JP2021511374A5 - - Google Patents
Info
- Publication number
- JP2021511374A5 JP2021511374A5 JP2020560532A JP2020560532A JP2021511374A5 JP 2021511374 A5 JP2021511374 A5 JP 2021511374A5 JP 2020560532 A JP2020560532 A JP 2020560532A JP 2020560532 A JP2020560532 A JP 2020560532A JP 2021511374 A5 JP2021511374 A5 JP 2021511374A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- hydrocarbon
- heterocyclic
- stereoisomer
- solvate
- Prior art date
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810044308.4A CN110041327B (zh) | 2018-01-17 | 2018-01-17 | 吡啶酮衍生物、其组合物及作为抗流感病毒药物的应用 |
| CN201810044308.4 | 2018-01-17 | ||
| CN201811517425.4 | 2018-12-12 | ||
| CN201811517425.4A CN111303147B (zh) | 2018-12-12 | 2018-12-12 | 吡啶酮衍生物、其组合物及作为抗流感病毒药物的应用 |
| PCT/CN2019/071902 WO2019141179A1 (zh) | 2018-01-17 | 2019-01-16 | 吡啶酮衍生物、其组合物及作为抗流感病毒药物的应用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021511374A JP2021511374A (ja) | 2021-05-06 |
| JPWO2019141179A5 JPWO2019141179A5 (https=) | 2022-03-15 |
| JP2021511374A5 true JP2021511374A5 (https=) | 2022-03-15 |
| JP7352297B2 JP7352297B2 (ja) | 2023-09-28 |
Family
ID=67301986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560532A Active JP7352297B2 (ja) | 2018-01-17 | 2019-01-16 | ピリドン誘導体と、その組成物、並びにそれらが抗ウイルス薬物としての応用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11247993B2 (https=) |
| EP (1) | EP3753936B1 (https=) |
| JP (1) | JP7352297B2 (https=) |
| KR (1) | KR102477187B1 (https=) |
| CN (4) | CN111848615B (https=) |
| AU (1) | AU2019210414B2 (https=) |
| CA (1) | CA3088926A1 (https=) |
| PH (1) | PH12020551264A1 (https=) |
| SG (1) | SG11202011447UA (https=) |
| WO (1) | WO2019141179A1 (https=) |
| ZA (1) | ZA202007143B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2881776T3 (es) | 2016-03-08 | 2021-11-30 | Novartis Ag | Compuestos tricíclicos útiles para tratar las infecciones por ortomixovirus |
| JOP20170169A1 (ar) | 2016-08-29 | 2019-01-30 | Novartis Ag | مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو |
| JP6924839B2 (ja) | 2017-10-06 | 2021-08-25 | 塩野義製薬株式会社 | 置換された多環性ピリドン誘導体の立体選択的な製造方法 |
| KR20230031990A (ko) | 2018-02-28 | 2023-03-07 | 노파르티스 아게 | 인플루엔자의 치료를 위한 오르토믹소바이러스 복제의 억제제로서의 10-(디(페닐)메틸)-4-히드록시-8,9,9a,10-테트라히드로-7h-피롤로[1',2':4,5]피라지노[1,2-b]피리다진-3,5-디온 유도체 및 관련 화합물 |
| WO2020205835A1 (en) * | 2019-04-01 | 2020-10-08 | Nikang Therapeutics, Inc. | Fused polycyclic pyridone compounds as influenza virus replication inhibitors |
| CN111909174B (zh) | 2019-05-08 | 2022-01-21 | 江西彩石医药科技有限公司 | 吡啶酮衍生物的晶型及制备方法和应用 |
| CN112574170A (zh) * | 2019-09-29 | 2021-03-30 | 江西东邦药业有限公司 | 一种二苯并七元环衍生物及其制备方法和应用 |
| CN118480041A (zh) * | 2019-12-23 | 2024-08-13 | 石家庄迪斯凯威医药科技有限公司 | 取代的多环化合物及其药物组合物和用途 |
| CN113045589B (zh) * | 2019-12-27 | 2024-08-23 | 广东东阳光药业股份有限公司 | 流感病毒复制抑制剂及其用途 |
| CN112898346B (zh) * | 2020-01-23 | 2023-11-10 | 南京知和医药科技有限公司 | 水溶性多环化合物及其药物组合物和用途 |
| CN113116899B (zh) * | 2020-03-06 | 2022-12-20 | 广东众生睿创生物科技有限公司 | 一种用于治疗流感的药物组合物及含有该药物组合物的制剂 |
| CN111943879A (zh) * | 2020-08-03 | 2020-11-17 | 南通大学 | 一种（3s，4r）3-氨基-4（甲氧基甲基）吡咯烷-1-甲酸叔丁酯及其合成方法 |
| CN120289488A (zh) * | 2020-08-11 | 2025-07-11 | 石家庄迪斯凯威医药科技有限公司 | 多环化合物及其药物组合物和用途 |
| WO2022247759A1 (zh) * | 2021-05-22 | 2022-12-01 | 江西彩石医药科技有限公司 | 吡啶酮衍生物的中间体及其制备方法 |
| WO2024074080A1 (zh) * | 2022-10-08 | 2024-04-11 | 石家庄迪斯凯威医药科技有限公司 | 一种抗流感病毒衍生物及其用途 |
| CN117924325A (zh) * | 2022-11-09 | 2024-04-26 | 石家庄迪斯凯威医药科技有限公司 | 一种抗流感病毒衍生物及其用途 |
| CN116789556A (zh) * | 2023-05-26 | 2023-09-22 | 康化（上海）新药研发有限公司 | 一种含环丙氧基乙胺的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2444400T (lt) | 2009-06-15 | 2018-06-11 | Shionogi & Co., Ltd. | Pakeistasis policiklinis karbamoilpiridono darinys |
| MX2013003139A (es) | 2010-09-24 | 2013-06-18 | Shionogi & Co | Profarmaco de derivado de carbamoilpiridona policiclica substituida. |
| WO2015038655A1 (en) * | 2013-09-12 | 2015-03-19 | Alios Biopharma, Inc. | Aza-pyridone compounds and uses thereof |
| MX394421B (es) * | 2015-04-28 | 2025-03-24 | Shionogi & Co | Derivados de piridona policiclica sustituida y profarmaco de los mismos |
| BR112017022550B1 (pt) * | 2015-04-28 | 2021-02-23 | Shionogi & Co., Ltd | derivados policíclicos de piridona substituída |
| AU2016374416A1 (en) | 2015-12-15 | 2018-06-14 | Shionogi & Co., Ltd. | Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug |
| JP6806413B2 (ja) * | 2016-02-03 | 2021-01-06 | 塩野義製薬株式会社 | 多環性ピリドン誘導体およびそのプロドラッグ |
| RU2727962C1 (ru) | 2016-08-10 | 2020-07-28 | Сионоги Энд Ко., Лтд. | Фармацевтические композиции, содержащие замещенные полициклические пиридоновые производные и их пролекарство |
| JOP20170169A1 (ar) | 2016-08-29 | 2019-01-30 | Novartis Ag | مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو |
-
2019
- 2019-01-16 CN CN202010817434.6A patent/CN111848615B/zh active Active
- 2019-01-16 CN CN202010817435.0A patent/CN111848616B/zh active Active
- 2019-01-16 EP EP19741336.2A patent/EP3753936B1/en active Active
- 2019-01-16 SG SG11202011447UA patent/SG11202011447UA/en unknown
- 2019-01-16 US US16/487,088 patent/US11247993B2/en active Active
- 2019-01-16 KR KR1020207023803A patent/KR102477187B1/ko active Active
- 2019-01-16 JP JP2020560532A patent/JP7352297B2/ja active Active
- 2019-01-16 CN CN202010817035.XA patent/CN111848614B/zh active Active
- 2019-01-16 CN CN201980000078.4A patent/CN110637016B/zh active Active
- 2019-01-16 CA CA3088926A patent/CA3088926A1/en active Pending
- 2019-01-16 WO PCT/CN2019/071902 patent/WO2019141179A1/zh not_active Ceased
- 2019-01-16 AU AU2019210414A patent/AU2019210414B2/en active Active
-
2020
- 2020-08-17 PH PH12020551264A patent/PH12020551264A1/en unknown
- 2020-11-16 ZA ZA2020/07143A patent/ZA202007143B/en unknown
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