JP2021522800A5 - - Google Patents

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Publication number
JP2021522800A5
JP2021522800A5 JP2020561893A JP2020561893A JP2021522800A5 JP 2021522800 A5 JP2021522800 A5 JP 2021522800A5 JP 2020561893 A JP2020561893 A JP 2020561893A JP 2020561893 A JP2020561893 A JP 2020561893A JP 2021522800 A5 JP2021522800 A5 JP 2021522800A5
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Japan
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pharmaceutical composition
group
oligomer
modified oligonucleotides
modified
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JP2020561893A
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English (en)
Japanese (ja)
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JPWO2019217708A5 (https=
JP2021522800A (ja
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Priority claimed from PCT/US2019/031562 external-priority patent/WO2019217708A1/en
Publication of JP2021522800A publication Critical patent/JP2021522800A/ja
Publication of JP2021522800A5 publication Critical patent/JP2021522800A5/ja
Publication of JPWO2019217708A5 publication Critical patent/JPWO2019217708A5/ja
Pending legal-status Critical Current

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JP2020561893A 2018-05-09 2019-05-09 Atxn3発現を低減するための化合物及び方法 Pending JP2021522800A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862669238P 2018-05-09 2018-05-09
US62/669,238 2018-05-09
PCT/US2019/031562 WO2019217708A1 (en) 2018-05-09 2019-05-09 Compounds and methods for reducing atxn3 expression

Publications (3)

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JP2021522800A JP2021522800A (ja) 2021-09-02
JP2021522800A5 true JP2021522800A5 (https=) 2022-05-13
JPWO2019217708A5 JPWO2019217708A5 (https=) 2022-05-13

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JP2020561893A Pending JP2021522800A (ja) 2018-05-09 2019-05-09 Atxn3発現を低減するための化合物及び方法

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US (3) US11434488B2 (https=)
EP (2) EP4663758A3 (https=)
JP (1) JP2021522800A (https=)
KR (1) KR20210008497A (https=)
CN (1) CN112189053B (https=)
AR (1) AR115375A1 (https=)
AU (1) AU2019266307A1 (https=)
BR (1) BR112020021253A2 (https=)
CA (1) CA3098144A1 (https=)
CL (1) CL2020002888A1 (https=)
CO (1) CO2020013433A2 (https=)
CR (1) CR20200604A (https=)
EA (1) EA202092500A1 (https=)
JO (1) JOP20200283A1 (https=)
MX (1) MX2020011911A (https=)
PE (1) PE20212131A1 (https=)
PH (1) PH12020500668A1 (https=)
SG (1) SG11202010215TA (https=)
TW (1) TW202003541A (https=)
UY (1) UY38225A (https=)
WO (1) WO2019217708A1 (https=)

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JOP20190104A1 (ar) 2016-11-10 2019-05-07 Ionis Pharmaceuticals Inc مركبات وطرق لتقليل التعبير عن atxn3
EA202091693A1 (ru) 2018-01-12 2021-04-14 Бристол-Маерс Сквибб Компани Антисмысловые олигонуклеотиды, целенаправленно воздействующие на альфа-синуклеин, и их применения
BR112020013994A2 (pt) 2018-01-12 2020-12-08 Bristol-Myers Squibb Company Oligonucleotídeos antissenso que direcionam alfa-sinucleína e seus usos
SG11202010215TA (en) 2018-05-09 2020-11-27 Ionis Pharmaceuticals Inc Compounds and methods for reducing atxn3 expression
US20220195431A1 (en) * 2019-02-22 2022-06-23 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing atxn3 expression
EP3980539A1 (en) * 2019-06-06 2022-04-13 F. Hoffmann-La Roche AG Antisense oligonucleotides targeting atxn3
WO2021102373A1 (en) * 2019-11-22 2021-05-27 Alnylam Pharmaceuticals, Inc. Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
CR20220485A (es) * 2020-02-28 2022-11-10 Ionis Pharmaceuticals Inc Compuestos y métodos para modular smn2
JP7776420B2 (ja) * 2020-05-12 2025-11-26 田辺三菱製薬株式会社 Ataxin 3発現を調節するための化合物、方法及び医薬組成物
US20230212572A1 (en) * 2020-06-09 2023-07-06 Roche Innovation Center Copenhagen A/S Guanosine Analogues for Use in Therapeutics Polynucleotides
TW202237842A (zh) 2020-12-03 2022-10-01 瑞士商赫孚孟拉羅股份公司 靶向atxn3之反義寡核苷酸
WO2022117747A2 (en) 2020-12-03 2022-06-09 F. Hoffmann-La Roche Ag Antisense oligonucleotides targeting atxn3
WO2025252669A1 (en) 2024-06-03 2025-12-11 Evotec International Gmbh Modified oligonucleotides for reducing atxn3 expression

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