JP2021532059A5 - - Google Patents
Info
- Publication number
- JP2021532059A5 JP2021532059A5 JP2020554461A JP2020554461A JP2021532059A5 JP 2021532059 A5 JP2021532059 A5 JP 2021532059A5 JP 2020554461 A JP2020554461 A JP 2020554461A JP 2020554461 A JP2020554461 A JP 2020554461A JP 2021532059 A5 JP2021532059 A5 JP 2021532059A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- halo
- pharmaceutical composition
- cycloalkyl
- group
- Prior art date
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862653249P | 2018-04-05 | 2018-04-05 | |
| US62/653,249 | 2018-04-05 | ||
| US201862694729P | 2018-07-06 | 2018-07-06 | |
| US62/694,729 | 2018-07-06 | ||
| PCT/US2019/026112 WO2019195761A2 (en) | 2018-04-05 | 2019-04-05 | Pharmacological agents for treating ocular diseases |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021532059A JP2021532059A (ja) | 2021-11-25 |
| JP2021532059A5 true JP2021532059A5 (https=) | 2022-04-13 |
| JPWO2019195761A5 JPWO2019195761A5 (https=) | 2022-04-13 |
| JP7532259B2 JP7532259B2 (ja) | 2024-08-13 |
Family
ID=68101528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554461A Active JP7532259B2 (ja) | 2018-04-05 | 2019-04-05 | 眼疾患治療薬剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11872236B2 (https=) |
| JP (1) | JP7532259B2 (https=) |
| CN (1) | CN112601513B (https=) |
| BR (1) | BR112020020351A2 (https=) |
| MX (1) | MX2020010502A (https=) |
| WO (1) | WO2019195761A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120097859A (zh) * | 2019-02-19 | 2025-06-06 | 加利福尼亚大学董事会 | Nurr1受体调节剂 |
| EP3976017A4 (en) * | 2019-05-31 | 2023-06-14 | Plex Pharmaceuticals, Inc. | PHARMACOLOGICAL SUBSTANCES FOR THE TREATMENT OF PROTEIN AGGREGATION DISEASES OF THE EYE |
| WO2021086834A1 (en) * | 2019-10-28 | 2021-05-06 | Kebotix, Inc. | Electronic control of transmittance of visible and near-infrared radiation |
| WO2022098847A1 (en) * | 2020-11-04 | 2022-05-12 | Corino Therapeutics, Inc. | Tolcapone analogs and methods of use |
| CN116963727A (zh) * | 2020-11-13 | 2023-10-27 | 普莱克斯医药公司 | 用于治疗眼部病症的药剂 |
| JP2023549533A (ja) * | 2020-11-13 | 2023-11-27 | プレックス ファーマスーティカルズ，インク | 眼の状態を処置するための薬理剤 |
| US20250019352A1 (en) * | 2021-06-29 | 2025-01-16 | Plex Pharmaceuticals, Inc. | Pharmacological agents for treating ophthalmic diseases |
| GB202204798D0 (en) | 2022-04-01 | 2022-05-18 | Bial Portela & Ca Sa | Prodrugs of opicapone |
| WO2024123100A1 (ko) * | 2022-12-09 | 2024-06-13 | 경희대학교 산학협력단 | 신규 아밀로이드-베타 응집체 분해제와 이를 이용한 뇌 표적화 약물 전달 시스템 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5236952A (en) * | 1986-03-11 | 1993-08-17 | Hoffmann-La Roche Inc. | Catechol derivatives |
| DK175069B1 (da) | 1986-03-11 | 2004-05-24 | Hoffmann La Roche | Pyrocatecholderivater |
| JPH1036257A (ja) * | 1996-05-22 | 1998-02-10 | Kikkoman Corp | メイラード反応阻害剤 |
| ID19540A (id) | 1997-01-22 | 1998-07-23 | Hoffmann La Roche | Metode pembuatan turunan-turunan benzofenon |
| JP2000256259A (ja) * | 1999-03-11 | 2000-09-19 | Nippon Zoki Pharmaceut Co Ltd | メイラード反応阻害剤 |
| US8299079B2 (en) | 2009-05-22 | 2012-10-30 | Kaufman Herbert E | Preparations and methods for ameliorating or reducing presbyopia |
| WO2011047412A1 (en) * | 2009-10-22 | 2011-04-28 | The Heart Research Institute Ltd | Tyrosine and l-dopa for reducing l-dopa incorporation into proteins |
| WO2011140333A1 (en) * | 2010-05-07 | 2011-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Identification of stabilizers of multimeric proteins |
| WO2014147464A2 (en) | 2013-03-20 | 2014-09-25 | Ra Chem Pharma Limited | Novel process for the preparation of tolcapone |
| WO2015095257A2 (en) * | 2013-12-18 | 2015-06-25 | Emory University | Managing visual dysfunction or loss of vision for diabetic subjects |
| RU2724190C2 (ru) | 2014-02-08 | 2020-06-23 | Дженентек, Инк. | Способы лечения болезни альцгеймера |
| KR20170048426A (ko) * | 2014-08-22 | 2017-05-08 | 광저우 캉루이 바이오로지컬 파마슈티컬 테크놀로지 씨오., 엘티디. | 시각 장애를 치료하기 위한 조성물 및 방법 |
| WO2017039525A1 (en) | 2015-09-04 | 2017-03-09 | Lobsor Pharmaceuticals Aktiebolag | Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor |
| CN116963727A (zh) | 2020-11-13 | 2023-10-27 | 普莱克斯医药公司 | 用于治疗眼部病症的药剂 |
| JP2023549533A (ja) | 2020-11-13 | 2023-11-27 | プレックス ファーマスーティカルズ，インク | 眼の状態を処置するための薬理剤 |
-
2019
- 2019-04-05 WO PCT/US2019/026112 patent/WO2019195761A2/en not_active Ceased
- 2019-04-05 US US17/045,430 patent/US11872236B2/en active Active
- 2019-04-05 JP JP2020554461A patent/JP7532259B2/ja active Active
- 2019-04-05 MX MX2020010502A patent/MX2020010502A/es unknown
- 2019-04-05 BR BR112020020351-3A patent/BR112020020351A2/pt unknown
- 2019-04-05 CN CN201980037118.2A patent/CN112601513B/zh active Active
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