KR20210054513A - 근육 표적화 복합체 및 폼페병을 치료하기 위한 그의 용도 - Google Patents

근육 표적화 복합체 및 폼페병을 치료하기 위한 그의 용도 Download PDF

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KR20210054513A
KR20210054513A KR1020217005994A KR20217005994A KR20210054513A KR 20210054513 A KR20210054513 A KR 20210054513A KR 1020217005994 A KR1020217005994 A KR 1020217005994A KR 20217005994 A KR20217005994 A KR 20217005994A KR 20210054513 A KR20210054513 A KR 20210054513A
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South Korea
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complex
muscle
antibody
transferrin receptor
oligonucleotide
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KR1020217005994A
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Korean (ko)
Inventor
로메쉬 알. 서브라마니안
모하메드 티. 카타나니
티모시 위든
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다인 세라퓨틱스, 인크.
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Publication of KR20210054513A publication Critical patent/KR20210054513A/ko
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2881—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD71
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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KR1020217005994A 2018-08-02 2019-08-02 근육 표적화 복합체 및 폼페병을 치료하기 위한 그의 용도 Pending KR20210054513A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862713959P 2018-08-02 2018-08-02
US62/713,959 2018-08-02
PCT/US2019/044960 WO2020028841A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating pompe disease

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KR20210054513A true KR20210054513A (ko) 2021-05-13

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US (1) US20210317226A1 (enExample)
EP (1) EP3830127A4 (enExample)
JP (2) JP2021533197A (enExample)
KR (1) KR20210054513A (enExample)
CN (2) CN118662653A (enExample)
CA (1) CA3108285A1 (enExample)
EA (1) EA202190417A1 (enExample)
IL (1) IL280483A (enExample)
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MA50546A (fr) 2017-06-07 2020-09-16 Regeneron Pharma Compositions et méthodes pour l'internalisation d'enzymes
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