JP2024525614A - 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 - Google Patents

筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 Download PDF

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JP2024525614A
JP2024525614A JP2024500493A JP2024500493A JP2024525614A JP 2024525614 A JP2024525614 A JP 2024525614A JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024500493 A JP2024500493 A JP 2024500493A JP 2024525614 A JP2024525614 A JP 2024525614A
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seq
amino acid
acid sequence
optionally
light chain
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JP2024525614A5 (enExample
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サブラマニアン，ロメシュ，アール．
カタナニ，モハマド，ティー．
デジャルダン，コディ，エー．
ブラウン，ダンカン
コテリアンスキー，ヴィクター
ウィーデン，ティモシー
クイン，ブレンダン
ナジム，ジョン
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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JP2024500493A 2021-07-09 2022-07-01 筋標的化複合体および筋肉の健康に関連する遺伝子の調整のためのその使用 Pending JP2024525614A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163220071P 2021-07-09 2021-07-09
US202163220039P 2021-07-09 2021-07-09
US202163220085P 2021-07-09 2021-07-09
US202163220056P 2021-07-09 2021-07-09
US202163220050P 2021-07-09 2021-07-09
US63/220,071 2021-07-09
US63/220,050 2021-07-09
US63/220,039 2021-07-09
US63/220,056 2021-07-09
US63/220,085 2021-07-09
PCT/US2022/073362 WO2023283531A2 (en) 2021-07-09 2022-07-01 Muscle targeting complexes and uses thereof for modulation of genes associated with muscle health

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JP2024525614A true JP2024525614A (ja) 2024-07-12
JP2024525614A5 JP2024525614A5 (enExample) 2025-07-09

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US (1) US20240382513A1 (enExample)
EP (1) EP4366774A4 (enExample)
JP (1) JP2024525614A (enExample)
CA (1) CA3226361A1 (enExample)
WO (1) WO2023283531A2 (enExample)

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Publication number Priority date Publication date Assignee Title
EP4169576A1 (en) 2018-03-23 2023-04-26 University of Massachusetts Gene therapeutics for treating bone disorders
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
EP4185320A4 (en) * 2020-07-23 2025-10-08 Dyne Therapeutics Inc MUSCLE TARGETING COMPLEXES AND THEIR USES IN THE TREATMENT OF MUSCLE ATROPHY
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
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