP2022503427A5 JP2020572427A JP2020572427A JP2022503427A5 JP 2022503427 A5 JP2022503427 A5 JP 2022503427A5 JP 2020572427 A JP2020572427 A JP 2020572427A JP 2020572427 A JP2020572427 A JP 2020572427A JP 2022503427 A5 JP2022503427 A5 JP 2022503427A5
- Authority
- JP
- Japan
- Prior art keywords
- mutation
- amino acid
- functionally equivalent
- polymerase
- dna polymerase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862753558P | 2018-10-31 | 2018-10-31 | |
| US62/753,558 | 2018-10-31 | ||
| PCT/US2019/059246 WO2020092830A1 (en) | 2018-10-31 | 2019-10-31 | Polymerases, compositions, and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022503427A JP2022503427A (ja) | 2022-01-12 |
| JP2022503427A5 true JP2022503427A5 (https=) | 2022-07-04 |
| JP7515413B2 JP7515413B2 (ja) | 2024-07-12 |
Family
ID=68621372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572427A Active JP7515413B2 (ja) | 2018-10-31 | 2019-10-31 | ポリメラーゼ、組成物、および使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11104888B2 (https=) |
| EP (1) | EP3874036A1 (https=) |
| JP (1) | JP7515413B2 (https=) |
| KR (1) | KR102921926B1 (https=) |
| CN (1) | CN112673098B (https=) |
| AU (1) | AU2019374098B2 (https=) |
| BR (1) | BR112020026658A2 (https=) |
| CA (1) | CA3103719A1 (https=) |
| IL (2) | IL299237B2 (https=) |
| MX (1) | MX2020013347A (https=) |
| MY (1) | MY203805A (https=) |
| SG (1) | SG11202012493WA (https=) |
| WO (1) | WO2020092830A1 (https=) |
| ZA (1) | ZA202007838B (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3874036A1 (en) * | 2018-10-31 | 2021-09-08 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| WO2020117968A2 (en) | 2018-12-05 | 2020-06-11 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| US11293061B2 (en) | 2018-12-26 | 2022-04-05 | Illumina Cambridge Limited | Sequencing methods using nucleotides with 3′ AOM blocking group |
| JP2023510454A (ja) | 2019-11-27 | 2023-03-14 | イルミナ ケンブリッジ リミテッド | シクロオクタテトラエンを含有する色素及び組成物 |
| EP4081653B1 (en) | 2019-12-23 | 2024-07-03 | Singular Genomics Systems, Inc. | Methods for long read sequencing |
| AU2020416718A1 (en) | 2019-12-31 | 2022-07-07 | Singular Genomics Systems, Inc. | Polynucleotide barcodes for long read sequencing |
| US11174281B1 (en) | 2020-04-24 | 2021-11-16 | Singular Genomics Systems, Inc. | Modified nucleotides and uses thereof |
| US11787831B2 (en) | 2020-06-22 | 2023-10-17 | Illumina Cambridge Limited | Nucleosides and nucleotides with 3′ acetal blocking group |
| US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| US12054506B2 (en) | 2021-03-19 | 2024-08-06 | Singular Genomics Systems, Inc. | Reducing agents and uses thereof |
| MX2023011660A (es) * | 2021-03-31 | 2023-12-11 | Illumina Cambridge Ltd | Tecnicas de secuenciacion de genoteca de acido nucleico con deteccion de dimero adaptador. |
| JP2024516191A (ja) | 2021-05-05 | 2024-04-12 | イルミナ ケンブリッジ リミテッド | ビス－ホウ素縮合複素環を含有する蛍光色素及び配列決定における使用 |
| KR20240009435A (ko) | 2021-05-20 | 2024-01-22 | 일루미나, 인코포레이티드 | 합성에 의한 시퀀싱을 위한 조성물 및 방법 |
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| US12077789B2 (en) | 2021-08-14 | 2024-09-03 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| US11788075B2 (en) | 2022-02-18 | 2023-10-17 | Element Biosciences, Inc. | Engineered polymerases with reduced sequence-specific errors |
| US20230304086A1 (en) | 2022-03-28 | 2023-09-28 | Illumina Cambridge Limited | Labeled avidin and methods for sequencing |
| AU2023246772A1 (en) | 2022-03-29 | 2024-01-18 | Illumina Inc. | Chromenoquinoline dyes and uses in sequencing |
| CA3223037A1 (en) | 2022-03-30 | 2023-10-05 | Oliver MILLER | Methods for chemical cleavage of surface-bound polynucleotides |
| US20230357845A1 (en) | 2022-03-31 | 2023-11-09 | Illumina, Inc. | Compositions and methods for improving sequencing signals |
| WO2023192900A1 (en) | 2022-03-31 | 2023-10-05 | Illumina Singapore Pte. Ltd. | Nucleosides and nucleotides with 3' vinyl blocking group useful in sequencing by synthesis |
| CN119301275A (zh) | 2022-05-31 | 2025-01-10 | 伊路米纳有限公司 | 用于核酸测序的组合物和方法 |
| CN119604513A (zh) | 2022-06-28 | 2025-03-11 | 因美纳公司 | 含有稠合四环双硼杂环的荧光染料及其在测序中的用途 |
| US20240140939A1 (en) | 2022-09-30 | 2024-05-02 | Illumina Cambridge Limited | Compositions and methods for reducing photo damage during sequencing |
| US20240141427A1 (en) | 2022-09-30 | 2024-05-02 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| WO2024123866A1 (en) | 2022-12-09 | 2024-06-13 | Illumina, Inc. | Nucleosides and nucleotides with 3´ blocking groups and cleavable linkers |
| CN119095982A (zh) | 2022-12-22 | 2024-12-06 | 伊路米纳有限公司 | 用于边合成边测序的钯催化剂组合物和方法 |
| WO2024137765A1 (en) | 2022-12-22 | 2024-06-27 | Illumina, Inc. | Transition-metal catalyst compositions and methods for sequencing by synthesis |
| CN119095984A (zh) | 2022-12-27 | 2024-12-06 | 伊路米纳有限公司 | 使用3'烯丙基封端的核苷酸的测序方法 |
| CN118556118A (zh) * | 2023-01-04 | 2024-08-27 | 中元汇吉生物技术股份有限公司 | 一种dna聚合酶突变体、制备及其应用 |
| WO2024206407A2 (en) | 2023-03-29 | 2024-10-03 | Illumina, Inc. | Naphthalimide dyes and uses in nucleic acid sequencing |
| EP4689181A1 (en) | 2023-03-30 | 2026-02-11 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| EP4720334A1 (en) | 2023-05-26 | 2026-04-08 | Illumina, Inc. | Methods for preserving methylation status during clustering |
| WO2024249061A1 (en) | 2023-05-31 | 2024-12-05 | Illumina, Inc. | Detecting a methylated nucleotide using a quencher |
| CN121241132A (zh) * | 2023-06-02 | 2025-12-30 | 武汉华大智造科技有限公司 | 用于测序的dna聚合酶突变体 |
| WO2025049700A1 (en) | 2023-08-31 | 2025-03-06 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| WO2025090596A1 (en) | 2023-10-26 | 2025-05-01 | Illumina, Inc. | 4,5-substituted naphthalimide dyes and uses in nucleic acid sequencing |
| US20250163505A1 (en) | 2023-11-17 | 2025-05-22 | Illumina, Inc. | Conjugated polymers or polymer dots as fluorescent labels |
| US20250197933A1 (en) | 2023-12-18 | 2025-06-19 | Illumina, Inc. | Hydrogel nanoparticles as labeling scaffold in sequencing |
| WO2025144716A1 (en) | 2023-12-28 | 2025-07-03 | Illumina, Inc. | Nucleotides with enzymatically cleavable 3'-o-glycoside blocking groups for sequencing |
| US20250215494A1 (en) | 2023-12-29 | 2025-07-03 | Illumina, Inc. | Tricyclic polymethine dyes for nucleic acid sequencing |
| WO2025184226A1 (en) | 2024-02-28 | 2025-09-04 | Illumina, Inc. | Nucleotides with terminal phosphate capping |
| WO2025188906A1 (en) | 2024-03-08 | 2025-09-12 | Illumina, Inc. | Modified adenosine nucleotides |
| WO2025230914A1 (en) | 2024-04-29 | 2025-11-06 | Illumina, Inc. | Nucleotides with enzyme-triggered self-immolative linkers for sequencing by synthesis |
| WO2025264831A1 (en) | 2024-06-18 | 2025-12-26 | Illumina, Inc. | Methods for increasing sequencing quality of gc-rich regions |
| WO2025264836A1 (en) | 2024-06-18 | 2025-12-26 | Illumina, Inc. | Methods for increasing sequencing quality of gc-rich regions |
| WO2026006314A1 (en) | 2024-06-28 | 2026-01-02 | Illumina, Inc. | Tagging target regions prior to nucleotide sequencing |
| WO2026035914A1 (en) | 2024-08-09 | 2026-02-12 | Illumina, Inc. | Nucleotides having 3'-hydroxy blocking groups |
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| WO1997039150A1 (en) | 1996-04-15 | 1997-10-23 | University Of Southern California | Synthesis of fluorophore-labeled dna |
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| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
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-
2019
- 2019-10-31 EP EP19806368.7A patent/EP3874036A1/en active Pending
- 2019-10-31 SG SG11202012493WA patent/SG11202012493WA/en unknown
- 2019-10-31 MX MX2020013347A patent/MX2020013347A/es unknown
- 2019-10-31 US US16/670,876 patent/US11104888B2/en active Active
- 2019-10-31 KR KR1020207037274A patent/KR102921926B1/ko active Active
- 2019-10-31 AU AU2019374098A patent/AU2019374098B2/en active Active
- 2019-10-31 BR BR112020026658-2A patent/BR112020026658A2/pt not_active IP Right Cessation
- 2019-10-31 CN CN201980043453.3A patent/CN112673098B/zh active Active
- 2019-10-31 WO PCT/US2019/059246 patent/WO2020092830A1/en not_active Ceased
- 2019-10-31 JP JP2020572427A patent/JP7515413B2/ja active Active
- 2019-10-31 IL IL299237A patent/IL299237B2/en unknown
- 2019-10-31 MY MYPI2020006917A patent/MY203805A/en unknown
- 2019-10-31 CA CA3103719A patent/CA3103719A1/en active Pending
-
2020
- 2020-12-13 IL IL279422A patent/IL279422B2/en unknown
- 2020-12-15 ZA ZA2020/07838A patent/ZA202007838B/en unknown
-
2021
- 2021-08-09 US US17/397,003 patent/US11560552B2/en active Active
-
2022
- 2022-12-21 US US18/085,674 patent/US20230212534A1/en not_active Abandoned
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