JP2021535213A5 - - Google Patents
Info
- Publication number
- JP2021535213A5 JP2021535213A5 JP2021534826A JP2021534826A JP2021535213A5 JP 2021535213 A5 JP2021535213 A5 JP 2021535213A5 JP 2021534826 A JP2021534826 A JP 2021534826A JP 2021534826 A JP2021534826 A JP 2021534826A JP 2021535213 A5 JP2021535213 A5 JP 2021535213A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- compound
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201807244X | 2018-08-24 | ||
| SG10201807244X | 2018-08-24 | ||
| PCT/EP2019/072641 WO2020039093A1 (en) | 2018-08-24 | 2019-08-23 | Tetrahydropyridopyrimidine derivatives as ahr modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021535213A JP2021535213A (ja) | 2021-12-16 |
| JP2021535213A5 true JP2021535213A5 (https=) | 2022-08-30 |
Family
ID=67982013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534826A Pending JP2021535213A (ja) | 2018-08-24 | 2019-08-23 | ＡｈＲモジュレーターとしてのテトラヒドロピリドピリミジン誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12221439B2 (https=) |
| EP (1) | EP3841102B1 (https=) |
| JP (1) | JP2021535213A (https=) |
| KR (1) | KR20210049135A (https=) |
| CN (1) | CN112739698A (https=) |
| AU (1) | AU2019323714A1 (https=) |
| BR (1) | BR112021003529A2 (https=) |
| CA (1) | CA3110402A1 (https=) |
| IL (1) | IL281023A (https=) |
| MX (1) | MX2021002215A (https=) |
| PH (1) | PH12021550382A1 (https=) |
| SG (1) | SG11202101441SA (https=) |
| WO (1) | WO2020039093A1 (https=) |
| ZA (1) | ZA202100931B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3715471A1 (en) | 2019-03-29 | 2020-09-30 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Ahr signature marker set |
| EP3721894A1 (en) | 2019-04-10 | 2020-10-14 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Interleukin-4-induced gene 1 (il4i1) as a biomarker and uses thereof |
| EP3835432A1 (en) | 2019-12-10 | 2021-06-16 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Interleukin-4-induced gene 1 (il4i1) and respective metabolites as biomarkers for cancer |
| JP2023515128A (ja) | 2020-02-26 | 2023-04-12 | ジャガー セラピューティクス ピーティーイーリミテッド | Ａｈｒシグナル伝達の調節に有用なピリドピリミジン誘導体 |
| BR112022020965A2 (pt) * | 2020-04-17 | 2022-12-06 | Dong A St Co Ltd | Derivados de piridopirimidinona e seu uso como moduladores de receptores de hidrocarboneto arila |
| CN114369097B (zh) * | 2020-10-15 | 2023-07-14 | 山东轩竹医药科技有限公司 | 杂芳环类AhR抑制剂 |
| WO2023033741A1 (en) * | 2021-09-02 | 2023-03-09 | Jaguahr Therapeutics Pte Ltd | Compounds useful in modulation of ahr signalling |
| WO2023033742A1 (en) * | 2021-09-02 | 2023-03-09 | Jaguahr Therapeutics Pte Ltd | Compounds useful in modulation of ahr signalling |
| CN119948035A (zh) | 2022-10-03 | 2025-05-06 | 捷豹治疗有限公司 | 可用于调节AhR信号传导的化合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| WO2002022605A1 (en) | 2000-09-15 | 2002-03-21 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| CN1894222A (zh) * | 2003-08-05 | 2007-01-10 | 沃泰克斯药物股份有限公司 | 作为电压门控离子通道抑制剂的稠合嘧啶化合物 |
| WO2006044762A2 (en) * | 2004-10-15 | 2006-04-27 | Bayer Pharmaceuticals Corporation | Tetrahydro-5h-pyrimido[4,5-d]azepine derivatives useful for the treatment of diseases associated with the 5-ht2c receptor |
| JP2012504591A (ja) | 2008-10-02 | 2012-02-23 | レスピバート・リミテツド | ｐ３８ＭＡＰキナーゼ阻害剤 |
| PE20100362A1 (es) * | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| EP2467382B1 (en) * | 2009-08-17 | 2014-06-25 | Merck Sharp & Dohme Corp. | Amino tetrahydro-pyridopyrimidine pde10 inhibitors |
| AU2011282776B2 (en) | 2010-07-27 | 2014-06-12 | Boston Medical Center Corporation | Aryl hydrocarbon receptor (AhR) modifiers as novel cancer therapeutics |
| WO2016154110A1 (en) * | 2015-03-20 | 2016-09-29 | Cleave Biosciences, Inc. | Companion diagnostic for p97 inhibitor therapy and methods of use thereof |
| AU2017269870A1 (en) | 2016-05-25 | 2018-12-06 | Bayer Pharma Aktiengesellschaft | 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides |
| JP2023515128A (ja) | 2020-02-26 | 2023-04-12 | ジャガー セラピューティクス ピーティーイーリミテッド | Ａｈｒシグナル伝達の調節に有用なピリドピリミジン誘導体 |
-
2019
- 2019-08-23 WO PCT/EP2019/072641 patent/WO2020039093A1/en not_active Ceased
- 2019-08-23 AU AU2019323714A patent/AU2019323714A1/en not_active Abandoned
- 2019-08-23 EP EP19769387.2A patent/EP3841102B1/en active Active
- 2019-08-23 US US17/270,626 patent/US12221439B2/en active Active
- 2019-08-23 BR BR112021003529-0A patent/BR112021003529A2/pt not_active Application Discontinuation
- 2019-08-23 MX MX2021002215A patent/MX2021002215A/es unknown
- 2019-08-23 SG SG11202101441SA patent/SG11202101441SA/en unknown
- 2019-08-23 KR KR1020217008532A patent/KR20210049135A/ko not_active Ceased
- 2019-08-23 CN CN201980060477.XA patent/CN112739698A/zh active Pending
- 2019-08-23 JP JP2021534826A patent/JP2021535213A/ja active Pending
- 2019-08-23 CA CA3110402A patent/CA3110402A1/en active Pending
-
2021
- 2021-02-10 ZA ZA2021/00931A patent/ZA202100931B/en unknown
- 2021-02-22 IL IL281023A patent/IL281023A/en unknown
- 2021-02-24 PH PH12021550382A patent/PH12021550382A1/en unknown
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