JP2021530228A5 - - Google Patents
Info
- Publication number
- JP2021530228A5 JP2021530228A5 JP2021501337A JP2021501337A JP2021530228A5 JP 2021530228 A5 JP2021530228 A5 JP 2021530228A5 JP 2021501337 A JP2021501337 A JP 2021501337A JP 2021501337 A JP2021501337 A JP 2021501337A JP 2021530228 A5 JP2021530228 A5 JP 2021530228A5
- Authority
- JP
- Japan
- Prior art keywords
- bacterial cells
- steviol glycoside
- glycosylated
- glucose
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862698617P | 2018-07-16 | 2018-07-16 | |
| US62/698,617 | 2018-07-16 | ||
| PCT/US2019/041957 WO2020018506A2 (en) | 2018-07-16 | 2019-07-16 | Production of steviol glycosides through whole cell biotransformation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021530228A JP2021530228A (ja) | 2021-11-11 |
| JP2021530228A5 true JP2021530228A5 (https=) | 2022-07-26 |
| JP7305087B2 JP7305087B2 (ja) | 2023-07-10 |
Family
ID=69164862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021501337A Active JP7305087B2 (ja) | 2018-07-16 | 2019-07-16 | 全細胞生体内変換によるステビオールグリコシドの産生 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11230724B2 (https=) |
| EP (2) | EP3824093B1 (https=) |
| JP (1) | JP7305087B2 (https=) |
| KR (1) | KR102532079B1 (https=) |
| CN (1) | CN112867799B (https=) |
| AU (1) | AU2019304965B2 (https=) |
| BR (1) | BR112021000876A2 (https=) |
| CA (1) | CA3106633A1 (https=) |
| ES (1) | ES3013059T3 (https=) |
| IL (1) | IL280151A (https=) |
| MX (1) | MX2021000605A (https=) |
| MY (1) | MY204735A (https=) |
| SG (1) | SG11202100450TA (https=) |
| WO (1) | WO2020018506A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111868252B (zh) * | 2018-03-12 | 2025-06-03 | 科纳根公司 | 甜菊糖苷莱苞迪苷j和莱苞迪苷n的生物合成生产 |
| AU2019304965B2 (en) * | 2018-07-16 | 2025-04-24 | Manus Bio, Inc. | Production of steviol glycosides through whole cell biotransformation |
| CN113302298B (zh) | 2018-11-09 | 2025-02-25 | 银杏生物制品公司 | 罗汉果甙的生物合成 |
| CN109402152B (zh) * | 2018-11-09 | 2021-08-13 | 沈阳农业大学 | 一种表达制备udp-葡萄糖-4-差向异构酶的方法 |
| CN109295087B (zh) * | 2018-11-09 | 2021-08-24 | 沈阳农业大学 | 一种表达制备udp-葡萄糖-己糖-1-磷酸尿苷酰转移酶的方法 |
| WO2020264179A1 (en) | 2019-06-25 | 2020-12-30 | Manus Bio, Inc. | Uridine diphosphate-dependent glycosyltransferase enzyme |
| CN110699373B (zh) * | 2019-10-16 | 2023-05-26 | 中国药科大学 | 尿苷二磷酸葡萄糖高产菌株及其应用 |
| CN111518825B (zh) * | 2020-04-30 | 2022-10-11 | 浙江工业大学 | 一种多基因组合表达制备蛹虫草多糖的方法 |
| US20230174993A1 (en) * | 2020-05-13 | 2023-06-08 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| WO2022002918A1 (en) * | 2020-07-03 | 2022-01-06 | C-Lecta Gmbh | One-pot cell-free glycosylation process |
| CA3200689A1 (en) * | 2020-11-24 | 2022-06-02 | Manus Bio Inc. | Glycoside product biosynthesis and recovery |
| US20250320470A1 (en) * | 2020-12-23 | 2025-10-16 | Samyang Corporation | Glycosyltransferase and steviol glucoside preparation method using same |
| JP7720917B2 (ja) * | 2021-01-27 | 2025-08-08 | コリア アドバンスト インスティテュート オブ サイエンス アンド テクノロジー | Ｃ－グリコシルトランスフェラーゼ変異体およびその用途 |
| WO2023000243A1 (zh) * | 2021-07-22 | 2023-01-26 | 深圳先进技术研究院 | 重组酵母生物转化生产葡萄糖的方法 |
| WO2023121426A1 (ko) * | 2021-12-24 | 2023-06-29 | 주식회사 삼양사 | 레바우디오사이드의 생산 |
| CN114540396A (zh) * | 2022-02-24 | 2022-05-27 | 天津大学 | 希瓦氏菌株中葡萄糖代谢通路的构建方法 |
| CN114561310B (zh) * | 2022-03-17 | 2022-12-02 | 江南大学 | 一种生产甜茶苷的酿酒酵母及其应用 |
| WO2024121721A1 (en) * | 2022-12-05 | 2024-06-13 | Tate & Lyle Solutions Usa Llc | Methods for obtaining steviol glycosides |
| WO2024146325A1 (zh) * | 2023-01-06 | 2024-07-11 | 中国人民解放军军事科学院军事医学研究院 | 用于生产抗原多糖-载体蛋白生物偶联产物的工程菌及其应用 |
| CN115975902B (zh) * | 2023-01-31 | 2025-07-01 | 深圳中科欣扬生物科技有限公司 | 一种全细胞催化合成阿魏酸葡萄糖苷的基因工程菌及其应用 |
| CN118240855A (zh) * | 2024-03-22 | 2024-06-25 | 百开盛(上海)生物科技有限公司 | Udpg生产菌株及其构建方法和应用 |
| CN118374427B (zh) * | 2024-05-07 | 2025-01-24 | 山东三元生物科技股份有限公司 | 一株催化甜菊糖粗糖生成莱鲍迪甙d的重组菌及其应用 |
| WO2025238040A1 (en) * | 2024-05-16 | 2025-11-20 | Evonik Operations Gmbh | A novel glucolipid |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6586214B1 (en) * | 1999-09-15 | 2003-07-01 | Degussa Ag | Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene) |
| CN105671108A (zh) * | 2010-06-02 | 2016-06-15 | 沃维公司 | 甜菊糖苷的重组生产 |
| CN108396044A (zh) * | 2011-08-08 | 2018-08-14 | 埃沃尔瓦公司 | 甜菊醇糖苷类的重组生产 |
| BR112014028819A2 (pt) * | 2012-05-22 | 2017-07-25 | Purecircle Sdn Bhd | glicosídeos de esteviol de pureza elevada |
| CN103397064B (zh) * | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
| EP3215629B1 (en) | 2014-11-05 | 2024-08-07 | Manus Bio Inc. | Microbial production of steviol glycosides |
| US20180057850A1 (en) * | 2015-03-23 | 2018-03-01 | Dsm Ip Assets B.V. | Udp-glycosyltransferases from solanum lycopersicum |
| KR101669041B1 (ko) * | 2015-03-31 | 2016-10-25 | 아주대학교산학협력단 | 스테비오사이드 생산능을 가지는 재조합 미생물 및 이를 이용한 스테비오사이드의 생산 방법 |
| US20190169664A1 (en) | 2016-05-06 | 2019-06-06 | University Of Georgia Research Foundation, Inc. | Microbial platform for production of glycosylated compounds |
| CA3175070A1 (en) * | 2017-02-03 | 2018-08-09 | Codexis, Inc. | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
| AU2019304965B2 (en) * | 2018-07-16 | 2025-04-24 | Manus Bio, Inc. | Production of steviol glycosides through whole cell biotransformation |
| WO2020264179A1 (en) * | 2019-06-25 | 2020-12-30 | Manus Bio, Inc. | Uridine diphosphate-dependent glycosyltransferase enzyme |
-
2019
- 2019-07-16 AU AU2019304965A patent/AU2019304965B2/en active Active
- 2019-07-16 SG SG11202100450TA patent/SG11202100450TA/en unknown
- 2019-07-16 ES ES19837740T patent/ES3013059T3/es active Active
- 2019-07-16 CN CN201980057392.6A patent/CN112867799B/zh active Active
- 2019-07-16 BR BR112021000876-4A patent/BR112021000876A2/pt unknown
- 2019-07-16 MX MX2021000605A patent/MX2021000605A/es unknown
- 2019-07-16 MY MYPI2021000233A patent/MY204735A/en unknown
- 2019-07-16 EP EP19837740.0A patent/EP3824093B1/en active Active
- 2019-07-16 EP EP24213834.5A patent/EP4509609A3/en active Pending
- 2019-07-16 US US16/512,874 patent/US11230724B2/en active Active
- 2019-07-16 WO PCT/US2019/041957 patent/WO2020018506A2/en not_active Ceased
- 2019-07-16 JP JP2021501337A patent/JP7305087B2/ja active Active
- 2019-07-16 KR KR1020217004366A patent/KR102532079B1/ko active Active
- 2019-07-16 CA CA3106633A patent/CA3106633A1/en active Pending
-
2021
- 2021-01-13 IL IL280151A patent/IL280151A/en unknown
- 2021-12-09 US US17/546,758 patent/US12012626B2/en active Active
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