JP2021534740A5 - - Google Patents

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Publication number
JP2021534740A5
JP2021534740A5 JP2021507503A JP2021507503A JP2021534740A5 JP 2021534740 A5 JP2021534740 A5 JP 2021534740A5 JP 2021507503 A JP2021507503 A JP 2021507503A JP 2021507503 A JP2021507503 A JP 2021507503A JP 2021534740 A5 JP2021534740 A5 JP 2021534740A5
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JP
Japan
Prior art keywords
genetically modified
modified hematopoietic
nucleic acid
nucleotide sequence
domain
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021507503A
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English (en)
Japanese (ja)
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JP7456638B2 (ja
JP2021534740A (ja
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Priority claimed from PCT/US2019/046550 external-priority patent/WO2020037066A1/en
Publication of JP2021534740A publication Critical patent/JP2021534740A/ja
Publication of JP2021534740A5 publication Critical patent/JP2021534740A5/ja
Application granted granted Critical
Publication of JP7456638B2 publication Critical patent/JP7456638B2/ja
Active legal-status Critical Current
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JP2021507503A 2018-08-14 2019-08-14 クレブス回路を調節するトランス代謝分子と組み合わせたキメラ抗原受容体ポリペプチド、及び、それらの治療的使用 Active JP7456638B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862718491P 2018-08-14 2018-08-14
US201862718579P 2018-08-14 2018-08-14
US62/718,579 2018-08-14
US62/718,491 2018-08-14
PCT/US2019/046550 WO2020037066A1 (en) 2018-08-14 2019-08-14 Chimeric antigen receptor polypeptides in combination with trans metabolism molecules modulating krebs cycle and therapeutic uses thereof

Publications (3)

Publication Number Publication Date
JP2021534740A JP2021534740A (ja) 2021-12-16
JP2021534740A5 true JP2021534740A5 (enExample) 2022-08-22
JP7456638B2 JP7456638B2 (ja) 2024-03-27

Family

ID=69524868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021507503A Active JP7456638B2 (ja) 2018-08-14 2019-08-14 クレブス回路を調節するトランス代謝分子と組み合わせたキメラ抗原受容体ポリペプチド、及び、それらの治療的使用

Country Status (13)

Country Link
US (2) US12077785B2 (enExample)
EP (1) EP3837353A4 (enExample)
JP (1) JP7456638B2 (enExample)
KR (1) KR20210045418A (enExample)
CN (1) CN112840019B (enExample)
AU (1) AU2019321540B2 (enExample)
BR (1) BR112021001694A2 (enExample)
CA (1) CA3108126A1 (enExample)
IL (1) IL280322B2 (enExample)
MX (1) MX2021001771A (enExample)
SG (1) SG11202101284UA (enExample)
WO (1) WO2020037066A1 (enExample)
ZA (1) ZA202100993B (enExample)

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JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を治療するための方法
WO2023049933A1 (en) 2021-09-27 2023-03-30 Sotio Biotech Inc. Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof
AU2022388928A1 (en) 2021-11-16 2024-05-16 Sotio Biotech Inc. Treatment of myxoid/round cell liposarcoma patients
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WO2024040207A1 (en) 2022-08-19 2024-02-22 Sotio Biotech Inc. Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
WO2024040208A1 (en) 2022-08-19 2024-02-22 Sotio Biotech Inc. Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
EP4694916A1 (en) 2023-04-14 2026-02-18 SOTIO Biotech Inc. Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
WO2024215987A1 (en) 2023-04-14 2024-10-17 Sotio Biotech Inc. IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
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