JP2022119899A5 - - Google Patents
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- Publication number
- JP2022119899A5 JP2022119899A5 JP2022085941A JP2022085941A JP2022119899A5 JP 2022119899 A5 JP2022119899 A5 JP 2022119899A5 JP 2022085941 A JP2022085941 A JP 2022085941A JP 2022085941 A JP2022085941 A JP 2022085941A JP 2022119899 A5 JP2022119899 A5 JP 2022119899A5
- Authority
- JP
- Japan
- Prior art keywords
- pad2
- antibody
- antibody according
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101000735558 Homo sapiens Protein-arginine deiminase type-2 Proteins 0.000 claims 5
- 102100035735 Protein-arginine deiminase type-2 Human genes 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000027455 binding Effects 0.000 claims 1
- 230000006329 citrullination Effects 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018117142 | 2018-06-20 | ||
| JP2018117142 | 2018-06-20 | ||
| PCT/JP2019/024310 WO2019244934A1 (ja) | 2018-06-20 | 2019-06-19 | 新規抗ｐａｄ２抗体 |
| JP2020525771A JP7084057B2 (ja) | 2018-06-20 | 2019-06-19 | 新規抗ｐａｄ２抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020525771A Division JP7084057B2 (ja) | 2018-06-20 | 2019-06-19 | 新規抗ｐａｄ２抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022119899A JP2022119899A (ja) | 2022-08-17 |
| JP2022119899A5 true JP2022119899A5 (enExample) | 2022-10-13 |
| JP7411264B2 JP7411264B2 (ja) | 2024-01-11 |
Family
ID=68984058
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020525771A Active JP7084057B2 (ja) | 2018-06-20 | 2019-06-19 | 新規抗ｐａｄ２抗体 |
| JP2022085941A Active JP7411264B2 (ja) | 2018-06-20 | 2022-05-26 | 新規抗ｐａｄ２抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020525771A Active JP7084057B2 (ja) | 2018-06-20 | 2019-06-19 | 新規抗ｐａｄ２抗体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12559570B2 (enExample) |
| EP (1) | EP3816289A4 (enExample) |
| JP (2) | JP7084057B2 (enExample) |
| CN (1) | CN112262213A (enExample) |
| CA (1) | CA3102360A1 (enExample) |
| WO (1) | WO2019244934A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250236683A1 (en) | 2022-03-31 | 2025-07-24 | Pharma Foods International Co., Ltd. | Composition and method for inhibiting fibrosis |
| CN118001407B (zh) * | 2024-04-02 | 2024-06-21 | 北京大学人民医院 | Pad2在制备治疗缺血缺氧性恶性心律失常药物中的应用 |
| WO2026020127A2 (en) | 2024-07-19 | 2026-01-22 | Bristol-Myers Squibb Company | Methods of assessing citrullination and activity of pad2 modulators |
| CN121319198A (zh) * | 2025-04-14 | 2026-01-13 | 北京光辉天成生物科技有限公司 | 一种高亲和力padi2抗体及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US20040110938A1 (en) * | 2000-02-24 | 2004-06-10 | Parekh Rajesh Bhikhu | Proteins, genes and their use for diagnosis and treatment of schizophrenia |
| EP1729930A2 (en) * | 2004-04-01 | 2006-12-13 | Sequenom, Inc. | Methods for identifying risk of osteoarthritis and treatments thereof |
| WO2007095250A2 (en) * | 2006-02-13 | 2007-08-23 | The Cleveland Clinic Foundation | Compositions and methods for inhibiting optic nerve damage |
| CN101293924A (zh) | 2007-04-24 | 2008-10-29 | 上海国健生物技术研究院 | 骨桥蛋白的功能表位、与其特异性结合的单克隆抗体及其在制备抗肿瘤转移药物中的用途 |
| CN101293916A (zh) | 2007-04-24 | 2008-10-29 | 上海国健生物技术研究院 | 骨桥蛋白的功能表位、与其特异性结合的单克隆抗体及用途 |
| WO2009033743A1 (en) * | 2007-09-13 | 2009-03-19 | University Of Zurich Prorektorat Forschung | Monoclonal amyloid beta (abeta)-specific antibody and uses thereof |
| DK2294086T3 (en) * | 2008-06-04 | 2018-01-02 | Modiquest B V | ANTI-INFLAMMATORY AGENTS |
| US8975033B2 (en) * | 2012-11-05 | 2015-03-10 | The Johns Hopkins University | Human autoantibodies specific for PAD3 which are cross-reactive with PAD4 and their use in the diagnosis and treatment of rheumatoid arthritis and related diseases |
| US20150376294A1 (en) * | 2012-12-03 | 2015-12-31 | Rigshospitalet | Anti-pad2 antibodies and treatment of autoimmune diseases |
| CN104360070B (zh) * | 2014-11-28 | 2017-02-22 | 山东新创生物科技有限公司 | 肽基精氨酸脱亚胺酶2在制备肿瘤临床血液诊断试剂中的应用 |
| WO2016155745A1 (en) * | 2015-03-27 | 2016-10-06 | Rigshospitalet | Cross-reactive anti-pad antibodies |
| US20230203193A1 (en) | 2020-06-03 | 2023-06-29 | Georg F. Weber | Isolated antibodies and fragments thereof with specificity for osteopontin-c |
-
2019
- 2019-06-19 CN CN201980038636.6A patent/CN112262213A/zh active Pending
- 2019-06-19 WO PCT/JP2019/024310 patent/WO2019244934A1/ja not_active Ceased
- 2019-06-19 EP EP19823371.0A patent/EP3816289A4/en active Pending
- 2019-06-19 CA CA3102360A patent/CA3102360A1/en active Pending
- 2019-06-19 US US16/972,832 patent/US12559570B2/en active Active
- 2019-06-19 JP JP2020525771A patent/JP7084057B2/ja active Active
-
2022
- 2022-05-26 JP JP2022085941A patent/JP7411264B2/ja active Active
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