JP2021532832A5 - - Google Patents
Info
- Publication number
- JP2021532832A5 JP2021532832A5 JP2021529256A JP2021529256A JP2021532832A5 JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5 JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5
- Authority
- JP
- Japan
- Prior art keywords
- complex according
- oligonucleotide
- transferrin receptor
- complex
- fxn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862714035P | 2018-08-02 | 2018-08-02 | |
| US62/714,035 | 2018-08-02 | ||
| PCT/US2019/044959 WO2020028840A1 (en) | 2018-08-02 | 2019-08-02 | Muscle targeting complexes and uses thereof for treating friedreich's ataxia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021532832A JP2021532832A (ja) | 2021-12-02 |
| JP2021532832A5 true JP2021532832A5 (enExample) | 2022-08-10 |
Family
ID=69232074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529256A Pending JP2021532832A (ja) | 2018-08-02 | 2019-08-02 | フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210308274A1 (enExample) |
| EP (1) | EP3830131A4 (enExample) |
| JP (1) | JP2021532832A (enExample) |
| KR (1) | KR20210086601A (enExample) |
| CN (1) | CN113166240A (enExample) |
| CA (1) | CA3108386A1 (enExample) |
| EA (1) | EA202190419A1 (enExample) |
| IL (1) | IL280535A (enExample) |
| WO (1) | WO2020028840A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| CA3108282A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| SG11202100928QA (en) | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| CN118251238A (zh) * | 2021-06-21 | 2024-06-25 | 达因疗法公司 | 肌肉靶向复合物及其用于治疗弗里德赖希共济失调的用途 |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| JP2024525608A (ja) | 2021-07-09 | 2024-07-12 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体および製剤 |
| WO2023034409A1 (en) | 2021-09-01 | 2023-03-09 | Biogen Ma Inc. | Anti-transferrin receptor antibodies and uses thereof |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| EP4612184A1 (en) * | 2022-11-04 | 2025-09-10 | Regeneron Pharmaceuticals, Inc. | Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle |
| WO2025160275A1 (en) | 2024-01-24 | 2025-07-31 | Arrowhead Pharmaceuticals, Inc. | Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160201064A1 (en) * | 2013-08-16 | 2016-07-14 | Rana Therapeutics, Inc. | Compositions and methods for modulating expression of frataxin |
| CA2921457A1 (en) * | 2013-08-16 | 2015-02-19 | Rana Therapeutics, Inc. | Heterochromatin forming non-coding rnas |
| US10508151B2 (en) * | 2014-11-19 | 2019-12-17 | Genentech, Inc. | Anti-transferrin receptor antibodies and methods of use |
| US20190002876A1 (en) * | 2014-12-09 | 2019-01-03 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treatment of friedreich's ataxia |
| SG11201802408RA (en) * | 2015-11-05 | 2018-05-30 | Bamboo Therapeutics Inc | Modified friedreich ataxia genes and vectors for gene therapy |
| DK3473270T5 (da) * | 2016-06-20 | 2024-09-09 | Genahead Bio Inc | Konjugat af antistof-lægemiddel |
| IL280536B2 (en) * | 2018-08-02 | 2024-12-01 | Dyne Therapeutics Inc | Complexes targeting transferrin receptor and uses thereof |
-
2019
- 2019-08-02 KR KR1020217006029A patent/KR20210086601A/ko not_active Withdrawn
- 2019-08-02 WO PCT/US2019/044959 patent/WO2020028840A1/en not_active Ceased
- 2019-08-02 EA EA202190419A patent/EA202190419A1/ru unknown
- 2019-08-02 CA CA3108386A patent/CA3108386A1/en active Pending
- 2019-08-02 EP EP19845433.2A patent/EP3830131A4/en active Pending
- 2019-08-02 US US17/265,019 patent/US20210308274A1/en not_active Abandoned
- 2019-08-02 CN CN201980064588.8A patent/CN113166240A/zh active Pending
- 2019-08-02 JP JP2021529256A patent/JP2021532832A/ja active Pending
-
2021
- 2021-01-31 IL IL280535A patent/IL280535A/en unknown