JP2021528391A5 - - Google Patents

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Publication number
JP2021528391A5
JP2021528391A5 JP2020569049A JP2020569049A JP2021528391A5 JP 2021528391 A5 JP2021528391 A5 JP 2021528391A5 JP 2020569049 A JP2020569049 A JP 2020569049A JP 2020569049 A JP2020569049 A JP 2020569049A JP 2021528391 A5 JP2021528391 A5 JP 2021528391A5
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JP
Japan
Prior art keywords
compound
forms
compound according
formula
following
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020569049A
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English (en)
Japanese (ja)
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JP2021528391A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/055005 external-priority patent/WO2019239387A1/en
Publication of JP2021528391A publication Critical patent/JP2021528391A/ja
Publication of JP2021528391A5 publication Critical patent/JP2021528391A5/ja
Pending legal-status Critical Current

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JP2020569049A 2018-06-15 2019-06-14 Ｊａｋファミリーのキナーゼの低分子阻害物質 Pending JP2021528391A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862685737P 2018-06-15 2018-06-15
US62/685,737 2018-06-15
US201962846290P 2019-05-10 2019-05-10
US62/846,290 2019-05-10
PCT/IB2019/055005 WO2019239387A1 (en) 2018-06-15 2019-06-14 Small molecule inhibitors of the jak family of kinases

Publications (2)

Publication Number Publication Date
JP2021528391A JP2021528391A (ja) 2021-10-21
JP2021528391A5 true JP2021528391A5 (enExample) 2022-04-11

Family

ID=67766195

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020569049A Pending JP2021528391A (ja) 2018-06-15 2019-06-14 Ｊａｋファミリーのキナーゼの低分子阻害物質

Country Status (23)

Country Link
US (3) US20200017498A1 (enExample)
EP (1) EP3807277A1 (enExample)
JP (1) JP2021528391A (enExample)
KR (1) KR102768284B1 (enExample)
CN (1) CN112313233A (enExample)
AU (1) AU2019286641A1 (enExample)
BR (1) BR112020024744A2 (enExample)
CA (1) CA3101438A1 (enExample)
CL (1) CL2020003227A1 (enExample)
CO (1) CO2020015396A2 (enExample)
CR (1) CR20200603A (enExample)
EC (1) ECSP20080817A (enExample)
IL (1) IL279314A (enExample)
JO (1) JOP20200311A1 (enExample)
MA (1) MA52900A (enExample)
MX (1) MX2020013688A (enExample)
NI (1) NI202000100A (enExample)
PE (1) PE20212113A1 (enExample)
PH (1) PH12020551984A1 (enExample)
SG (1) SG11202011691PA (enExample)
TW (1) TW202016110A (enExample)
UY (1) UY38262A (enExample)
WO (1) WO2019239387A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190144A1 (ar) 2016-12-16 2019-06-16 Janssen Pharmaceutica Nv إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز
JP7291077B2 (ja) 2016-12-16 2023-06-14 ヤンセン ファーマシューティカ エヌ．ベー． Ｊａｋファミリーのキナーゼの低分子阻害物質
TW202016110A (zh) 2018-06-15 2020-05-01 比利時商健生藥品公司 Ｊａｋ激酶家族之小分子抑制劑
MX2023010642A (es) 2021-03-11 2023-11-28 Janssen Pharmaceutica Nv Lorpucitinib para uso en el tratamiento de trastornos mediados por jak.
CN113292561A (zh) * 2021-05-22 2021-08-24 中国药科大学 一种二吡咯并吡啶结构的化合物、制备方法和医药用途

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UA67844C2 (uk) 1999-04-23 2004-07-15 Смітклайн Бічам Плс Поліморф 5-[4-[2-(n-метил-n-(2-піридил)аміно)етокси]бензил]тіазолідин-2,4-діону солі малеїнової кислоти
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
JP2005529933A (ja) 2002-05-31 2005-10-06 シェーリング　コーポレイション キサンチンホスホジエステラーゼｖインヒビター多形体
GB0319935D0 (en) 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
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AU2006266045A1 (en) 2005-07-01 2007-01-11 Wyeth Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarb-onitrile and methods of preparing the same
WO2007007919A2 (en) 2005-07-14 2007-01-18 Astellas Pharma Inc. Heterocyclic janus kinase 3 inhibitors
CN102127078A (zh) 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
CN104592231A (zh) 2008-06-10 2015-05-06 Abbvie公司 新的三环化合物
MX2012002480A (es) 2009-09-03 2012-03-26 Bristol Myers Squibb Co Inhibidores de jak2 y su uso en el tratamiento de enfermedades mieloproliferativas y cancer.
RU2711869C3 (ru) 2009-12-01 2022-02-02 Эббви Инк. Имидазопирролопиразиновые производные, полезные для лечения заболеваний, вызванных аномальной активностью протеинкиназ Jak1, Jak3 или Syk
PH12012501000A1 (en) * 2009-12-01 2013-02-11 Abbvie Inc Novel tricyclic compounds
RU2012132278A (ru) * 2010-01-12 2014-02-20 Ф. Хоффманн-Ля Рош Аг Трициклические гетероциклические соединения, содержащие их композиции и способы их применения
AU2011214254B2 (en) 2010-02-10 2016-06-09 Genon Biotechnologies Oy Dual activity kinase domains and uses thereof
WO2013007765A1 (en) * 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Fused tricyclic compounds for use as inhibitors of janus kinases
GB201212081D0 (en) 2012-07-06 2012-08-22 Kalvista Pharmaceuticals Ltd New polymorph
JP6248948B2 (ja) 2013-02-08 2017-12-20 日産化学工業株式会社 ３環性ピロロピリジン化合物及びｊａｋ阻害剤
EP2924026A1 (en) 2014-03-28 2015-09-30 Novartis Tiergesundheit AG Aminosulfonylmethylcyclohexanes as JAK inhibitors
BR112016023299A8 (pt) 2014-05-14 2021-06-29 Nissan Chemical Ind Ltd composto tricíclico e inibidor de jak, agente preventivo, terapêutico ou de melhoria para doenças contra as quais inibição de jak é eficaz e para artrite reumatoide, medicamento e utilização desses compostos
ES2753159T3 (es) 2015-05-28 2020-04-07 Theravance Biopharma R&D Ip Llc Compuestos de naftiridina como inhibidores de quinasa JAK
EP3371332A4 (en) 2015-11-04 2019-04-03 Mayo Foundation for Medical Education and Research METHOD AND MATERIALS FOR TREATING AUTOIMMUNE DISEASES
JOP20190053A1 (ar) 2016-09-23 2019-03-21 Novartis Ag مركبات أزا إندازول للاستخدام في إصابات الأوتار و/ أو الرباط
EP3640251B1 (en) 2016-10-24 2021-12-08 Astrazeneca AB 6,7,8,9-tetrahydro-3h-pyrazolo[4,3-f]isoquinoline derivatives useful in the treatment of cancer
JOP20190144A1 (ar) * 2016-12-16 2019-06-16 Janssen Pharmaceutica Nv إيميدازو بيرولو بيريدين كمثبطات لعائلة jak الخاصة بإنزيمات الكيناز
KR102314286B1 (ko) 2016-12-16 2021-10-21 화이자 인코포레이티드 Glp-1 수용체 작용제 및 이의 용도
ES2941631T3 (es) 2016-12-16 2023-05-24 Lilly Co Eli Compuestos de Pirido[4,3-d][1,3]oxazin-2-ona como inhibidores de IDH1 e IDH2 mutantes
JP7291077B2 (ja) * 2016-12-16 2023-06-14 ヤンセン ファーマシューティカ エヌ．ベー． Ｊａｋファミリーのキナーゼの低分子阻害物質
EP3555050A1 (en) 2016-12-16 2019-10-23 Basf Se Pesticidal compounds
WO2018109074A1 (en) 2016-12-16 2018-06-21 Nestec Sa Oligosaccharides for flavour generation
LT3568396T (lt) 2017-01-11 2021-02-10 Leo Pharma A/S Nauji amino-imidazopiridino dariniai, kaip janus kinazės inhibitoriai ir jų farmacinis panaudojimas
PL3494116T3 (pl) 2017-01-30 2020-04-30 Astrazeneca Ab Modulatory receptora estrogenowego
MX2019012431A (es) 2017-04-21 2020-08-03 Ikena Oncology Inc Inhibidores del receptor de hidrocarburos de arilo (ahr) de indol y usos de los mismos.
TW202016110A (zh) 2018-06-15 2020-05-01 比利時商健生藥品公司 Ｊａｋ激酶家族之小分子抑制劑
WO2020216936A1 (en) 2019-04-24 2020-10-29 Janssen Pharmaceutica Nv Non-clinical liquid formulations of pan-jak inhibitor

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