JP2021531311A5 - - Google Patents
Info
- Publication number
- JP2021531311A5 JP2021531311A5 JP2021504235A JP2021504235A JP2021531311A5 JP 2021531311 A5 JP2021531311 A5 JP 2021531311A5 JP 2021504235 A JP2021504235 A JP 2021504235A JP 2021504235 A JP2021504235 A JP 2021504235A JP 2021531311 A5 JP2021531311 A5 JP 2021531311A5
- Authority
- JP
- Japan
- Prior art keywords
- membered
- alkyl
- cycloalkyl
- aryl
- substituted
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018096781 | 2018-07-24 | ||
| CNPCT/CN2018/096781 | 2018-07-24 | ||
| PCT/US2019/043112 WO2020023551A1 (en) | 2018-07-24 | 2019-07-23 | Naphthyridine compounds and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021531311A JP2021531311A (ja) | 2021-11-18 |
| JPWO2020023551A5 JPWO2020023551A5 (https=) | 2022-07-22 |
| JP2021531311A5 true JP2021531311A5 (https=) | 2022-07-22 |
| JP7386842B2 JP7386842B2 (ja) | 2023-11-27 |
Family
ID=67551416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504235A Active JP7386842B2 (ja) | 2018-07-24 | 2019-07-23 | ナフチリジン化合物およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12297210B2 (https=) |
| EP (1) | EP3826721B1 (https=) |
| JP (1) | JP7386842B2 (https=) |
| CN (1) | CN112533677A (https=) |
| TW (1) | TW202012405A (https=) |
| WO (1) | WO2020023551A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113454070A (zh) * | 2018-09-30 | 2021-09-28 | 豪夫迈·罗氏有限公司 | 噌啉化合物及用于hpk1依赖性疾患诸如癌症的治疗 |
| TWI721623B (zh) | 2018-10-31 | 2021-03-11 | 美商基利科學股份有限公司 | 經取代之6-氮雜苯并咪唑化合物 |
| TW202136261A (zh) | 2018-10-31 | 2021-10-01 | 美商基利科學股份有限公司 | 經取代之6-氮雜苯并咪唑化合物 |
| US11453681B2 (en) | 2019-05-23 | 2022-09-27 | Gilead Sciences, Inc. | Substituted eneoxindoles and uses thereof |
| EP4090663A1 (en) | 2020-01-15 | 2022-11-23 | Blueprint Medicines Corporation | Map4k1 inhibitors |
| WO2022063140A1 (en) * | 2020-09-23 | 2022-03-31 | Shenzhen Ionova Life Science Co., Ltd. | Pyrimidine and pyridine derivatives as hpk1 modulator and methods using same |
| CN114907375B (zh) * | 2021-02-07 | 2026-03-31 | 苏州信诺维医药科技股份有限公司 | 杂环化合物、其制备方法、药物组合物及应用 |
| CN114907374B (zh) * | 2021-02-07 | 2026-03-10 | 苏州信诺维医药科技股份有限公司 | 杂环化合物、其制备方法、药物组合物及应用 |
| KR20240083168A (ko) * | 2021-07-14 | 2024-06-11 | 블루프린트 메디신즈 코포레이션 | Map4k1 저해제로서의 헤테로사이클 화합물 |
| US20240336630A1 (en) * | 2021-07-15 | 2024-10-10 | Blueprint Medicines Corporation | Map4k1 inhibitors |
| WO2023001794A1 (en) | 2021-07-20 | 2023-01-26 | Astrazeneca Ab | Substituted pyrazine-2-carboxamides as hpk1 inhibitors for the treatment of cancer |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| CN104356236B (zh) | 2005-07-01 | 2020-07-03 | E.R.施贵宝&圣斯有限责任公司 | 抗程序性死亡配体1(pd-l1)的人单克隆抗体 |
| KR20100044251A (ko) | 2007-08-15 | 2010-04-29 | 싸이토키네틱스, 인코포레이티드 | 특정 화학 물질, 조성물 및 방법 |
| WO2010098788A2 (en) | 2008-08-25 | 2010-09-02 | Amplimmune, Inc. | Pd-i antagonists and methods for treating infectious disease |
| AU2009333580B2 (en) | 2008-12-09 | 2016-07-07 | Genentech, Inc. | Anti-PD-L1 antibodies and their use to enhance T-cell function |
| NZ628923A (en) | 2009-11-24 | 2016-02-26 | Medimmune Ltd | Targeted binding agents against b7-h1 |
| WO2011066342A2 (en) | 2009-11-24 | 2011-06-03 | Amplimmune, Inc. | Simultaneous inhibition of pd-l1/pd-l2 |
| US8980916B2 (en) | 2011-10-27 | 2015-03-17 | Merck Sharp & Dohme Corp. | Factor IXa inhibitors |
| RS61919B1 (sr) * | 2015-06-25 | 2021-06-30 | Univ Health Network | Inhibitori hpk1 i postupci za njihovo korišćenje |
| WO2018049214A1 (en) * | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
| US11180482B2 (en) * | 2016-11-30 | 2021-11-23 | Ariad Pharmaceuticals, Inc. | Anilinopyrimidines as haematopoietic progenitor kinase 1 (HPK1) inhibitors |
| MX2019011511A (es) * | 2017-03-30 | 2019-11-18 | Hoffmann La Roche | Naftiridinas como inhibidores de cinasa 1 progenitora hematopoyetica (hpk1). |
-
2019
- 2019-07-23 TW TW108126069A patent/TW202012405A/zh unknown
- 2019-07-23 JP JP2021504235A patent/JP7386842B2/ja active Active
- 2019-07-23 WO PCT/US2019/043112 patent/WO2020023551A1/en not_active Ceased
- 2019-07-23 EP EP19750197.6A patent/EP3826721B1/en active Active
- 2019-07-23 CN CN201980049189.4A patent/CN112533677A/zh active Pending
-
2021
- 2021-01-22 US US17/156,384 patent/US12297210B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021531311A5 (https=) | ||
| JP2021532109A5 (https=) | ||
| RU2010111551A (ru) | Замещенные индольные производные и способы их применения | |
| JP2020512974A5 (https=) | ||
| RU2010111550A (ru) | 2,3-замещенные индольные производные для лечения вирусных инфекций | |
| RU2016102036A (ru) | Производное хинолина | |
| RU2013126041A (ru) | Пиразолопиридины и пиразолопиридины и их применение в качестве ингибиторов tyk2 | |
| JP2021513534A5 (https=) | ||
| JP2012526728A5 (https=) | ||
| JP2019510798A5 (https=) | ||
| JP2017137291A5 (https=) | ||
| AR076486A1 (es) | Inhibidores de fosfoinositida 3 kinasa y composiciones farmaceuticas que los contienen. | |
| JP2009543802A5 (https=) | ||
| JP2018526367A5 (https=) | ||
| JPWO2020023560A5 (https=) | ||
| AR084976A1 (es) | Compuestos de bifenileno sustituidos y metodos de uso de los mismos para el tratamiento de enfermedades virales | |
| RU2016114866A (ru) | Замещенные аминопиримидиновые соединения и способы их использования | |
| JP2020500866A5 (https=) | ||
| JP2012505871A5 (https=) | ||
| JPWO2018183956A5 (https=) | ||
| JP2013512903A5 (https=) | ||
| JP2017523169A5 (https=) | ||
| RU2012153164A (ru) | Производные мочевины и их терапевтическое применение при лечении, среди прочего, заболеваний дыхательного пути | |
| RU2008112691A (ru) | Азотсодержащее гетероциклическое соединение и его фармацевтическое применение | |
| RU2013108348A (ru) | Конденсированные гетероарилы и их применение |