JP2019520550A5 - - Google Patents
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- Publication number
- JP2019520550A5 JP2019520550A5 JP2018555652A JP2018555652A JP2019520550A5 JP 2019520550 A5 JP2019520550 A5 JP 2019520550A5 JP 2018555652 A JP2018555652 A JP 2018555652A JP 2018555652 A JP2018555652 A JP 2018555652A JP 2019520550 A5 JP2019520550 A5 JP 2019520550A5
- Authority
- JP
- Japan
- Prior art keywords
- dpp3
- pharmaceutical composition
- inhibitor
- composition according
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022110620A JP2022163014A (ja) | 2016-04-21 | 2022-07-08 | Ｄｐｐ３の定量方法および治療方法 |
| JP2024178873A JP2025011237A (ja) | 2016-04-21 | 2024-10-11 | Ｄｐｐ３の定量方法および治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16166476 | 2016-04-21 | ||
| EP16166476.8 | 2016-04-21 | ||
| PCT/EP2017/059377 WO2017182561A1 (en) | 2016-04-21 | 2017-04-20 | Methods for determining dpp3 and therapeutic methods |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020076521A Division JP7219737B2 (ja) | 2016-04-21 | 2020-04-23 | Ｄｐｐ３の定量方法および治療方法 |
| JP2022110620A Division JP2022163014A (ja) | 2016-04-21 | 2022-07-08 | Ｄｐｐ３の定量方法および治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019520550A JP2019520550A (ja) | 2019-07-18 |
| JP2019520550A5 true JP2019520550A5 (enExample) | 2020-05-28 |
Family
ID=56014788
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555652A Pending JP2019520550A (ja) | 2016-04-21 | 2017-04-20 | Ｄｐｐ３の定量方法および治療方法 |
| JP2020076521A Active JP7219737B2 (ja) | 2016-04-21 | 2020-04-23 | Ｄｐｐ３の定量方法および治療方法 |
| JP2022110620A Pending JP2022163014A (ja) | 2016-04-21 | 2022-07-08 | Ｄｐｐ３の定量方法および治療方法 |
| JP2024178873A Pending JP2025011237A (ja) | 2016-04-21 | 2024-10-11 | Ｄｐｐ３の定量方法および治療方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020076521A Active JP7219737B2 (ja) | 2016-04-21 | 2020-04-23 | Ｄｐｐ３の定量方法および治療方法 |
| JP2022110620A Pending JP2022163014A (ja) | 2016-04-21 | 2022-07-08 | Ｄｐｐ３の定量方法および治療方法 |
| JP2024178873A Pending JP2025011237A (ja) | 2016-04-21 | 2024-10-11 | Ｄｐｐ３の定量方法および治療方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20190145981A1 (enExample) |
| EP (5) | EP3446125B1 (enExample) |
| JP (4) | JP2019520550A (enExample) |
| KR (3) | KR102886883B1 (enExample) |
| CN (3) | CN120992960A (enExample) |
| AU (2) | AU2017252212B2 (enExample) |
| BR (1) | BR112018071583A2 (enExample) |
| CA (2) | CA3021252A1 (enExample) |
| CH (1) | CH713803B1 (enExample) |
| DE (1) | DE112017002105T5 (enExample) |
| IL (1) | IL262472B2 (enExample) |
| MX (3) | MX2018012856A (enExample) |
| MY (1) | MY200300A (enExample) |
| SG (1) | SG11201809252YA (enExample) |
| WO (1) | WO2017182561A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL262472B2 (en) * | 2016-04-21 | 2024-12-01 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitors for use in treating diseases related to necrosis |
| KR102835427B1 (ko) * | 2017-10-25 | 2025-07-21 | 4틴4 파마슈티컬스 게엠베하 | 특이적 dpp3-에피토프에 대하여 지시되고 이에 결합하는 dpp3 결합제 및 산화적 스트레스와 연관되는 질환 / 급성 병태의 예방 또는 치료에서의 그의 용도 |
| US20220211798A1 (en) * | 2018-12-21 | 2022-07-07 | 4TEEN4 Pharmaceuticals GmbH | Therapy guidance and/or therapy monitoring for a treatment with angiotensin-receptor-agonist and/or a precursor thereof |
| WO2021038078A1 (en) * | 2019-08-30 | 2021-03-04 | 4TEEN4 Pharmaceuticals GmbH | Therapy guidance and/or therapy monitoring for treatment of shock |
| CA3168978A1 (en) * | 2020-02-27 | 2021-09-02 | Andreas Bergmann | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock |
| CN115244081A (zh) | 2020-02-27 | 2022-10-25 | 艾德里诺医药公司 | 用于治疗休克患者的抗肾上腺髓质素(adm)结合剂 |
| CN115244401A (zh) * | 2020-02-27 | 2022-10-25 | 4Teen4制药有限公司 | 用于在休克患者中进行nt-adm抗体的治疗指导、监测和分层的dpp3 |
| EP3922993A1 (en) * | 2020-06-12 | 2021-12-15 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| US20230213519A1 (en) * | 2020-03-16 | 2023-07-06 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| CN119072492A (zh) | 2022-03-15 | 2024-12-03 | 艾德里诺医药公司 | 抗肾上腺髓质素（adm）抗体或抗adm抗体片段的稳定水性制剂 |
| CN117186177B (zh) * | 2022-05-31 | 2024-08-23 | 中国农业大学 | 一种具有降尿酸活性的鸭血球蛋白肽及其制备方法 |
| US20260028423A1 (en) | 2022-07-29 | 2026-01-29 | 4TEEN4 Pharmaceuticals GmbH | Prediction of an increase of dpp3 in a patient with septic shock |
| IL318667A (en) | 2022-07-29 | 2025-03-01 | Adrenomed Ag | Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock |
| US20260201067A1 (en) | 2022-12-15 | 2026-07-16 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitor for improvement of pulmonary function in critically ill patients |
| CN115804836A (zh) * | 2022-12-27 | 2023-03-17 | 中国人民解放军海军特色医学中心 | 一种中枢小分子蛋白dpp3在制备降压药物中的应用 |
| JP2026513177A (ja) | 2023-03-29 | 2026-04-23 | ４ティーン４ ファーマシューティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血圧低下を有する重症患者における心筋保護及び心筋傷害の予防のためのｄｐｐ３阻害剤 |
| WO2026046968A1 (en) | 2024-08-26 | 2026-03-05 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 binders for the treatment of endothelial dysfunction |
| WO2026046947A1 (en) | 2024-08-26 | 2026-03-05 | 4TEEN4 Pharmaceuticals GmbH | Anti-dpp3 antibody directed to and binding to dpp3 for the treatment of shock in extreme-critically ill patients |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS6188884A (ja) | 1984-10-04 | 1986-05-07 | Sankyo Co Ltd | エンケフアリナ−ゼｂ阻害物質およびその製法 |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| JPH07503132A (ja) | 1991-12-17 | 1995-04-06 | ジェンファーム インターナショナル，インコーポレイティド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| JPH06219989A (ja) * | 1993-01-27 | 1994-08-09 | Microbial Chem Res Found | 新規生理活性物質フルオスタチンａおよびｂ、その製造法およびその用途 |
| GB9312324D0 (en) * | 1993-06-15 | 1993-07-28 | Pitman Moore Inc | Vaccine |
| US5612186A (en) | 1994-06-22 | 1997-03-18 | Food Industry Research And Development Institute | Enzyme-capture assay (ECA) for the identification of Escherichia coli in clinical samples |
| US5601986A (en) | 1994-07-14 | 1997-02-11 | Amgen Inc. | Assays and devices for the detection of extrahepatic biliary atresia |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| CA2383907A1 (en) | 1999-09-01 | 2001-03-08 | Incyte Genomics, Inc. | Human hydrolytic enzymes |
| AU2002225954A1 (en) * | 2000-11-08 | 2002-05-21 | The University Of Georgia Research Foundation, Inc. | Dipeptidylpeptidases and methods of use |
| CN1628126A (zh) | 2001-08-30 | 2005-06-15 | 比奥雷克西斯药物公司 | 经修饰的运铁蛋白融合蛋白 |
| PT2298278E (pt) | 2002-06-07 | 2016-02-25 | Dyax Corp | Prevenção e redução da perda de sangue e resposta inflamatória |
| CN1852974A (zh) * | 2003-06-09 | 2006-10-25 | 密歇根大学董事会 | 用于治疗和诊断癌症的组合物和方法 |
| CA2543360A1 (en) | 2003-10-24 | 2005-05-06 | Joost A. Kolkman | Ldl receptor class a and egf domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| WO2005106486A2 (en) | 2004-04-28 | 2005-11-10 | Bayer Healthcare Ag | Diagnostic and therapeutics for diseases associated with dipeptidyl-peptidase 3(dpp3) |
| CN1961077A (zh) * | 2004-06-01 | 2007-05-09 | 希森美康株式会社 | 酶活性测定方法及酶活性测定用柱 |
| AU2005287557B2 (en) | 2004-09-21 | 2011-10-13 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| JP2006230318A (ja) | 2005-02-25 | 2006-09-07 | Maruishi Pharmaceutical Co Ltd | 関節リウマチの診断方法 |
| CN100420947C (zh) * | 2005-05-30 | 2008-09-24 | 孙东旭 | 用单一捕获剂定量检测特异性分析物的方法及其试剂盒 |
| WO2007055979A2 (en) * | 2005-11-02 | 2007-05-18 | Meyer Pharmaceuticals Llc | Native trre: protein implicated in tnf receptor shedding for treating arthritis and inflammation |
| KR101376471B1 (ko) | 2006-03-13 | 2014-03-27 | 백톤 디킨슨 앤드 컴퍼니 | 디펩티딜 펩티다제-관련 질병 상태의 진단 및 예후 |
| CA2659082A1 (en) | 2006-06-07 | 2007-12-21 | Tethys Bioscience, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| ES2373832T3 (es) | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| NZ592591A (en) | 2008-11-03 | 2012-04-27 | Molecular Partners Ag | Binding proteins comprising ankyrin repeast domains that inhibit the vegf-a receptor interaction |
| WO2010093872A2 (en) * | 2009-02-13 | 2010-08-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Molecular-based method of cancer diagnosis and prognosis |
| CA2772162C (en) | 2009-08-27 | 2018-05-22 | Covagen Ag | Anti-il-17a fynomers and medical uses thereof |
| BR112012014417B1 (pt) | 2009-12-14 | 2021-11-09 | Scil Proteins Gmbh | Proteínas ubiquitinas modificadas tendo uma atividade de ligação específica para o extradomínio b de fibronectina |
| KR101234352B1 (ko) * | 2010-03-18 | 2013-02-15 | 권동락 | 선택적 면역 세포 분리 반출장치 |
| AU2011263786B2 (en) | 2010-06-08 | 2014-11-13 | Astrazeneca Ab | Tear lipocalin muteins binding IL-4 R alpha |
| CN104946646B (zh) * | 2014-03-25 | 2020-03-31 | 中国医学科学院基础医学研究所 | 用于预防和/或治疗埃博拉病毒性出血热的小核酸分子、dna分子、蛋白及应用 |
| IL262472B2 (en) * | 2016-04-21 | 2024-12-01 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitors for use in treating diseases related to necrosis |
-
2017
- 2017-04-20 IL IL262472A patent/IL262472B2/en unknown
- 2017-04-20 CA CA3021252A patent/CA3021252A1/en active Pending
- 2017-04-20 JP JP2018555652A patent/JP2019520550A/ja active Pending
- 2017-04-20 EP EP17720047.4A patent/EP3446125B1/en active Active
- 2017-04-20 EP EP21153560.4A patent/EP3896450A1/en active Pending
- 2017-04-20 MY MYPI2018703855A patent/MY200300A/en unknown
- 2017-04-20 KR KR1020237026743A patent/KR102886883B1/ko active Active
- 2017-04-20 KR KR1020247025458A patent/KR102886863B1/ko active Active
- 2017-04-20 CH CH001280/2018A patent/CH713803B1/de unknown
- 2017-04-20 CN CN202511191873.XA patent/CN120992960A/zh active Pending
- 2017-04-20 WO PCT/EP2017/059377 patent/WO2017182561A1/en not_active Ceased
- 2017-04-20 BR BR112018071583-2A patent/BR112018071583A2/pt unknown
- 2017-04-20 CA CA3264486A patent/CA3264486A1/en active Pending
- 2017-04-20 CN CN201780039077.1A patent/CN110168372A/zh active Pending
- 2017-04-20 EP EP21153574.5A patent/EP3854817A1/en active Pending
- 2017-04-20 CN CN202510254123.6A patent/CN120093910A/zh active Pending
- 2017-04-20 EP EP24178565.8A patent/EP4417217A3/en active Pending
- 2017-04-20 KR KR1020187033194A patent/KR102565453B1/ko active Active
- 2017-04-20 US US16/095,563 patent/US20190145981A1/en active Pending
- 2017-04-20 SG SG11201809252YA patent/SG11201809252YA/en unknown
- 2017-04-20 AU AU2017252212A patent/AU2017252212B2/en active Active
- 2017-04-20 EP EP24178574.0A patent/EP4417218A3/en active Pending
- 2017-04-20 MX MX2018012856A patent/MX2018012856A/es unknown
- 2017-04-20 DE DE112017002105.7T patent/DE112017002105T5/de active Pending
-
2018
- 2018-10-19 MX MX2025006655A patent/MX2025006655A/es unknown
- 2018-10-19 MX MX2020001193A patent/MX2020001193A/es unknown
-
2020
- 2020-04-23 JP JP2020076521A patent/JP7219737B2/ja active Active
- 2020-07-02 US US16/919,449 patent/US11726094B2/en active Active
-
2022
- 2022-07-08 JP JP2022110620A patent/JP2022163014A/ja active Pending
-
2023
- 2023-06-21 US US18/338,805 patent/US20240385197A1/en active Pending
- 2023-11-02 AU AU2023258417A patent/AU2023258417B2/en active Active
-
2024
- 2024-10-11 JP JP2024178873A patent/JP2025011237A/ja active Pending
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