SG11202011691PA - Small molecule inhibitors of the jak family of kinases - Google Patents
Small molecule inhibitors of the jak family of kinasesInfo
- Publication number
- SG11202011691PA SG11202011691PA SG11202011691PA SG11202011691PA SG11202011691PA SG 11202011691P A SG11202011691P A SG 11202011691PA SG 11202011691P A SG11202011691P A SG 11202011691PA SG 11202011691P A SG11202011691P A SG 11202011691PA SG 11202011691P A SG11202011691P A SG 11202011691PA
- Authority
- SG
- Singapore
- Prior art keywords
- kinases
- small molecule
- molecule inhibitors
- jak family
- jak
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862685737P | 2018-06-15 | 2018-06-15 | |
| US201962846290P | 2019-05-10 | 2019-05-10 | |
| PCT/IB2019/055005 WO2019239387A1 (en) | 2018-06-15 | 2019-06-14 | Small molecule inhibitors of the jak family of kinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202011691PA true SG11202011691PA (en) | 2020-12-30 |
Family
ID=67766195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202011691PA SG11202011691PA (en) | 2018-06-15 | 2019-06-14 | Small molecule inhibitors of the jak family of kinases |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20200017498A1 (en) |
| EP (1) | EP3807277A1 (en) |
| JP (1) | JP2021528391A (en) |
| KR (1) | KR20210021342A (en) |
| CN (1) | CN112313233A (en) |
| AU (1) | AU2019286641A1 (en) |
| BR (1) | BR112020024744A2 (en) |
| CA (1) | CA3101438A1 (en) |
| CL (1) | CL2020003227A1 (en) |
| CO (1) | CO2020015396A2 (en) |
| CR (1) | CR20200603A (en) |
| EC (1) | ECSP20080817A (en) |
| IL (1) | IL279314A (en) |
| JO (1) | JOP20200311A1 (en) |
| MA (1) | MA52900A (en) |
| MX (1) | MX2020013688A (en) |
| NI (1) | NI202000100A (en) |
| PE (1) | PE20212113A1 (en) |
| PH (1) | PH12020551984A1 (en) |
| SG (1) | SG11202011691PA (en) |
| TW (1) | TW202016110A (en) |
| UY (1) | UY38262A (en) |
| WO (1) | WO2019239387A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190144A1 (en) | 2016-12-16 | 2019-06-16 | Janssen Pharmaceutica Nv | Imidazopyrrolopyridine as inhibitors of the jak family of kinases |
| UA125042C2 (en) | 2016-12-16 | 2021-12-29 | Янссен Фармацевтика Нв | Small molecule inhibitors of the jak family of kinases |
| TW202016110A (en) | 2018-06-15 | 2020-05-01 | 比利時商健生藥品公司 | Small molecule inhibitors of the jak family of kinases |
| US20220288041A1 (en) * | 2021-03-11 | 2022-09-15 | Janssen Pharmaceutica Nv | Small molecule inhibitor of the jak family of kinases |
| CN113292561A (en) * | 2021-05-22 | 2021-08-24 | 中国药科大学 | Compound with dipyrrolopyridine structure, preparation method and medical application |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6080747A (en) | 1999-03-05 | 2000-06-27 | Hughes Institute | JAK-3 inhibitors for treating allergic disorders |
| US6806280B1 (en) | 1999-04-23 | 2004-10-19 | Smithkline Beecham P.L.C. | Polymorph of 5-[4-[2-(n-methyl-n(2-pyridyl)amino)ethoxy]benzyl]-thiazolidine-2,4-dione, maleic acid salt |
| AR033485A1 (en) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | MEDICINAL SUBSTANCE OF ARIPIPRAZOL OF LOW HYGROSCOPICITY AND PROCESS FOR THE PREPARATION OF THE SAME |
| AR040233A1 (en) | 2002-05-31 | 2005-03-23 | Schering Corp | XANTINA FOSFODIESTERASA V INHIBITING POLYMORPHES |
| GB0319935D0 (en) | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
| US7737279B2 (en) | 2005-05-10 | 2010-06-15 | Bristol-Myers Squibb Company | 1,6-dihydro-1,3,5,6-tetraaza-as-indacene based tricyclic compounds and pharmaceutical compositions comprising same |
| JP2009500332A (en) | 2005-07-01 | 2009-01-08 | ワイス | Crystal form of 4-[(2,4-dichloro-5-methoxyphenyl) amino] -6-methoxy-7- [3- (4-methyl-1-piperazinyl) propoxy] -3-quinolinecarbonitrile and its preparation Method |
| WO2007007919A2 (en) | 2005-07-14 | 2007-01-18 | Astellas Pharma Inc. | Heterocyclic janus kinase 3 inhibitors |
| EP2251341A1 (en) | 2005-07-14 | 2010-11-17 | Astellas Pharma Inc. | Heterocyclic Janus kinase 3 inhibitors |
| CA2727032C (en) | 2008-06-10 | 2018-08-14 | Abbott Laboratories | Tricyclic compounds |
| WO2011028864A1 (en) | 2009-09-03 | 2011-03-10 | Bristol-Myers Squibb Company | Jak2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer |
| JP2013512282A (en) | 2009-12-01 | 2013-04-11 | アボット・ラボラトリーズ | New tricyclic compounds |
| RU2570416C9 (en) | 2009-12-01 | 2019-11-25 | Эббви Инк. | Imidazopyrrolopyrazine derivatives, useful for treatment of diseases, caused by abnormal activity of proteinkinases jak1, jak3 or syk |
| BR112012017269A2 (en) | 2010-01-12 | 2016-05-03 | Hoffmann La Roche | tricyclic heterocyclic compounds, compositions and methods of use thereof |
| EP2534258B1 (en) | 2010-02-10 | 2017-09-20 | Genon Biotechnologies OY | Dual activity kinase domains and uses thereof |
| WO2013007765A1 (en) * | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Fused tricyclic compounds for use as inhibitors of janus kinases |
| GB201212081D0 (en) | 2012-07-06 | 2012-08-22 | Kalvista Pharmaceuticals Ltd | New polymorph |
| ES2755130T3 (en) | 2013-02-08 | 2020-04-21 | Nissan Chemical Corp | Tricyclic pyrrolopyridine compound, and JAK inhibitor |
| EP2924026A1 (en) | 2014-03-28 | 2015-09-30 | Novartis Tiergesundheit AG | Aminosulfonylmethylcyclohexanes as JAK inhibitors |
| MX2016014823A (en) | 2014-05-14 | 2017-03-10 | Nissan Chemical Ind Ltd | Tricyclic compound and jak inhibitor. |
| MX2020011774A (en) | 2015-05-28 | 2021-06-01 | Theravance Biopharma R&D Ip Llc | Naphthyridine compounds as jak kinase inhibitors. |
| WO2017079639A1 (en) | 2015-11-04 | 2017-05-11 | Mayo Foundation For Medical Education And Research | Methods and materials for treating autoimmune conditions |
| JOP20190053A1 (en) | 2016-09-23 | 2019-03-21 | Novartis Ag | Aza-indazole compounds for use in tendon and/or ligament injuries |
| HRP20220255T1 (en) | 2016-10-24 | 2022-04-29 | Astrazeneca Ab | 6,7,8,9-tetrahydro-3h-pyrazolo[4,3-f]isoquinoline derivatives useful in the treatment of cancer |
| UA125042C2 (en) * | 2016-12-16 | 2021-12-29 | Янссен Фармацевтика Нв | Small molecule inhibitors of the jak family of kinases |
| RS63849B9 (en) | 2016-12-16 | 2023-06-30 | Pfizer | Glp-1 receptor agonists and uses thereof |
| US20190281874A1 (en) | 2016-12-16 | 2019-09-19 | Nestec S.A. | Oligosaccharides for flavour generation |
| MX2019007120A (en) | 2016-12-16 | 2019-09-16 | Basf Se | Pesticidal compounds. |
| JOP20190144A1 (en) | 2016-12-16 | 2019-06-16 | Janssen Pharmaceutica Nv | Imidazopyrrolopyridine as inhibitors of the jak family of kinases |
| CA3045303C (en) | 2016-12-16 | 2022-05-17 | Eli Lilly And Company | 7-phenylethylamino-4h-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant idh1 and idh2 inhibitors |
| BR112019014191A2 (en) | 2017-01-11 | 2020-02-11 | Leo Pharma A/S | COMPOUND, PHARMACEUTICAL COMPOSITION, AND METHOD FOR PREVENTING, TREATING OR IMPROVING DISEASES OF THE IMMUNE SYSTEM. |
| CN110214140B (en) | 2017-01-30 | 2022-08-30 | 阿斯利康(瑞典)有限公司 | Estrogen receptor modulators |
| AU2018256459B2 (en) | 2017-04-21 | 2023-12-07 | Ikena Oncology, Inc. | Indole AHR inhibitors and uses thereof |
| TW202016110A (en) | 2018-06-15 | 2020-05-01 | 比利時商健生藥品公司 | Small molecule inhibitors of the jak family of kinases |
| US20200338051A1 (en) | 2019-04-24 | 2020-10-29 | Janssen Pharmaceutica Nv | Non-clinical liquid formulations of pan-jak inhibitor |
-
2019
- 2019-06-13 TW TW108120432A patent/TW202016110A/en unknown
- 2019-06-14 CN CN201980040198.7A patent/CN112313233A/en active Pending
- 2019-06-14 UY UY0001038262A patent/UY38262A/en unknown
- 2019-06-14 CA CA3101438A patent/CA3101438A1/en active Pending
- 2019-06-14 SG SG11202011691PA patent/SG11202011691PA/en unknown
- 2019-06-14 AU AU2019286641A patent/AU2019286641A1/en active Pending
- 2019-06-14 PE PE2020001995A patent/PE20212113A1/en unknown
- 2019-06-14 MA MA052900A patent/MA52900A/en unknown
- 2019-06-14 WO PCT/IB2019/055005 patent/WO2019239387A1/en active Application Filing
- 2019-06-14 JO JOP/2020/0311A patent/JOP20200311A1/en unknown
- 2019-06-14 MX MX2020013688A patent/MX2020013688A/en unknown
- 2019-06-14 EP EP19759032.6A patent/EP3807277A1/en active Pending
- 2019-06-14 CR CR20200603A patent/CR20200603A/en unknown
- 2019-06-14 BR BR112020024744-8A patent/BR112020024744A2/en not_active Application Discontinuation
- 2019-06-14 JP JP2020569049A patent/JP2021528391A/en active Pending
- 2019-06-14 KR KR1020217000012A patent/KR20210021342A/en not_active Application Discontinuation
- 2019-09-24 US US16/581,081 patent/US20200017498A1/en not_active Abandoned
-
2020
- 2020-01-29 US US16/776,243 patent/US11066406B2/en active Active
- 2020-11-19 PH PH12020551984A patent/PH12020551984A1/en unknown
- 2020-12-09 IL IL279314A patent/IL279314A/en unknown
- 2020-12-09 CO CONC2020/0015396A patent/CO2020015396A2/en unknown
- 2020-12-11 CL CL2020003227A patent/CL2020003227A1/en unknown
- 2020-12-11 NI NI202000100A patent/NI202000100A/en unknown
- 2020-12-14 EC ECSENADI202080817A patent/ECSP20080817A/en unknown
-
2021
- 2021-07-15 US US17/377,249 patent/US11787807B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CL2020003227A1 (en) | 2021-05-14 |
| ECSP20080817A (en) | 2021-01-29 |
| KR20210021342A (en) | 2021-02-25 |
| US11066406B2 (en) | 2021-07-20 |
| US20200165250A1 (en) | 2020-05-28 |
| MA52900A (en) | 2021-04-21 |
| CN112313233A (en) | 2021-02-02 |
| TW202016110A (en) | 2020-05-01 |
| PE20212113A1 (en) | 2021-11-04 |
| BR112020024744A2 (en) | 2021-03-23 |
| JOP20200311A1 (en) | 2020-11-30 |
| EP3807277A1 (en) | 2021-04-21 |
| MX2020013688A (en) | 2021-02-26 |
| PH12020551984A1 (en) | 2021-08-02 |
| JP2021528391A (en) | 2021-10-21 |
| WO2019239387A1 (en) | 2019-12-19 |
| US20210340144A1 (en) | 2021-11-04 |
| IL279314A (en) | 2021-01-31 |
| US11787807B2 (en) | 2023-10-17 |
| CR20200603A (en) | 2021-01-20 |
| UY38262A (en) | 2019-12-31 |
| NI202000100A (en) | 2021-06-30 |
| US20200017498A1 (en) | 2020-01-16 |
| CA3101438A1 (en) | 2019-12-19 |
| CO2020015396A2 (en) | 2021-03-08 |
| AU2019286641A1 (en) | 2020-12-10 |
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