JP2023535453A5 - - Google Patents

Info

Publication number
JP2023535453A5
JP2023535453A5 JP2023504746A JP2023504746A JP2023535453A5 JP 2023535453 A5 JP2023535453 A5 JP 2023535453A5 JP 2023504746 A JP2023504746 A JP 2023504746A JP 2023504746 A JP2023504746 A JP 2023504746A JP 2023535453 A5 JP2023535453 A5 JP 2023535453A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
heteroaryl
pharmaceutically acceptable
stereoisomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023504746A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023535453A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/042999 external-priority patent/WO2022020730A1/en
Publication of JP2023535453A publication Critical patent/JP2023535453A/ja
Publication of JP2023535453A5 publication Critical patent/JP2023535453A5/ja
Pending legal-status Critical Current

Links

JP2023504746A 2020-07-24 2021-07-23 キナゾリノンhsd17b13阻害剤とその使用 Pending JP2023535453A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063056168P 2020-07-24 2020-07-24
US63/056,168 2020-07-24
US202063113557P 2020-11-13 2020-11-13
US63/113,557 2020-11-13
PCT/US2021/042999 WO2022020730A1 (en) 2020-07-24 2021-07-23 Quinazolinone hsd17b13 inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2023535453A JP2023535453A (ja) 2023-08-17
JP2023535453A5 true JP2023535453A5 (https=) 2024-07-18

Family

ID=79728363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023504746A Pending JP2023535453A (ja) 2020-07-24 2021-07-23 キナゾリノンhsd17b13阻害剤とその使用

Country Status (10)

Country Link
US (1) US20230286923A1 (https=)
EP (1) EP4185380A4 (https=)
JP (1) JP2023535453A (https=)
KR (1) KR20230066554A (https=)
CN (1) CN116194440A (https=)
AU (1) AU2021310936A1 (https=)
CA (1) CA3186951A1 (https=)
IL (1) IL300107A (https=)
TW (1) TW202220964A (https=)
WO (1) WO2022020730A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN202011027502A (https=) * 2020-06-29 2021-12-31 Council Scient Ind Res
AU2021377248B2 (en) * 2020-11-13 2025-12-18 Inipharm, Inc. Dichlorophenol hsd17b13 inhibitors and uses thereof
WO2022216626A1 (en) * 2021-04-05 2022-10-13 Inipharm, Inc. Hydroxypyridine hsd17b13 inhibitors and uses thereof
CN118103038A (zh) 2021-08-20 2024-05-28 英安塔制药有限公司 17β-羟基类固醇脱氢酶13型抑制剂及其使用方法
WO2023192375A1 (en) * 2022-03-29 2023-10-05 Fl2022-001, Inc. Hsd17b13 inhibitors and uses thereof
CN114644655B (zh) * 2022-04-19 2023-10-27 湖南农业大学 一种光催化磷酰化喹唑啉酮类化合物的制备方法
EP4514805A4 (en) * 2022-04-28 2026-01-21 Enanta Pharm Inc TYPE 13 17-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS CONTAINING PYRIMIDINONE
PL4514782T3 (pl) * 2022-05-19 2026-02-23 Astrazeneca Ab Związki amidoheteroaromatyczne przydatne w leczeniu chorób wątroby
JP2025523357A (ja) 2022-06-09 2025-07-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Hsd17b13阻害剤
WO2025024682A1 (en) * 2023-07-26 2025-01-30 Inipharm, Inc. Methods of using dichlorophenol hsd17b13 inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2694711A (en) * 1952-12-02 1954-11-16 American Cyanamid Co Quinazolone antimalarial compounds
JP2005097276A (ja) * 2003-08-22 2005-04-14 Takeda Chem Ind Ltd 縮合ピリミジン誘導体およびその用途
US20070010537A1 (en) * 2004-08-20 2007-01-11 Kazumasa Hamamura Fused pyramidine derivative and use thereof
JP2008543968A (ja) * 2005-06-28 2008-12-04 オーキッド リサーチ ラボラトリーズ リミテッド 新規なピラゾロピリミジノン誘導体
ME02420B (me) * 2006-09-26 2016-09-20 Celgene Corp 5-supstituirani derivati kinazolinona kao sredstva protiv raka
US20080255161A1 (en) * 2007-04-11 2008-10-16 Dmitry Koltun 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
US20120165330A1 (en) * 2010-12-22 2012-06-28 Sirtris Pharmaceuticals, Inc. Quinazolinone and related analogs as sirtuin modulators
JP6359563B2 (ja) * 2013-01-14 2018-07-18 デュートルクス・リミテッド・ライアビリティ・カンパニーDeuteRx, LLC 3−(5置換−4−オキソキナゾリン−3(4h)−イル)−3−ジュウテロピペリジン−2,6−ジオン誘導体
US11608340B2 (en) * 2014-11-17 2023-03-21 Rhode Island Hospital Nanomaterial compositions, synthesis, and assembly
KR102331013B1 (ko) * 2016-01-14 2021-11-26 강푸 바이오파마슈티칼즈 리미티드 퀴나졸리논 유도체, 이의 제조방법, 약학 조성물 및 적용

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