JP2018535261A5 - - Google Patents

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Publication number
JP2018535261A5
JP2018535261A5 JP2018545102A JP2018545102A JP2018535261A5 JP 2018535261 A5 JP2018535261 A5 JP 2018535261A5 JP 2018545102 A JP2018545102 A JP 2018545102A JP 2018545102 A JP2018545102 A JP 2018545102A JP 2018535261 A5 JP2018535261 A5 JP 2018535261A5
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JP
Japan
Prior art keywords
optionally substituted
alkylene
heteroaryl
pharmaceutically acceptable
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018545102A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018535261A (ja
JP6933384B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/061676 external-priority patent/WO2017083756A1/en
Publication of JP2018535261A publication Critical patent/JP2018535261A/ja
Publication of JP2018535261A5 publication Critical patent/JP2018535261A5/ja
Priority to JP2021131351A priority Critical patent/JP7174963B2/ja
Application granted granted Critical
Publication of JP6933384B2 publication Critical patent/JP6933384B2/ja
Priority to JP2022173717A priority patent/JP7445325B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018545102A 2015-11-13 2016-11-11 疾患の処置のための複素環化合物 Active JP6933384B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021131351A JP7174963B2 (ja) 2015-11-13 2021-08-11 疾患の処置のための複素環化合物
JP2022173717A JP7445325B2 (ja) 2015-11-13 2022-10-28 疾患の処置のための複素環化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562255041P 2015-11-13 2015-11-13
US62/255,041 2015-11-13
PCT/US2016/061676 WO2017083756A1 (en) 2015-11-13 2016-11-11 Heterocyclic compounds for the treatment of disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021131351A Division JP7174963B2 (ja) 2015-11-13 2021-08-11 疾患の処置のための複素環化合物

Publications (3)

Publication Number Publication Date
JP2018535261A JP2018535261A (ja) 2018-11-29
JP2018535261A5 true JP2018535261A5 (https=) 2019-12-19
JP6933384B2 JP6933384B2 (ja) 2021-09-08

Family

ID=58696139

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018545102A Active JP6933384B2 (ja) 2015-11-13 2016-11-11 疾患の処置のための複素環化合物
JP2021131351A Active JP7174963B2 (ja) 2015-11-13 2021-08-11 疾患の処置のための複素環化合物
JP2022173717A Active JP7445325B2 (ja) 2015-11-13 2022-10-28 疾患の処置のための複素環化合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021131351A Active JP7174963B2 (ja) 2015-11-13 2021-08-11 疾患の処置のための複素環化合物
JP2022173717A Active JP7445325B2 (ja) 2015-11-13 2022-10-28 疾患の処置のための複素環化合物

Country Status (22)

Country Link
US (5) US10683291B2 (https=)
EP (2) EP4163281A1 (https=)
JP (3) JP6933384B2 (https=)
KR (1) KR102720397B1 (https=)
CN (2) CN108463222B (https=)
AU (2) AU2016353348A1 (https=)
BR (1) BR112018009745B1 (https=)
CA (1) CA3005236C (https=)
DK (1) DK3373931T3 (https=)
ES (1) ES2932049T3 (https=)
HR (1) HRP20221417T1 (https=)
HU (1) HUE060594T2 (https=)
IL (1) IL259297B2 (https=)
LT (1) LT3373931T (https=)
MX (1) MX382092B (https=)
PL (1) PL3373931T3 (https=)
PT (1) PT3373931T (https=)
RS (1) RS63837B1 (https=)
RU (1) RU2727194C2 (https=)
SI (1) SI3373931T1 (https=)
SM (1) SMT202300062T1 (https=)
WO (1) WO2017083756A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3373931T3 (da) 2015-11-13 2022-11-28 Oppilan Pharma Ltd Heterocykliske forbindelser til behandling af sygdom
US20210163485A1 (en) * 2017-05-17 2021-06-03 Oppilan Pharma Ltd. Heterocyclic Compounds for the Treatment of Disease
US20200071327A1 (en) * 2017-05-17 2020-03-05 Oppilan Pharma Ltd. Prodrugs for the Treatment of Disease
GB201815018D0 (en) * 2018-09-14 2018-10-31 Univ Oxford Innovation Ltd Enantiomeric compounds
CN119836422A (zh) 2022-07-06 2025-04-15 奥比兰制药有限公司 S1p受体调节剂的结晶形式
CN120835886A (zh) * 2023-01-13 2025-10-24 奥比兰制药有限公司 S1p受体调节剂的制备

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
CN1859908A (zh) * 2003-10-01 2006-11-08 默克公司 作为s1p受体激动剂的3,5-芳基、杂芳基或环烷基取代的-1,2,4-噁二唑类化合物
GB0511684D0 (en) * 2005-06-08 2005-07-13 Novartis Ag Organic compounds
BRPI0612028A2 (pt) * 2005-06-08 2010-10-13 Novartis Ag oxadiazóis ou isodiazóis policìclicos e uso dos mesmos como ligantes de receptor s1p
RU2425832C2 (ru) * 2006-04-03 2011-08-10 Астеллас Фарма Инк. Гетеросоединение
SG177221A1 (en) 2006-12-15 2012-01-30 Abbott Lab Novel oxadiazole compounds
US20110207704A1 (en) 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
US20100160369A1 (en) * 2008-12-04 2010-06-24 Exelixis, Inc. S1P1 Agonists and Methods of Making And Using
WO2010117662A1 (en) 2009-03-30 2010-10-14 Exelixis, Inc. Modulators of s1p and methods of making and using
US9011494B2 (en) 2009-09-24 2015-04-21 Warsaw Orthopedic, Inc. Composite vertebral rod system and methods of use
NZ599913A (en) 2009-11-13 2014-08-29 Receptos Inc Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
JP5788507B2 (ja) * 2010-07-20 2015-09-30 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 置換3−フェニル−1,2,4−オキサジアゾール化合物
RU2014120180A (ru) 2011-10-20 2015-11-27 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Замещенные бициклические аза-гетероциклы и аналоги в качестве модуляторов сиртуина
WO2015078374A1 (en) * 2013-11-27 2015-06-04 Genentech, Inc. Substituted benzamides and methods of use thereof
DK3373931T3 (da) 2015-11-13 2022-11-28 Oppilan Pharma Ltd Heterocykliske forbindelser til behandling af sygdom

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