JP2011522561A5 - - Google Patents
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- Publication number
- JP2011522561A5 JP2011522561A5 JP2011513436A JP2011513436A JP2011522561A5 JP 2011522561 A5 JP2011522561 A5 JP 2011522561A5 JP 2011513436 A JP2011513436 A JP 2011513436A JP 2011513436 A JP2011513436 A JP 2011513436A JP 2011522561 A5 JP2011522561 A5 JP 2011522561A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic peptide
- recombinant phage
- peptide according
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 26
- 241000712461 unidentified influenza virus Species 0.000 claims description 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 11
- 230000004927 fusion Effects 0.000 claims description 10
- 241000700605 Viruses Species 0.000 claims description 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 5
- 102000012750 Membrane Glycoproteins Human genes 0.000 claims description 3
- 108010090054 Membrane Glycoproteins Proteins 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 208000002979 Influenza in Birds Diseases 0.000 claims 2
- 206010064097 avian influenza Diseases 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 210000002845 virion Anatomy 0.000 description 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 2
- 102000018697 Membrane Proteins Human genes 0.000 description 2
- 108010052285 Membrane Proteins Proteins 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 229940098773 bovine serum albumin Drugs 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 101710132601 Capsid protein Proteins 0.000 description 1
- 101710094648 Coat protein Proteins 0.000 description 1
- 108091035707 Consensus sequence Proteins 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- 101710125418 Major capsid protein Proteins 0.000 description 1
- 101710141454 Nucleoprotein Proteins 0.000 description 1
- 101710083689 Probable capsid protein Proteins 0.000 description 1
- 108010090804 Streptavidin Proteins 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 229940039227 diagnostic agent Drugs 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 238000004091 panning Methods 0.000 description 1
- 238000002823 phage display Methods 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000017610 release of virus from host Effects 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 230000007502 viral entry Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI20082061A MY160435A (en) | 2008-06-12 | 2008-06-12 | A novel antiviral peptide against avian influenza virus h9n2 |
| MYPI20082061 | 2008-06-12 | ||
| PCT/MY2009/000071 WO2009151313A1 (en) | 2008-06-12 | 2009-06-10 | A novel antiviral peptide against avian influenza virus h9n2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011522561A JP2011522561A (ja) | 2011-08-04 |
| JP2011522561A5 true JP2011522561A5 (enExample) | 2012-07-19 |
| JP5647111B2 JP5647111B2 (ja) | 2014-12-24 |
Family
ID=41416902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011513436A Expired - Fee Related JP5647111B2 (ja) | 2008-06-12 | 2009-06-10 | トリインフルエンザウイルスｈ９ｎ２に対する新規な抗ウイルスペプチド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8883480B2 (enExample) |
| EP (1) | EP2300492B1 (enExample) |
| JP (1) | JP5647111B2 (enExample) |
| DK (1) | DK2300492T3 (enExample) |
| MY (1) | MY160435A (enExample) |
| WO (1) | WO2009151313A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013540425A (ja) * | 2010-08-03 | 2013-11-07 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーション | インフルエンザ感染の治療および制限のうち少なくとも一方を行うためのポリペプチド |
| CN102830225B (zh) * | 2012-09-24 | 2014-06-04 | 中国动物疫病预防控制中心 | 一种源于禽流感病毒自然弱毒株的血凝素和免疫抗原 |
| MY184269A (en) * | 2015-11-27 | 2021-03-30 | Viramatix Sdn Bhd | Broad-spectrum anti-influenza virus therapeutic peptides |
| KR20200012894A (ko) | 2017-05-26 | 2020-02-05 | 비라매틱스 에스디엔 비에이치디 | 펩타이드 및 항바이러스제로서의 이의 용도 |
| WO2020006494A1 (en) | 2018-06-29 | 2020-01-02 | Fred Hutchinson Cancer Research Center | Cell-stored barcoded deep mutational scanning libraries and uses of the same |
| CN109487011B (zh) * | 2019-01-07 | 2022-03-01 | 广西壮族自治区兽医研究所 | 用于检测h5、h7和h9以及9个na亚型aiv的引物组合及其应用 |
| CN109487012B (zh) * | 2019-01-07 | 2020-09-22 | 广西壮族自治区兽医研究所 | 用于检测9个na亚型aiv的引物组合及其应用 |
| CN109628641B (zh) * | 2019-01-07 | 2022-03-01 | 广西壮族自治区兽医研究所 | 用于检测h7以及5个na亚型aiv的引物组合及其应用 |
| US11821111B2 (en) | 2019-11-15 | 2023-11-21 | Fred Hutchinson Cancer Center | Barcoded influenza viruses and deep mutational scanning libraries including the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| NZ506987A (en) * | 1998-03-17 | 2003-01-31 | Sangamo Biosciences Inc | Nucleic acid binding proteins |
| WO2000059932A1 (fr) * | 1999-03-31 | 2000-10-12 | Otsuka Pharmaceutical Co., Ltd. | Peptides se liant a l'hemagglutinine du virus de la grippe |
| WO2003006620A2 (en) * | 2001-07-11 | 2003-01-23 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptides |
| US7888121B2 (en) * | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| WO2007022425A2 (en) * | 2005-08-16 | 2007-02-22 | Hawaii Biotech, Inc. | Influenza recombinant subunit vaccine |
| JP5093100B2 (ja) * | 2006-03-13 | 2012-12-05 | 学校法人慶應義塾 | インフルエンザ感染阻害ペプチド、インフルエンザウイルス感染阻害剤、リポソーム、インフルエンザ予防・治療剤 |
| KR20090031938A (ko) * | 2006-07-05 | 2009-03-30 | 더 스크립스 리서치 인스티튜트 | 방향성 진화로 촉매 작용을 최적화시킨 키메라 징크 핑거 리컴비나제 |
| US8778847B2 (en) * | 2007-06-13 | 2014-07-15 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic peptides of influenza virus |
| EP2174957B1 (en) * | 2007-06-15 | 2016-03-16 | Xiamen University | Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof |
-
2008
- 2008-06-12 MY MYPI20082061A patent/MY160435A/en unknown
-
2009
- 2009-06-10 US US12/995,889 patent/US8883480B2/en not_active Expired - Fee Related
- 2009-06-10 EP EP09762696.4A patent/EP2300492B1/en not_active Not-in-force
- 2009-06-10 JP JP2011513436A patent/JP5647111B2/ja not_active Expired - Fee Related
- 2009-06-10 DK DK09762696.4T patent/DK2300492T3/da active
- 2009-06-10 WO PCT/MY2009/000071 patent/WO2009151313A1/en not_active Ceased
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