EP3406252B1 - Compounds for treating spinal muscular atrophy - Google Patents

Compounds for treating spinal muscular atrophy Download PDF

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Publication number
EP3406252B1
EP3406252B1 EP18179491.8A EP18179491A EP3406252B1 EP 3406252 B1 EP3406252 B1 EP 3406252B1 EP 18179491 A EP18179491 A EP 18179491A EP 3406252 B1 EP3406252 B1 EP 3406252B1
Authority
EP
European Patent Office
Prior art keywords
alkyl
pyrimidin
pyrido
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP18179491.8A
Other languages
German (de)
French (fr)
Other versions
EP3406252A1 (en
Inventor
Hongyan Qi
Soongyu Choi
Amal DAKKA
Gary Mitchell Karp
Jana Narasimhan
Nikolai A. Naryshkin
Anthony A. Turpoff
Marla L. Weetall
Ellen Welch
Matthew G. WOLL
Tianle Yang
Nanjing Zhang
Xiaoyan Zhang
Xin Zhao
Luke Green
Emmanuel Pinard
Hasane Ratni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
PTC Therapeutics Inc
Original Assignee
F Hoffmann La Roche AG
PTC Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201261597523P priority Critical
Application filed by F Hoffmann La Roche AG, PTC Therapeutics Inc filed Critical F Hoffmann La Roche AG
Priority to PCT/US2013/025292 priority patent/WO2013119916A2/en
Priority to EP13747100.9A priority patent/EP2812004B1/en
Publication of EP3406252A1 publication Critical patent/EP3406252A1/en
Application granted granted Critical
Publication of EP3406252B1 publication Critical patent/EP3406252B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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