JP2021526823A5 - - Google Patents

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Publication number
JP2021526823A5
JP2021526823A5 JP2020568694A JP2020568694A JP2021526823A5 JP 2021526823 A5 JP2021526823 A5 JP 2021526823A5 JP 2020568694 A JP2020568694 A JP 2020568694A JP 2020568694 A JP2020568694 A JP 2020568694A JP 2021526823 A5 JP2021526823 A5 JP 2021526823A5
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modified oligonucleotide
modified
compound according
oligomer compound
nucleic acid
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JP2020568694A
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Japanese (ja)
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JP7557378B2 (ja
JPWO2019241648A5 (https=
JP2021526823A (ja
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Priority claimed from PCT/US2019/037215 external-priority patent/WO2019241648A1/en
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Priority to JP2024158702A priority Critical patent/JP2025000690A/ja
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JP2020568694A 2018-06-14 2019-06-14 Ｓｔｍｎ２発現を増加させるための化合物及び方法 Active JP7557378B2 (ja)

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JP2024158702A JP2025000690A (ja) 2018-06-14 2024-09-13 Ｓｔｍｎ２発現を増加させるための化合物及び方法

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US201862685192P 2018-06-14 2018-06-14
US62/685,192 2018-06-14
PCT/US2019/037215 WO2019241648A1 (en) 2018-06-14 2019-06-14 Compounds and methods for increasing stmn2 expression

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JP2021526823A JP2021526823A (ja) 2021-10-11
JP2021526823A5 true JP2021526823A5 (https=) 2022-06-22
JPWO2019241648A5 JPWO2019241648A5 (https=) 2022-06-22
JP7557378B2 JP7557378B2 (ja) 2024-09-27

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JP2024158702A Pending JP2025000690A (ja) 2018-06-14 2024-09-13 Ｓｔｍｎ２発現を増加させるための化合物及び方法

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US (2) US11833168B2 (https=)
EP (1) EP3807411A4 (https=)
JP (2) JP7557378B2 (https=)
AU (1) AU2019287635B2 (https=)
CA (1) CA3103429A1 (https=)
WO (1) WO2019241648A1 (https=)

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EA202091693A1 (ru) 2018-01-12 2021-04-14 Бристол-Маерс Сквибб Компани Антисмысловые олигонуклеотиды, целенаправленно воздействующие на альфа-синуклеин, и их применения
BR112020013994A2 (pt) 2018-01-12 2020-12-08 Bristol-Myers Squibb Company Oligonucleotídeos antissenso que direcionam alfa-sinucleína e seus usos
CA3103429A1 (en) 2018-06-14 2019-12-19 Don W. Cleveland Compounds and methods for increasing stmn2 expression
WO2020150290A2 (en) 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
JP7795914B2 (ja) * 2019-06-03 2026-01-08 クラリス コーポレーション 神経学的疾患を処置するためのオリゴヌクレオチドおよびその使用方法
WO2021076964A1 (en) * 2019-10-17 2021-04-22 Icahn School Of Medicine At Mount Sinai Stathmin 2 (stmn2) as a therapeutic target for parkinson's disease
EP4127172A4 (en) * 2020-03-25 2025-06-04 President and Fellows of Harvard College Methods and compositions for restoring STMN2 levels
EP4162051A4 (en) * 2020-06-03 2025-07-09 Quralis Corp TREATMENT OF NEUROLOGICAL DISEASES USING GENE TRANSCRIPT MODULATORS
CN116528878A (zh) * 2020-06-03 2023-08-01 奎里斯公司 使用基因转录物调控剂治疗神经学疾病
WO2022018187A1 (en) 2020-07-23 2022-01-27 F. Hoffmann-La Roche Ag Oligonucleotides targeting rna binding protein sites
WO2022018155A1 (en) 2020-07-23 2022-01-27 F. Hoffmann-La Roche Ag Lna oligonucleotides for splice modulation of stmn2
PE20250394A1 (es) 2022-05-18 2025-02-11 Hoffmann La Roche Oligonucleotidos mejorados que actuan sobre sitios de proteina de union a arn

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