JP2021532832A - フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 - Google Patents

フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 Download PDF

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JP2021532832A
JP2021532832A JP2021529256A JP2021529256A JP2021532832A JP 2021532832 A JP2021532832 A JP 2021532832A JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021532832 A JP2021532832 A JP 2021532832A
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antibody
complex
muscle
oligonucleotide
transferrin receptor
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JPWO2020028840A5 (enExample
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スブラマニアン，ロメシ，アール．
カタナニ，モハメド，ティー．
ウィーデン，ティモシー
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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JP2021529256A 2018-08-02 2019-08-02 フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 Pending JP2021532832A (ja)

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US201862714035P 2018-08-02 2018-08-02
US62/714,035 2018-08-02
PCT/US2019/044959 WO2020028840A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating friedreich's ataxia

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JP2021532832A true JP2021532832A (ja) 2021-12-02
JPWO2020028840A5 JPWO2020028840A5 (enExample) 2022-08-10

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CN (1) CN113166240A (enExample)
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EA (1) EA202190419A1 (enExample)
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EA202190416A1 (ru) 2018-08-02 2021-06-23 Дайн Терапьютикс, Инк. Мышечно-специфические комлексы и их применение для лечения плече-лопаточно-лицевой мышечной дистрофии
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
WO2020028832A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
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