|
FR2358891A1
(fr)
|
1976-07-22 |
1978-02-17 |
Yamanouchi Pharma Co Ltd |
Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires
|
|
FR2549834B1
(fr)
|
1983-07-25 |
1985-10-18 |
Sanofi Sa |
Derives de triazolo-pyrimidine, leur procede de preparation et leur application therapeutique en tant que tonicardiaques
|
|
US4921854A
(en)
|
1986-12-30 |
1990-05-01 |
Egis Gyogyszergyar |
Condensed thiazolopyrimidine, pyrimido-thiazine or thiazepine pyrimidine compounds
|
|
US5298502A
(en)
|
1988-12-12 |
1994-03-29 |
Fmc Corporation |
Method and composition for photodynamic treatment and detection of tumors
|
|
AU6643694A
(en)
|
1993-05-21 |
1994-12-20 |
Pentapharm Ag |
3-(mercaptoalkyl)- or 3-(alkylthioalkyl)- pyrimidin-2,4(1h, 3h)-diones
|
|
JP2000513375A
(ja)
|
1996-06-28 |
2000-10-10 |
メルク エンド カンパニー インコーポレーテッド |
フィブリノーゲンレセプター拮抗薬プロドラッグ
|
|
US6339093B1
(en)
|
1999-10-08 |
2002-01-15 |
Hoffmann-La Roche Inc. |
Isoquinoline derivatives
|
|
EP1296958A4
(en)
|
2000-06-26 |
2004-01-28 |
Merck & Co Inc |
ANTIAGONISTS OF NMDA NR2B RECEPTORS OF IMINOPYRIMIDINE
|
|
WO2003024955A2
(en)
|
2001-09-18 |
2003-03-27 |
Sunesis Pharmaceuticals, Inc. |
Small molecule inhibitors of caspases
|
|
AR038118A1
(es)
|
2002-01-14 |
2004-12-29 |
Upjohn Co |
Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
|
|
US7005432B2
(en)
|
2002-05-16 |
2006-02-28 |
Hoffman-La Roche Inc. |
Substituted imidazol-pyridazine derivatives
|
|
EP1768960A1
(en)
|
2004-07-13 |
2007-04-04 |
F.Hoffmann-La Roche Ag |
Sulfonamide derivatives
|
|
TW200643015A
(en)
|
2005-03-11 |
2006-12-16 |
Akzo Nobel Nv |
2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
|
|
AR056155A1
(es)
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
|
EP2066640B1
(en)
|
2006-09-11 |
2011-09-07 |
N.V. Organon |
2-(1-oxo-1h-isoquinolin-2-yl) acetamide derivatives
|
|
CN101600698B
(zh)
|
2006-09-11 |
2012-01-11 |
欧加农股份有限公司;药典有限责任公司 |
喹唑啉酮和异喹啉酮乙酰胺衍生物
|
|
WO2008076883A2
(en)
|
2006-12-15 |
2008-06-26 |
Abraxis Bioscience, Inc. |
Triazine derivatives and their therapeutical applications
|
|
EP1939187A1
(en)
|
2006-12-20 |
2008-07-02 |
Sanofi-Aventis |
Substituted heteroaryl pyridopyrimidone derivatives
|
|
JP2010518080A
(ja)
|
2007-02-08 |
2010-05-27 |
メルク・シャープ・エンド・ドーム・コーポレイション |
治療薬
|
|
DK2160389T3
(da)
|
2007-04-18 |
2014-06-23 |
Probiodrug Ag |
Thioxoquinazolinonderivater som glutaminylcyclaseinhibitorer
|
|
CA2685753A1
(en)
|
2007-05-09 |
2008-11-20 |
Neuromed Pharmaceuticals Ltd. |
Bicyclic pyrimidine derivatives as calcium channel blockers
|
|
US8653059B2
(en)
|
2007-08-21 |
2014-02-18 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
TW200934497A
(en)
|
2007-11-13 |
2009-08-16 |
Organon Nv |
Heterocyclic derivatives
|
|
ES2586459T3
(es)
|
2008-05-01 |
2016-10-14 |
Glaxosmithkline Llc |
Quinolinas y análogos relacionados como moduladores de sirtuina
|
|
WO2009146358A1
(en)
|
2008-05-29 |
2009-12-03 |
Sirtris Pharmaceuticals, Inc. |
Imidazopyridine and related analogs as sirtuin modulators
|
|
EP2138494A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted alkyl pyrimidin-4-one derivatives
|
|
CA2729128C
(en)
|
2008-07-03 |
2016-05-31 |
Sirtris Pharmaceuticals, Inc. |
Benzimidazoles and related analogs as sirtuin modulators
|
|
CN101628913B
(zh)
|
2008-07-18 |
2013-01-23 |
中国科学院广州生物医药与健康研究院 |
用作雌激素相关受体调节剂的化合物及其应用
|
|
MX2011003373A
(es)
|
2008-09-29 |
2011-06-09 |
Sirtris Pharmaceuticals Inc |
Quinazolinona, quinolona y analogos relacionados como moduladores de sirtuina.
|
|
PE20120008A1
(es)
|
2009-01-12 |
2012-01-24 |
Icagen Inc |
Derivados de fenoxi bencenosulfonamida
|
|
WO2010111573A1
(en)
|
2009-03-27 |
2010-09-30 |
Abbott Laboratories |
Compounds as cannabinoid receptor ligands
|
|
EP2264035A1
(en)
|
2009-06-04 |
2010-12-22 |
Merz Pharma GmbH & Co. KGaA |
Glycine B antagonists
|
|
TW201116532A
(en)
|
2009-08-05 |
2011-05-16 |
Merz Pharma Gmbh & Co Kgaa |
Metabotropic glutamate receptor modulators
|
|
US8841289B2
(en)
|
2009-10-13 |
2014-09-23 |
Merck Sharp & Dohme B.V. |
Heterocyclic derivatives
|
|
WO2011117382A1
(en)
|
2010-03-26 |
2011-09-29 |
Boehringer Ingelheim International Gmbh |
Pyridyltriazoles
|
|
WO2011117381A1
(en)
|
2010-03-26 |
2011-09-29 |
Boehringer Ingelheim International Gmbh |
B-raf kinase inhibitors
|
|
CA2805724A1
(en)
|
2010-07-16 |
2012-01-19 |
Rockefeller University |
Oxadiazolo[3,2-a]pyrimidines and thiadiazolo[3,2-a]pyrimidines
|
|
US9394290B2
(en)
|
2010-10-21 |
2016-07-19 |
Universitaet Des Saarlandes Campus Saarbruecken |
Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
|
|
US20120165330A1
(en)
|
2010-12-22 |
2012-06-28 |
Sirtris Pharmaceuticals, Inc. |
Quinazolinone and related analogs as sirtuin modulators
|
|
US9464065B2
(en)
|
2011-03-24 |
2016-10-11 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
KR20140033377A
(ko)
|
2011-05-10 |
2014-03-18 |
길리애드 사이언시즈, 인코포레이티드 |
나트륨 채널 조절제로서의 융합된 헤테로시클릭 화합물
|
|
US9493412B2
(en)
|
2011-09-27 |
2016-11-15 |
Bristol-Myers Squibb Company |
Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
|
|
WO2013049104A1
(en)
|
2011-09-30 |
2013-04-04 |
Bristol-Myers Squibb Company |
Pyridinedione carboxamide inhibitors of endothelial lipase
|
|
EP2760840B1
(en)
|
2011-09-30 |
2015-08-12 |
Bristol-Myers Squibb Company |
Quinolinone carboxamide inhibitors of endothelial lipase
|
|
CN102336768A
(zh)
|
2011-10-24 |
2012-02-01 |
中国科学院上海有机化学研究所 |
N’-芳亚甲基-2-(4-氧代噻吩[2,3-d]嘧啶-3-基)乙酰腙类化合物、制备方法和用途
|
|
RS57157B1
(sr)
|
2011-11-11 |
2018-07-31 |
Gilead Apollo Llc |
Acc inhibitori i njihove primene
|
|
DK2812004T3
(en)
|
2012-02-10 |
2018-10-15 |
Ptc Therapeutics Inc |
COMPOUNDS FOR TREATMENT OF SPINAL MUSCLE DROPHY
|
|
WO2014066743A1
(en)
|
2012-10-25 |
2014-05-01 |
Bioenergenix |
Heterocyclic compounds for the inhibition of pask
|
|
WO2014139144A1
(en)
|
2013-03-15 |
2014-09-18 |
Agios Pharmaceuticals, Inc. |
Therapeutic compounds and compositions
|
|
WO2014179144A1
(en)
|
2013-04-29 |
2014-11-06 |
E. I. Du Pont De Nemours And Company |
Fungicidal heterocyclic compounds
|
|
EA029412B1
(ru)
|
2013-06-28 |
2018-03-30 |
Бейджин, Лтд. |
Конденсированные трициклические соединения мочевины в качестве ингибиторов киназы raf и/или димера киназы raf
|
|
WO2015007453A1
(en)
|
2013-07-15 |
2015-01-22 |
Syngenta Participations Ag |
Microbiocidal heterobicyclic derivatives
|
|
WO2015048503A2
(en)
|
2013-09-26 |
2015-04-02 |
Mnemosyne Pharmaceuticals, Inc. |
N-arylmethyl sulfonamide negative modulators of nr2a
|
|
LT3055315T
(lt)
|
2013-10-11 |
2018-10-25 |
F. Hoffmann-La Roche Ag |
Tiazolpirimidinonai kaip nmda receptorių aktyvumo moduliatoriai
|
|
WO2015064714A1
(ja)
|
2013-10-31 |
2015-05-07 |
国立大学法人東京大学 |
オートタキシン阻害活性を有する１－置換イミダゾピリミジノン誘導体
|
|
CN103664877A
(zh)
|
2013-12-25 |
2014-03-26 |
重庆医药工业研究院有限责任公司 |
一种喹啉衍生物、其制备方法和应用
|
|
US9617226B2
(en)
|
2014-09-05 |
2017-04-11 |
AbbVie Deutschland GmbH & Co. KG |
Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases
|
|
US12006328B2
(en)
|
2014-11-18 |
2024-06-11 |
Emory University |
Thieno[2,3-d]pyrimidin-4-one derivatives as NMDAR modulators and uses related thereto
|
|
RU2717665C2
(ru)
|
2015-04-15 |
2020-03-24 |
Ф. Хоффманн-Ля Рош Аг |
Пиридопиримидиноны и их применение в качестве модуляторов рецептора n-метил-d-аспартата
|
|
CN108601814A
(zh)
|
2015-10-16 |
2018-09-28 |
西北大学 |
用于治疗精神分裂症、双相障碍、认知损害和重度抑郁障碍的非典型抗精神病药和nmda调节剂的药物组合
|
|
EP4006038A1
(en)
|
2015-12-09 |
2022-06-01 |
Cadent Therapeutics, Inc. |
Thienopyrimidinone nmda receptor modulators and uses thereof
|
|
JP7071917B2
(ja)
|
2015-12-09 |
2022-05-19 |
カデント セラピューティクス，インコーポレーテッド |
ヘテロ芳香族ｎｍｄａ受容体モジュレーターおよびその使用
|
|
US20170305861A1
(en)
|
2016-04-25 |
2017-10-26 |
Immunomet Therapeutics, Inc |
Heteroaryl compounds comprising nitrogen and use thereof
|
|
US11186564B2
(en)
|
2016-08-04 |
2021-11-30 |
Sunovion Pharmaceuticals Inc. |
Dual NAV1.2/5HT2a inhibitors for treating CNS disorders
|
|
US11274107B2
(en)
|
2016-12-22 |
2022-03-15 |
Cadent Therapeutics, Inc. |
NMDA receptor modulators and uses thereof
|
|
MA50655B1
(fr)
|
2017-09-27 |
2021-11-30 |
Incyte Corp |
Sels de dérivés de pyrrolotriazine utiles en tant qu'inhibiteurs de tam
|
|
AR115905A1
(es)
|
2018-08-03 |
2021-03-10 |
Cadent Therapeutics Inc |
5-(3-cloro-4-fluorofenil)-7-ciclopropil-3-(2-(3-fluoro-3-metilazetidin-1-il)-2-oxoetil)-3,7-dihidro-4h-pirrolo[2,3-d]pirimidin-4-ona como modulador de los receptores de nmda
|
|
US11554120B2
(en)
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|