CN113166240A - 肌肉靶向复合物及其用于治疗弗里德赖希共济失调的用途 - Google Patents

肌肉靶向复合物及其用于治疗弗里德赖希共济失调的用途 Download PDF

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CN113166240A
CN113166240A CN201980064588.8A CN201980064588A CN113166240A CN 113166240 A CN113166240 A CN 113166240A CN 201980064588 A CN201980064588 A CN 201980064588A CN 113166240 A CN113166240 A CN 113166240A
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complex
antibody
muscle
transferrin receptor
oligonucleotide
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罗梅什·R·苏布拉马尼亚
穆罕默德·T·卡塔纳尼
蒂莫西·威登
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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CN201980064588.8A 2018-08-02 2019-08-02 肌肉靶向复合物及其用于治疗弗里德赖希共济失调的用途 Pending CN113166240A (zh)

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US201862714035P 2018-08-02 2018-08-02
US62/714,035 2018-08-02
PCT/US2019/044959 WO2020028840A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating friedreich's ataxia

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EA (1) EA202190419A1 (enExample)
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US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
EP3830259A4 (en) 2018-08-02 2022-05-04 Dyne Therapeutics, Inc. MUSCLE TARGETED COMPLEXES AND THEIR USES IN THE TREATMENT OF FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
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