JP2021515572A5 - - Google Patents
Info
- Publication number
- JP2021515572A5 JP2021515572A5 JP2020548674A JP2020548674A JP2021515572A5 JP 2021515572 A5 JP2021515572 A5 JP 2021515572A5 JP 2020548674 A JP2020548674 A JP 2020548674A JP 2020548674 A JP2020548674 A JP 2020548674A JP 2021515572 A5 JP2021515572 A5 JP 2021515572A5
- Authority
- JP
- Japan
- Prior art keywords
- aavrh74
- modified
- recombinant
- cells
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023104920A JP2023115149A (ja) | 2018-03-16 | 2023-06-27 | キャプシド改変による組織特異的遺伝子送達の増加 |
| JP2024117744A JP2024144521A (ja) | 2018-03-16 | 2024-07-23 | キャプシド改変による組織特異的遺伝子送達の増加 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862644317P | 2018-03-16 | 2018-03-16 | |
| US62/644,317 | 2018-03-16 | ||
| PCT/US2019/022353 WO2019178412A1 (en) | 2018-03-16 | 2019-03-14 | Increasing tissue specific gene delivery by capsid modification |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023104920A Division JP2023115149A (ja) | 2018-03-16 | 2023-06-27 | キャプシド改変による組織特異的遺伝子送達の増加 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021515572A JP2021515572A (ja) | 2021-06-24 |
| JP2021515572A5 true JP2021515572A5 (https=) | 2022-03-03 |
| JP7304878B2 JP7304878B2 (ja) | 2023-07-07 |
Family
ID=67906893
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020548674A Active JP7304878B2 (ja) | 2018-03-16 | 2019-03-14 | キャプシド改変による組織特異的遺伝子送達の増加 |
| JP2023104920A Pending JP2023115149A (ja) | 2018-03-16 | 2023-06-27 | キャプシド改変による組織特異的遺伝子送達の増加 |
| JP2024117744A Pending JP2024144521A (ja) | 2018-03-16 | 2024-07-23 | キャプシド改変による組織特異的遺伝子送達の増加 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023104920A Pending JP2023115149A (ja) | 2018-03-16 | 2023-06-27 | キャプシド改変による組織特異的遺伝子送達の増加 |
| JP2024117744A Pending JP2024144521A (ja) | 2018-03-16 | 2024-07-23 | キャプシド改変による組織特異的遺伝子送達の増加 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12385062B2 (https=) |
| EP (1) | EP3765624A4 (https=) |
| JP (3) | JP7304878B2 (https=) |
| KR (3) | KR20250111395A (https=) |
| CN (2) | CN111819286B (https=) |
| AU (2) | AU2019234918C1 (https=) |
| BR (1) | BR112020018354A2 (https=) |
| CA (3) | CA3293599A1 (https=) |
| IL (2) | IL317905A (https=) |
| SG (1) | SG11202008687XA (https=) |
| WO (1) | WO2019178412A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2865487T3 (es) | 2015-09-28 | 2021-10-15 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores virales que evaden los anticuerpos |
| EP3765624A4 (en) * | 2018-03-16 | 2022-05-25 | Research Institute at Nationwide Children's Hospital | Increasing tissue specific gene delivery by capsid modification |
| EP3774852A1 (en) | 2018-04-03 | 2021-02-17 | Stridebio, Inc. | Antibody-evading virus vectors |
| MX2020010465A (es) | 2018-04-03 | 2021-01-08 | Vectores de virus para direccionamiento a tejidos oftalmicos. | |
| AU2019247748A1 (en) | 2018-04-03 | 2020-10-08 | Ginkgo Bioworks, Inc. | Antibody-evading virus vectors |
| AR118465A1 (es) | 2019-03-21 | 2021-10-06 | Stridebio Inc | Vectores de virus adenoasociados recombinantes |
| US12611436B2 (en) | 2019-10-17 | 2026-04-28 | Sarepta Therapeutics, Inc. | AAV transfer cassette |
| JP2022551739A (ja) | 2019-10-17 | 2022-12-13 | ストライドバイオ,インコーポレイテッド | ニーマン・ピック病c型の治療のためのアデノ随伴ウイルスベクター |
| AU2021328475A1 (en) | 2020-08-19 | 2023-03-16 | Sarepta Therapeutics, Inc. | Adeno-associated virus vectors for treatment of Rett syndrome |
| US20240299586A1 (en) * | 2021-05-06 | 2024-09-12 | The Regents Of The University Of California | Novel aav serotypes derived from a library screen |
| WO2023196862A1 (en) | 2022-04-06 | 2023-10-12 | Genzyme Corporation | Targeted gene therapy for dm-1 myotonic dystrophy |
| US20240384271A1 (en) * | 2023-04-05 | 2024-11-21 | Genzyme Corporation | Targeted gene therapy for dm-1 myotonic dystrophy |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| EP2345731B1 (en) * | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| WO2012109570A1 (en) | 2011-02-10 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| NZ701693A (en) * | 2012-04-18 | 2017-02-24 | The Children’S Hospital Of Philadelphia | Composition and methods for highly efficient gene transfer using aav capsid variants |
| IL297919A (en) * | 2013-07-22 | 2023-01-01 | Childrens Hospital Philadelphia | Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| CN107073051B (zh) * | 2014-10-21 | 2021-08-24 | 马萨诸塞大学 | 重组aav变体及其用途 |
| ES2865487T3 (es) * | 2015-09-28 | 2021-10-15 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores virales que evaden los anticuerpos |
| ES2977730T3 (es) * | 2016-04-15 | 2024-08-29 | Res Inst Nationwide Childrens Hospital | Administración de microARN-29 y micro-distrofina por virus adenoasociado para tratar la distrofia muscular |
| US11364308B2 (en) * | 2016-05-13 | 2022-06-21 | 4D Molecular Therapeutics Inc. | Adeno-associated virus variant capsids and methods of use thereof |
| EP3765624A4 (en) * | 2018-03-16 | 2022-05-25 | Research Institute at Nationwide Children's Hospital | Increasing tissue specific gene delivery by capsid modification |
| BR112021003174A2 (pt) * | 2018-08-30 | 2021-05-11 | Research Institute At Nationwide Children's Hospital | terapia gênica para o tratamento de galactosemia |
-
2019
- 2019-03-14 EP EP19768552.2A patent/EP3765624A4/en active Pending
- 2019-03-14 US US16/980,821 patent/US12385062B2/en active Active
- 2019-03-14 CA CA3293599A patent/CA3293599A1/en active Pending
- 2019-03-14 KR KR1020257023347A patent/KR20250111395A/ko active Pending
- 2019-03-14 JP JP2020548674A patent/JP7304878B2/ja active Active
- 2019-03-14 CA CA3293598A patent/CA3293598A1/en active Pending
- 2019-03-14 WO PCT/US2019/022353 patent/WO2019178412A1/en not_active Ceased
- 2019-03-14 KR KR1020257023337A patent/KR20250111393A/ko active Pending
- 2019-03-14 CA CA3092353A patent/CA3092353A1/en active Pending
- 2019-03-14 IL IL317905A patent/IL317905A/en unknown
- 2019-03-14 BR BR112020018354-7A patent/BR112020018354A2/pt unknown
- 2019-03-14 CN CN201980018151.0A patent/CN111819286B/zh active Active
- 2019-03-14 CN CN202410503648.4A patent/CN118373887A/zh active Pending
- 2019-03-14 SG SG11202008687XA patent/SG11202008687XA/en unknown
- 2019-03-14 IL IL277270A patent/IL277270B2/en unknown
- 2019-03-14 KR KR1020207028750A patent/KR102834868B1/ko active Active
- 2019-03-14 AU AU2019234918A patent/AU2019234918C1/en active Active
-
2023
- 2023-06-27 JP JP2023104920A patent/JP2023115149A/ja active Pending
-
2024
- 2024-07-23 JP JP2024117744A patent/JP2024144521A/ja active Pending
-
2025
- 2025-06-09 AU AU2025204275A patent/AU2025204275A1/en active Pending
- 2025-07-23 US US19/277,998 patent/US20250346924A1/en active Pending
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