JP2021532832A5 - - Google Patents
Info
- Publication number
- JP2021532832A5 JP2021532832A5 JP2021529256A JP2021529256A JP2021532832A5 JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5 JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5
- Authority
- JP
- Japan
- Prior art keywords
- complex according
- oligonucleotide
- transferrin receptor
- complex
- fxn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862714035P | 2018-08-02 | 2018-08-02 | |
| US62/714,035 | 2018-08-02 | ||
| PCT/US2019/044959 WO2020028840A1 (en) | 2018-08-02 | 2019-08-02 | Muscle targeting complexes and uses thereof for treating friedreich's ataxia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021532832A JP2021532832A (ja) | 2021-12-02 |
| JP2021532832A5 true JP2021532832A5 (enExample) | 2022-08-10 |
Family
ID=69232074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529256A Pending JP2021532832A (ja) | 2018-08-02 | 2019-08-02 | フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210308274A1 (enExample) |
| EP (1) | EP3830131A4 (enExample) |
| JP (1) | JP2021532832A (enExample) |
| KR (1) | KR20210086601A (enExample) |
| CN (1) | CN113166240A (enExample) |
| CA (1) | CA3108386A1 (enExample) |
| EA (1) | EA202190419A1 (enExample) |
| IL (1) | IL280535A (enExample) |
| WO (1) | WO2020028840A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7611825B2 (ja) | 2018-08-02 | 2025-01-10 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US20220193250A1 (en) | 2018-08-02 | 2022-06-23 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US12624120B2 (en) | 2020-01-31 | 2026-05-12 | Dyne Therapeutics, Inc. | Anti-transferrin receptor (TfR) antibody and uses thereof |
| EP4359008A4 (en) * | 2021-06-21 | 2026-05-06 | Dyne Therapeutics Inc | MUSCLE TARGETTING COMPLEXES AND THEIR USE TO TREAT FRIEDREICH'S ATAXIA |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| CN117980006A (zh) | 2021-07-09 | 2024-05-03 | 达因疗法公司 | 用于治疗肌养蛋白病的肌肉靶向复合物和制剂 |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| MX2024002753A (es) | 2021-09-01 | 2024-05-20 | Biogen Ma Inc | Anticuerpos anti receptor de transferrina y usos de los mismos. |
| KR20250004770A (ko) | 2022-04-15 | 2025-01-08 | 다인 세라퓨틱스, 인크. | 근긴장성 이영양증을 치료하기 위한 근육 표적화 복합체 및 제제 |
| CN120693347A (zh) * | 2022-11-04 | 2025-09-23 | 瑞泽恩制药公司 | 钙电压门控通道辅助亚基γ1(CACNG1)结合蛋白和CACNG1介导的向骨骼肌的递送 |
| WO2025160275A1 (en) | 2024-01-24 | 2025-07-31 | Arrowhead Pharmaceuticals, Inc. | Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015023939A1 (en) * | 2013-08-16 | 2015-02-19 | Rana Therapeutics, Inc. | Compositions and methods for modulating expression of frataxin |
| WO2015023937A1 (en) * | 2013-08-16 | 2015-02-19 | Rana Therapeutics, Inc. | Heterochromatin forming non-coding rnas |
| JP6779876B2 (ja) * | 2014-11-19 | 2020-11-04 | ジェネンテック， インコーポレイテッド | 抗トランスフェリン受容体抗体及びその使用方法 |
| US20190002876A1 (en) * | 2014-12-09 | 2019-01-03 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treatment of friedreich's ataxia |
| PE20181156A1 (es) * | 2015-11-05 | 2018-07-19 | Bamboo Therapeutics Inc | Genes de ataxia de friedreich modificados y vectores para terapia genica |
| US20190240346A1 (en) * | 2016-06-20 | 2019-08-08 | Genahead Bio, Inc. | Antibody-drug conjugate |
| MX2021001282A (es) * | 2018-08-02 | 2021-07-15 | Dyne Therapeutics Inc | Complejos dirigidos al músculo y sus usos. |
-
2019
- 2019-08-02 US US17/265,019 patent/US20210308274A1/en not_active Abandoned
- 2019-08-02 KR KR1020217006029A patent/KR20210086601A/ko not_active Withdrawn
- 2019-08-02 EA EA202190419A patent/EA202190419A1/ru unknown
- 2019-08-02 WO PCT/US2019/044959 patent/WO2020028840A1/en not_active Ceased
- 2019-08-02 JP JP2021529256A patent/JP2021532832A/ja active Pending
- 2019-08-02 EP EP19845433.2A patent/EP3830131A4/en active Pending
- 2019-08-02 CN CN201980064588.8A patent/CN113166240A/zh active Pending
- 2019-08-02 CA CA3108386A patent/CA3108386A1/en active Pending
-
2021
- 2021-01-31 IL IL280535A patent/IL280535A/en unknown