JP2021533197A5 - - Google Patents

Info

Publication number
JP2021533197A5
JP2021533197A5 JP2021529257A JP2021529257A JP2021533197A5 JP 2021533197 A5 JP2021533197 A5 JP 2021533197A5 JP 2021529257 A JP2021529257 A JP 2021529257A JP 2021529257 A JP2021529257 A JP 2021529257A JP 2021533197 A5 JP2021533197 A5 JP 2021533197A5
Authority
JP
Japan
Prior art keywords
oligonucleotide
complex
transferrin receptor
complex according
receptor antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021529257A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021533197A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/044960 external-priority patent/WO2020028841A1/en
Publication of JP2021533197A publication Critical patent/JP2021533197A/ja
Publication of JP2021533197A5 publication Critical patent/JP2021533197A5/ja
Priority to JP2025006544A priority Critical patent/JP2025071093A/ja
Pending legal-status Critical Current

Links

JP2021529257A 2018-08-02 2019-08-02 ポンペ病を処置するための筋標的化複合体およびそれらの使用 Pending JP2021533197A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025006544A JP2025071093A (ja) 2018-08-02 2025-01-17 ポンペ病を処置するための筋標的化複合体およびそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862713959P 2018-08-02 2018-08-02
US62/713,959 2018-08-02
PCT/US2019/044960 WO2020028841A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating pompe disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025006544A Division JP2025071093A (ja) 2018-08-02 2025-01-17 ポンペ病を処置するための筋標的化複合体およびそれらの使用

Publications (2)

Publication Number Publication Date
JP2021533197A JP2021533197A (ja) 2021-12-02
JP2021533197A5 true JP2021533197A5 (enExample) 2022-08-10

Family

ID=69230844

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021529257A Pending JP2021533197A (ja) 2018-08-02 2019-08-02 ポンペ病を処置するための筋標的化複合体およびそれらの使用
JP2025006544A Pending JP2025071093A (ja) 2018-08-02 2025-01-17 ポンペ病を処置するための筋標的化複合体およびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025006544A Pending JP2025071093A (ja) 2018-08-02 2025-01-17 ポンペ病を処置するための筋標的化複合体およびそれらの使用

Country Status (9)

Country Link
US (1) US20210317226A1 (enExample)
EP (1) EP3830127A4 (enExample)
JP (2) JP2021533197A (enExample)
KR (1) KR20210054513A (enExample)
CN (2) CN118662653A (enExample)
CA (1) CA3108285A1 (enExample)
EA (1) EA202190417A1 (enExample)
IL (1) IL280483A (enExample)
WO (1) WO2020028841A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3635009T3 (da) 2017-06-07 2026-03-30 Regeneron Pharma Sammensætninger og fremgangsmåder til internalisering af enzymer
US12258597B2 (en) 2018-02-07 2025-03-25 Regeneron Pharmaceuticals, Inc. Methods and compositions for therapeutic protein delivery
BR112020023145A2 (pt) 2018-05-17 2021-02-02 Regeneron Pharmaceuticals, Inc. anticorpo anti-cd63 ou fragmento de ligação ao antígeno do mesmo, molécula de ligação ao antígeno biespecífica, proteína terapêutica de múltiplos domínios, polinucleotídeo composição farmacêutica, e, composto
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
WO2021226107A1 (en) * 2020-05-05 2021-11-11 Avidity Biosciences, Inc. Compositions and methods of treating pompe disease
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
WO2023034409A1 (en) 2021-09-01 2023-03-09 Biogen Ma Inc. Anti-transferrin receptor antibodies and uses thereof
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
KR20250058123A (ko) * 2022-07-29 2025-04-29 리제너론 파마슈티칼스 인코포레이티드 항-TfR:페이로드 융합 및 이의 사용 방법
WO2025160275A1 (en) 2024-01-24 2025-07-31 Arrowhead Pharmaceuticals, Inc. Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1620564A4 (en) * 2003-04-18 2008-03-12 Cytovia Inc METHOD FOR TREATING DISEASES RESPONSING TO APOPTOSIS INDUCTION AND SCREENING TESTS
EP3795687A1 (en) * 2014-05-23 2021-03-24 Genzyme Corporation Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides
DK3386534T3 (da) * 2015-12-08 2020-11-30 Regeneron Pharma Sammensætninger og fremgangsmåder til internalisering af enzymer
WO2017184529A1 (en) * 2016-04-18 2017-10-26 Sarepta Therapeutics, Inc. Antisense oligomers and methods of using the same for treating diseases associated with the acid alpha-glucosidase gene
DK3473270T5 (da) * 2016-06-20 2024-09-09 Genahead Bio Inc Konjugat af antistof-lægemiddel

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