JP2024525614A5 - - Google Patents

Info

Publication number
JP2024525614A5
JP2024525614A5 JP2024500493A JP2024500493A JP2024525614A5 JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5 JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5
Authority
JP
Japan
Prior art keywords
complex
complex according
seq
mstn
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500493A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525614A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073362 external-priority patent/WO2023283531A2/en
Publication of JP2024525614A publication Critical patent/JP2024525614A/ja
Publication of JP2024525614A5 publication Critical patent/JP2024525614A5/ja
Pending legal-status Critical Current

Links

JP2024500493A 2021-07-09 2022-07-01 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 Pending JP2024525614A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163220071P 2021-07-09 2021-07-09
US202163220039P 2021-07-09 2021-07-09
US202163220085P 2021-07-09 2021-07-09
US202163220056P 2021-07-09 2021-07-09
US202163220050P 2021-07-09 2021-07-09
US63/220,071 2021-07-09
US63/220,050 2021-07-09
US63/220,039 2021-07-09
US63/220,056 2021-07-09
US63/220,085 2021-07-09
PCT/US2022/073362 WO2023283531A2 (en) 2021-07-09 2022-07-01 Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health

Publications (2)

Publication Number Publication Date
JP2024525614A JP2024525614A (ja) 2024-07-12
JP2024525614A5 true JP2024525614A5 (enExample) 2025-07-09

Family

ID=84802048

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500493A Pending JP2024525614A (ja) 2021-07-09 2022-07-01 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用

Country Status (5)

Country Link
US (1) US20240382513A1 (enExample)
EP (1) EP4366774A4 (enExample)
JP (1) JP2024525614A (enExample)
CA (1) CA3226361A1 (enExample)
WO (1) WO2023283531A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4169576A1 (en) 2018-03-23 2023-04-26 University of Massachusetts Gene therapeutics for treating bone disorders
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
EP4185320A4 (en) * 2020-07-23 2025-10-08 Dyne Therapeutics Inc MUSCLE TARGETING COMPLEXES AND THEIR USES IN THE TREATMENT OF MUSCLE ATROPHY
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
EP4698654A1 (en) * 2023-04-20 2026-02-25 University of Massachusetts Rnas targeting activin a subunits
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553485B2 (en) * 2002-01-18 2009-06-30 Pierre Fabre Medicament Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof
EP1996215A2 (en) * 2006-02-28 2008-12-03 Trustees Of Boston University Metabolic regulators and uses thereof
KR20120115511A (ko) * 2010-01-15 2012-10-18 교와 핫꼬 기린 가부시키가이샤 항시스템 asc 아미노산 트랜스포터 2(asct2) 항체
FR3049951A1 (fr) * 2016-04-12 2017-10-13 Univ Rabelais Francois Nouvelles constructions peptidiques et leur utilisation dans le traitement de la toxoplasmose
WO2018068182A1 (en) * 2016-10-10 2018-04-19 Crown Bioscience (Taicang) Inc. Novel anti-ctla4 antibodies
EP3829645A4 (en) * 2018-08-02 2022-05-18 Dyne Therapeutics, Inc. MUSCLE TARGETING COMPLEXES AND THEIR USES FOR THE TREATMENT OF PROGRESSIVE FIBRODYSPLASIA OSSIFIANS
CN116194470B (zh) * 2020-07-23 2025-10-03 达因疗法公司 肌肉靶向复合物及其用途
EP4185320A4 (en) * 2020-07-23 2025-10-08 Dyne Therapeutics Inc MUSCLE TARGETING COMPLEXES AND THEIR USES IN THE TREATMENT OF MUSCLE ATROPHY

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