JP2020528910A5 - - Google Patents
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- JP2020528910A5 JP2020528910A5 JP2020504133A JP2020504133A JP2020528910A5 JP 2020528910 A5 JP2020528910 A5 JP 2020528910A5 JP 2020504133 A JP2020504133 A JP 2020504133A JP 2020504133 A JP2020504133 A JP 2020504133A JP 2020528910 A5 JP2020528910 A5 JP 2020528910A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- aspects
- composition according
- tablets
- series
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762538504P | 2017-07-28 | 2017-07-28 | |
| US62/538,504 | 2017-07-28 | ||
| PCT/US2018/043867 WO2019023439A1 (en) | 2017-07-28 | 2018-07-26 | PROCESS FOR THE PREPARATION OF OLIGONUCLEOTIDE COMPOUNDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020528910A JP2020528910A (ja) | 2020-10-01 |
| JP2020528910A5 true JP2020528910A5 (https=) | 2021-09-09 |
Family
ID=65041406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020504133A Pending JP2020528910A (ja) | 2017-07-28 | 2018-07-26 | オリゴヌクレオチド化合物の調製方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200392491A1 (https=) |
| EP (1) | EP3658155A4 (https=) |
| JP (1) | JP2020528910A (https=) |
| KR (1) | KR20200042902A (https=) |
| CN (1) | CN111148519A (https=) |
| WO (1) | WO2019023439A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3420082A4 (en) | 2016-02-23 | 2019-10-16 | Celgene Alpine Investment Company II, LLC | METHOD FOR THE TREATMENT OF DARM FIBROSIS USING SMAD7 INHIBITION |
| JP7503072B2 (ja) * | 2019-02-26 | 2024-06-19 | ロシュ イノベーション センター コペンハーゲン エーエス | オリゴヌクレオチドの製剤化方法 |
| JP7311642B2 (ja) * | 2019-07-09 | 2023-07-19 | エフ． ホフマン－ラ ロシュ アーゲー | オリゴヌクレオチドを脱保護するための方法 |
| CN110468171B (zh) * | 2019-09-20 | 2021-10-29 | 凯莱英医药集团（天津）股份有限公司 | 核酸的合成方法 |
| JP2023515485A (ja) * | 2020-02-21 | 2023-04-13 | バイオジェン・エムエイ・インコーポレイテッド | 限外濾過／透析濾過を用いたオリゴヌクレオチド組成物の調製方法 |
| WO2024138152A1 (en) * | 2022-12-23 | 2024-06-27 | Asahi Kasei Bioprocess America, Inc. | System for performing cleavage, deprotection, ultrafiltration, and diafiltration operations |
| CN117143165B (zh) * | 2023-08-30 | 2026-02-03 | 上海奥锐特生物科技有限公司 | 一种寡核苷酸的纯化方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007050789A2 (en) * | 2005-10-25 | 2007-05-03 | Nëdken Corporation | Glycosyl-oligonucleotide conjugates and methods |
| DK2951191T3 (en) * | 2013-01-31 | 2019-01-14 | Ionis Pharmaceuticals Inc | PROCEDURE FOR MANUFACTURING OLIGOMERIC COMPOUNDS USING MODIFIED CLUTCH PROTOCOLS |
| AU2015257589A1 (en) * | 2014-05-09 | 2016-11-24 | Nogra Pharma Limited | Methods for treating inflammatory bowel disease |
| EP3207135A2 (en) * | 2014-10-17 | 2017-08-23 | Celgene Alpine Investment Company II, LLC | Isotopologues of smad7 antisense oligonucleotides |
| CA3000569A1 (en) * | 2015-09-30 | 2017-04-06 | Nogra Pharma Limited | Methods of using smad7 antisense oligonucleotides based on biomarker expression |
-
2018
- 2018-07-26 JP JP2020504133A patent/JP2020528910A/ja active Pending
- 2018-07-26 WO PCT/US2018/043867 patent/WO2019023439A1/en not_active Ceased
- 2018-07-26 EP EP18837870.7A patent/EP3658155A4/en not_active Withdrawn
- 2018-07-26 KR KR1020207004894A patent/KR20200042902A/ko not_active Withdrawn
- 2018-07-26 CN CN201880062621.9A patent/CN111148519A/zh active Pending
- 2018-07-26 US US16/634,078 patent/US20200392491A1/en not_active Abandoned
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