JP2024525614A5 - - Google Patents
Info
- Publication number
- JP2024525614A5 JP2024525614A5 JP2024500493A JP2024500493A JP2024525614A5 JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5 JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5
- Authority
- JP
- Japan
- Prior art keywords
- complex
- complex according
- seq
- mstn
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163220071P | 2021-07-09 | 2021-07-09 | |
| US202163220039P | 2021-07-09 | 2021-07-09 | |
| US202163220085P | 2021-07-09 | 2021-07-09 | |
| US202163220056P | 2021-07-09 | 2021-07-09 | |
| US202163220050P | 2021-07-09 | 2021-07-09 | |
| US63/220,071 | 2021-07-09 | ||
| US63/220,050 | 2021-07-09 | ||
| US63/220,039 | 2021-07-09 | ||
| US63/220,056 | 2021-07-09 | ||
| US63/220,085 | 2021-07-09 | ||
| PCT/US2022/073362 WO2023283531A2 (en) | 2021-07-09 | 2022-07-01 | Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024525614A JP2024525614A (ja) | 2024-07-12 |
| JP2024525614A5 true JP2024525614A5 (enExample) | 2025-07-09 |
Family
ID=84802048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024500493A Pending JP2024525614A (ja) | 2021-07-09 | 2022-07-01 | 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240382513A1 (enExample) |
| EP (1) | EP4366774A4 (enExample) |
| JP (1) | JP2024525614A (enExample) |
| CA (1) | CA3226361A1 (enExample) |
| WO (1) | WO2023283531A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4169576A1 (en) | 2018-03-23 | 2023-04-26 | University of Massachusetts | Gene therapeutics for treating bone disorders |
| CA3108282A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| SG11202100928QA (en) | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| EP4185320A4 (en) * | 2020-07-23 | 2025-10-08 | Dyne Therapeutics Inc | MUSCLE TARGETING COMPLEXES AND THEIR USES IN THE TREATMENT OF MUSCLE ATROPHY |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| JP2024525608A (ja) | 2021-07-09 | 2024-07-12 | ダイン セラピューティクス,インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体および製剤 |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| EP4698654A1 (en) * | 2023-04-20 | 2026-02-25 | University of Massachusetts | Rnas targeting activin a subunits |
| AU2024299328A1 (en) | 2023-07-21 | 2026-01-22 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7553485B2 (en) * | 2002-01-18 | 2009-06-30 | Pierre Fabre Medicament | Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof |
| EP1996215A2 (en) * | 2006-02-28 | 2008-12-03 | Trustees Of Boston University | Metabolic regulators and uses thereof |
| KR20120115511A (ko) * | 2010-01-15 | 2012-10-18 | 교와 핫꼬 기린 가부시키가이샤 | 항시스템 asc 아미노산 트랜스포터 2(asct2) 항체 |
| FR3049951A1 (fr) * | 2016-04-12 | 2017-10-13 | Univ Rabelais Francois | Nouvelles constructions peptidiques et leur utilisation dans le traitement de la toxoplasmose |
| WO2018068182A1 (en) * | 2016-10-10 | 2018-04-19 | Crown Bioscience (Taicang) Inc. | Novel anti-ctla4 antibodies |
| EP3829645A4 (en) * | 2018-08-02 | 2022-05-18 | Dyne Therapeutics, Inc. | MUSCLE TARGETING COMPLEXES AND THEIR USES FOR THE TREATMENT OF PROGRESSIVE FIBRODYSPLASIA OSSIFIANS |
| CN116194470B (zh) * | 2020-07-23 | 2025-10-03 | 达因疗法公司 | 肌肉靶向复合物及其用途 |
| EP4185320A4 (en) * | 2020-07-23 | 2025-10-08 | Dyne Therapeutics Inc | MUSCLE TARGETING COMPLEXES AND THEIR USES IN THE TREATMENT OF MUSCLE ATROPHY |
-
2022
- 2022-07-01 US US18/577,382 patent/US20240382513A1/en active Pending
- 2022-07-01 WO PCT/US2022/073362 patent/WO2023283531A2/en not_active Ceased
- 2022-07-01 JP JP2024500493A patent/JP2024525614A/ja active Pending
- 2022-07-01 CA CA3226361A patent/CA3226361A1/en active Pending
- 2022-07-01 EP EP22838534.0A patent/EP4366774A4/en active Pending
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