JP2024525614A5 - - Google Patents
Info
- Publication number
- JP2024525614A5 JP2024525614A5 JP2024500493A JP2024500493A JP2024525614A5 JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5 JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024525614 A5 JP2024525614 A5 JP 2024525614A5
- Authority
- JP
- Japan
- Prior art keywords
- complex
- complex according
- seq
- mstn
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163220085P | 2021-07-09 | 2021-07-09 | |
| US202163220050P | 2021-07-09 | 2021-07-09 | |
| US202163220039P | 2021-07-09 | 2021-07-09 | |
| US202163220071P | 2021-07-09 | 2021-07-09 | |
| US202163220056P | 2021-07-09 | 2021-07-09 | |
| US63/220,071 | 2021-07-09 | ||
| US63/220,050 | 2021-07-09 | ||
| US63/220,039 | 2021-07-09 | ||
| US63/220,085 | 2021-07-09 | ||
| US63/220,056 | 2021-07-09 | ||
| PCT/US2022/073362 WO2023283531A2 (en) | 2021-07-09 | 2022-07-01 | Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024525614A JP2024525614A (ja) | 2024-07-12 |
| JP2024525614A5 true JP2024525614A5 (enExample) | 2025-07-09 |
Family
ID=84802048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024500493A Pending JP2024525614A (ja) | 2021-07-09 | 2022-07-01 | 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240382513A1 (enExample) |
| EP (1) | EP4366774A4 (enExample) |
| JP (1) | JP2024525614A (enExample) |
| CA (1) | CA3226361A1 (enExample) |
| WO (1) | WO2023283531A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3768386A4 (en) | 2018-03-23 | 2022-04-13 | University of Massachusetts | GENE THERAPY FOR THE TREATMENT OF BONE DISORDERS |
| JP7611825B2 (ja) | 2018-08-02 | 2025-01-10 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US20220193250A1 (en) | 2018-08-02 | 2022-06-23 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US12624120B2 (en) | 2020-01-31 | 2026-05-12 | Dyne Therapeutics, Inc. | Anti-transferrin receptor (TfR) antibody and uses thereof |
| US20230346966A1 (en) * | 2020-07-23 | 2023-11-02 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof in treating muscle atrophy |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| CN117980006A (zh) | 2021-07-09 | 2024-05-03 | 达因疗法公司 | 用于治疗肌养蛋白病的肌肉靶向复合物和制剂 |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| KR20250004770A (ko) | 2022-04-15 | 2025-01-08 | 다인 세라퓨틱스, 인크. | 근긴장성 이영양증을 치료하기 위한 근육 표적화 복합체 및 제제 |
| WO2024220758A1 (en) * | 2023-04-20 | 2024-10-24 | University Of Massachusetts | Rnas targeting activin a subunits |
| KR20260044219A (ko) | 2023-07-21 | 2026-04-01 | 매로우 테라퓨틱스, 인크. | 조혈 세포 표적화 접합체 및 관련 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7553485B2 (en) * | 2002-01-18 | 2009-06-30 | Pierre Fabre Medicament | Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof |
| KR20080108487A (ko) * | 2006-02-28 | 2008-12-15 | 트르스티스 오브 보스톤 유니버시티 | 대사 조절인자 및 그의 용도 |
| JP5812869B2 (ja) * | 2010-01-15 | 2015-11-17 | 協和発酵キリン株式会社 | 抗システムａｓｃアミノ酸トランスポーター２（ａｓｃｔ２）抗体 |
| FR3049951A1 (fr) * | 2016-04-12 | 2017-10-13 | Univ Rabelais Francois | Nouvelles constructions peptidiques et leur utilisation dans le traitement de la toxoplasmose |
| US10618962B2 (en) * | 2016-10-10 | 2020-04-14 | Crown Bioscience (Taicang) Inc. | Anti-CTLA4 antibodies |
| BR112019012328A2 (pt) * | 2016-12-15 | 2019-11-19 | Abbvie Biotherapeutics Inc | anticorpos anti-ox40 e seus usos |
| BR112020007302B1 (pt) * | 2017-10-14 | 2023-01-31 | Abbvie Inc. | Anticorpos ativáveis conjugados anti-cd71, método para fabrica-los, composição farmacêutica e kit que compreende os mesmos, usos dos ditos anticorpos, bem como método in vitro para detectar a presença ou ausência do agente de clivagem na amostra |
| JP7611825B2 (ja) * | 2018-08-02 | 2025-01-10 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用 |
| EA202190418A1 (ru) * | 2018-08-02 | 2021-06-23 | Дайн Терапьютикс, Инк. | Мышечно-специфические комлексы и их применение в лечении прогрессирующей оссифицирующей фибродисплазии |
| MX2021001282A (es) * | 2018-08-02 | 2021-07-15 | Dyne Therapeutics Inc | Complejos dirigidos al músculo y sus usos. |
| AU2021313058A1 (en) * | 2020-07-23 | 2023-03-30 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof |
| US20230346966A1 (en) * | 2020-07-23 | 2023-11-02 | Dyne Therapeutics, Inc. | Muscle-targeting complexes and uses thereof in treating muscle atrophy |
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2022
- 2022-07-01 US US18/577,382 patent/US20240382513A1/en active Pending
- 2022-07-01 CA CA3226361A patent/CA3226361A1/en active Pending
- 2022-07-01 EP EP22838534.0A patent/EP4366774A4/en active Pending
- 2022-07-01 WO PCT/US2022/073362 patent/WO2023283531A2/en not_active Ceased
- 2022-07-01 JP JP2024500493A patent/JP2024525614A/ja active Pending