JP2021523208A5 - - Google Patents
Info
- Publication number
- JP2021523208A5 JP2021523208A5 JP2020564227A JP2020564227A JP2021523208A5 JP 2021523208 A5 JP2021523208 A5 JP 2021523208A5 JP 2020564227 A JP2020564227 A JP 2020564227A JP 2020564227 A JP2020564227 A JP 2020564227A JP 2021523208 A5 JP2021523208 A5 JP 2021523208A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- item
- succinate
- approximately
- crystalline form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024031206A JP2024051160A (ja) | 2018-05-14 | 2024-03-01 | ピリミジン誘導体の医薬塩及び障害の処置方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862671166P | 2018-05-14 | 2018-05-14 | |
| US201862671182P | 2018-05-14 | 2018-05-14 | |
| US62/671,166 | 2018-05-14 | ||
| US62/671,182 | 2018-05-14 | ||
| PCT/US2019/032002 WO2019222093A1 (en) | 2018-05-14 | 2019-05-13 | Pharmaceutical salts of pyrimidine derivatives and method of treating disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024031206A Division JP2024051160A (ja) | 2018-05-14 | 2024-03-01 | ピリミジン誘導体の医薬塩及び障害の処置方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021523208A JP2021523208A (ja) | 2021-09-02 |
| JP2021523208A5 true JP2021523208A5 (https=) | 2022-05-20 |
Family
ID=68540756
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564227A Pending JP2021523208A (ja) | 2018-05-14 | 2019-05-13 | ピリミジン誘導体の医薬塩及び障害の処置方法 |
| JP2024031206A Pending JP2024051160A (ja) | 2018-05-14 | 2024-03-01 | ピリミジン誘導体の医薬塩及び障害の処置方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024031206A Pending JP2024051160A (ja) | 2018-05-14 | 2024-03-01 | ピリミジン誘導体の医薬塩及び障害の処置方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12084431B2 (https=) |
| EP (2) | EP3793993A4 (https=) |
| JP (2) | JP2021523208A (https=) |
| KR (1) | KR20200144579A (https=) |
| CN (1) | CN112313223A (https=) |
| AU (1) | AU2019269372A1 (https=) |
| BR (1) | BR112020023107A2 (https=) |
| CA (1) | CA3099737A1 (https=) |
| MX (1) | MX2020012063A (https=) |
| TW (1) | TWI831780B (https=) |
| WO (1) | WO2019222093A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3943491T (pt) | 2019-03-19 | 2025-07-28 | Voronoi Inc | Derivado de heteroarilo, método para a produção do mesmo e composição farmacêutica que compreende o mesmo como componente eficaz |
| US12157730B2 (en) | 2019-03-19 | 2024-12-03 | Voronoi Inc. | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
| US20220340547A1 (en) * | 2019-05-22 | 2022-10-27 | Shanghi Hansoh Biosoh Biomedical Co., Ltd. | Indole derivative-containing inhibitor, preparation method therefor and application thereof |
| CN111303125A (zh) * | 2020-04-10 | 2020-06-19 | 天津法莫西医药科技有限公司 | 一种甲氧基取代吲哚-嘧啶类化合物及其制备方法 |
| TW202309022A (zh) | 2021-04-13 | 2023-03-01 | 美商努法倫特公司 | 用於治療具egfr突變之癌症之胺基取代雜環 |
| WO2023277172A1 (en) | 2021-06-30 | 2023-01-05 | Takeda Pharmaceutical Company Limited | Process for preparing pharmaceutical salts of pyrimidine derivatives |
| EP4367116A4 (en) * | 2021-07-07 | 2025-04-30 | Crimson Biopharm Inc. | Crystalline polymorphs of epidermal growth factor receptor inhibition, and compositions and methods therefor |
| JP7734995B2 (ja) * | 2021-08-06 | 2025-09-08 | 上海和誉生物医薬科技有限公司 | ピリミジンまたはピリジン誘導体およびその製造方法ならびに薬学上の応用 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1029958C (zh) | 1986-03-31 | 1995-10-11 | 联合碳化农产化学品公司 | 丙二酸衍生物阻滞植物生长的用途 |
| JP2749578B2 (ja) | 1986-03-31 | 1998-05-13 | ローヌープーラン・ネーデルランド・ベー・ベー | 相乗的植物成長調節剤組成物 |
| EP0261226A1 (en) | 1986-03-31 | 1988-03-30 | Rhone Poulenc Nederland B.V. | Use of malonic acid derivative compounds for increasing crop yield |
| EP1100788B1 (en) * | 1998-07-30 | 2005-11-09 | Wyeth | Substituted quinazoline derivatives |
| EP1248869A2 (en) * | 2000-01-07 | 2002-10-16 | Transform Pharmaceuticals, Inc. | High-throughput formation, identification, and analysis of diverse solid-forms |
| US7019017B2 (en) | 2002-05-14 | 2006-03-28 | Baylor College Of Medicine | Small molecule inhibitors of HER2 expression |
| GB0311274D0 (en) * | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
| EP1778648A2 (en) | 2004-08-19 | 2007-05-02 | ICOS Corporation | Compounds useful for inhibiting chk1 |
| KR20080057296A (ko) | 2005-10-21 | 2008-06-24 | 머크 앤드 캄파니 인코포레이티드 | 칼륨 채널 억제제 |
| PT1948180E (pt) | 2005-11-11 | 2013-05-10 | Boehringer Ingelheim Int | Tratamento de combinação de cancro compreendendo inibidores de egfr/her2 |
| TW200826843A (en) | 2006-09-13 | 2008-07-01 | Sumitomo Chemical Co | Thiadiazole compound and use thereof |
| FR2911138B1 (fr) | 2007-01-05 | 2009-02-20 | Sanofi Aventis Sa | Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk |
| FR2911139A1 (fr) | 2007-01-05 | 2008-07-11 | Sanofi Aventis Sa | Nouveaux derives de phenyl-(4-phenyl-pyrimidin-2-yl)amines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk |
| FR2911140B1 (fr) | 2007-01-05 | 2009-02-20 | Sanofi Aventis Sa | Nouveaux derives de 2-anilino 4-heteroaryle pyrimides, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk |
| PL2171090T3 (pl) | 2007-06-08 | 2013-09-30 | Genentech Inc | Markery ekspresji genów odporności guza na leczenie hamujące HER2 |
| CA2692379A1 (en) | 2007-07-02 | 2009-01-08 | Boehringer Ingelheim International Gmbh | Antiproliferative compounds based on 5-membered heterocycles |
| FR2919869B1 (fr) | 2007-08-09 | 2009-09-25 | Sanofi Aventis Sa | Nouveaux derives de n, n'-2,4-dianilinopyrimidines, leur preparation a titre de medicaments, compositions pharmaceutiques et notamment comme inhibiteurs de ikk |
| NZ603525A (en) | 2008-06-27 | 2015-02-27 | Celgene Avilomics Res Inc | Pyrimidine based compound and uses thereof |
| CN101723936B (zh) | 2008-10-27 | 2014-01-15 | 上海睿星基因技术有限公司 | 激酶抑制剂及其在药学中的用途 |
| WO2010093808A1 (en) | 2009-02-11 | 2010-08-19 | Reaction Biology Corp. | Selective kinase inhibitors |
| UY32582A (es) | 2009-04-28 | 2010-11-30 | Amgen Inc | Inhibidores de fosfoinositida 3 cinasa y/u objetivo mamífero |
| US9908884B2 (en) | 2009-05-05 | 2018-03-06 | Dana-Farber Cancer Institute, Inc. | EGFR inhibitors and methods of treating disorders |
| EP2430013B1 (en) | 2009-05-13 | 2014-10-15 | Amgen Inc. | Heteroaryl compounds as pikk inhibitors |
| WO2011082266A2 (en) | 2009-12-30 | 2011-07-07 | Arqule, Inc. | Substituted heterocyclic compounds |
| WO2012020215A1 (en) | 2010-08-09 | 2012-02-16 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Amino- imidazolothiadiazoles for use as protein or lipid kinase inhibitors |
| US9034884B2 (en) | 2010-11-19 | 2015-05-19 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors |
| PE20140146A1 (es) | 2010-11-19 | 2014-02-06 | Incyte Corp | Derivados de pirrolopiridina y pirrolopirimidina sustituidos con ciclobutilo como inhibidores de jak |
| JP2014513724A (ja) | 2011-05-16 | 2014-06-05 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 融合二環キナーゼ阻害剤 |
| EP4119551A1 (en) | 2011-07-27 | 2023-01-18 | Astrazeneca AB | 2-(2,4,5-substituted-anilino)pyrimidine compounds |
| CN104684906B (zh) | 2012-05-11 | 2017-06-09 | 艾伯维公司 | Nampt抑制剂 |
| AR091023A1 (es) | 2012-05-11 | 2014-12-30 | Abbvie Inc | Inhibidores del nampt |
| EP2968285A4 (en) | 2013-03-13 | 2016-12-21 | Flatley Discovery Lab | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS |
| WO2015039613A1 (zh) | 2013-09-18 | 2015-03-26 | 北京韩美药品有限公司 | 抑制btk和/或jak3激酶活性的化合物 |
| KR101879422B1 (ko) | 2013-09-18 | 2018-07-17 | 베이징 한미 파마슈티컬 컴퍼니 리미티드 | Btk 및/또는 jak3 키나제의 활성을 억제하는 화합물 |
| CN104860941B (zh) | 2014-02-25 | 2017-03-22 | 上海海雁医药科技有限公司 | 2,4‑二取代苯‑1,5‑二胺衍生物及其应用以及由其制备的药物组合物和药用组合物 |
| EP3119763A1 (en) | 2014-03-18 | 2017-01-25 | Iteos Therapeutics | Novel 3-indol substituted derivatives, pharmaceutical compositions and methods for use |
| EP3778584A1 (en) * | 2014-06-19 | 2021-02-17 | ARIAD Pharmaceuticals, Inc. | Production process of 2-chloro-4-heteroaryl-pyrimidine derivatives |
| GB201416754D0 (en) | 2014-09-23 | 2014-11-05 | Mission Therapeutics Ltd | Novel compounds |
| WO2016054987A1 (zh) | 2014-10-11 | 2016-04-14 | 上海翰森生物医药科技有限公司 | Egfr抑制剂及其制备和应用 |
| TWI696617B (zh) | 2015-04-28 | 2020-06-21 | 大陸商上海復尚慧創醫藥研究有限公司 | 特定蛋白質激酶抑制劑 |
| CN106995437A (zh) * | 2016-01-22 | 2017-08-01 | 齐鲁制药有限公司 | 取代吲哚或吲唑嘧啶衍生物及其制备方法和用途 |
| US11026937B2 (en) * | 2016-09-12 | 2021-06-08 | Padlock Therapeutics, Inc. | Heteroaryl inhibitors of PAD4 |
-
2019
- 2019-05-13 JP JP2020564227A patent/JP2021523208A/ja active Pending
- 2019-05-13 KR KR1020207035669A patent/KR20200144579A/ko not_active Ceased
- 2019-05-13 US US17/055,164 patent/US12084431B2/en active Active
- 2019-05-13 WO PCT/US2019/032002 patent/WO2019222093A1/en not_active Ceased
- 2019-05-13 BR BR112020023107-0A patent/BR112020023107A2/pt not_active Application Discontinuation
- 2019-05-13 EP EP19804043.8A patent/EP3793993A4/en not_active Withdrawn
- 2019-05-13 MX MX2020012063A patent/MX2020012063A/es unknown
- 2019-05-13 AU AU2019269372A patent/AU2019269372A1/en not_active Abandoned
- 2019-05-13 CN CN201980042034.8A patent/CN112313223A/zh active Pending
- 2019-05-13 CA CA3099737A patent/CA3099737A1/en active Pending
- 2019-05-13 EP EP23179346.4A patent/EP4234547A3/en not_active Withdrawn
- 2019-05-14 TW TW108116512A patent/TWI831780B/zh not_active IP Right Cessation
-
2024
- 2024-03-01 JP JP2024031206A patent/JP2024051160A/ja active Pending
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