JP2021510716A5 - - Google Patents

Info

Publication number
JP2021510716A5
JP2021510716A5 JP2020539253A JP2020539253A JP2021510716A5 JP 2021510716 A5 JP2021510716 A5 JP 2021510716A5 JP 2020539253 A JP2020539253 A JP 2020539253A JP 2020539253 A JP2020539253 A JP 2020539253A JP 2021510716 A5 JP2021510716 A5 JP 2021510716A5
Authority
JP
Japan
Prior art keywords
group
protecting group
nucleoside
phosphoramidite
different
Prior art date
Application number
JP2020539253A
Other languages
English (en)
Japanese (ja)
Other versions
JP7493452B2 (ja
JP2021510716A (ja
JPWO2019145713A5 (https=
Filing date
Publication date
Priority claimed from GBGB1801182.5A external-priority patent/GB201801182D0/en
Application filed filed Critical
Publication of JP2021510716A publication Critical patent/JP2021510716A/ja
Publication of JP2021510716A5 publication Critical patent/JP2021510716A5/ja
Publication of JPWO2019145713A5 publication Critical patent/JPWO2019145713A5/ja
Priority to JP2023198864A priority Critical patent/JP2024023388A/ja
Application granted granted Critical
Publication of JP7493452B2 publication Critical patent/JP7493452B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020539253A 2018-01-24 2019-01-23 オリゴヌクレオチド及び核酸の合成 Active JP7493452B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023198864A JP2024023388A (ja) 2018-01-24 2023-11-24 オリゴヌクレオチド及び核酸の合成

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1801182.5A GB201801182D0 (en) 2018-01-24 2018-01-24 Oligonucleotide and nucleic acid synthesis
GB1801182.5 2018-01-24
PCT/GB2019/050192 WO2019145713A1 (en) 2018-01-24 2019-01-23 Oligonucleotide and nucleic acid synthesis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023198864A Division JP2024023388A (ja) 2018-01-24 2023-11-24 オリゴヌクレオチド及び核酸の合成

Publications (4)

Publication Number Publication Date
JP2021510716A JP2021510716A (ja) 2021-04-30
JP2021510716A5 true JP2021510716A5 (https=) 2022-02-24
JPWO2019145713A5 JPWO2019145713A5 (https=) 2022-02-24
JP7493452B2 JP7493452B2 (ja) 2024-05-31

Family

ID=61283585

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020539253A Active JP7493452B2 (ja) 2018-01-24 2019-01-23 オリゴヌクレオチド及び核酸の合成
JP2023198864A Pending JP2024023388A (ja) 2018-01-24 2023-11-24 オリゴヌクレオチド及び核酸の合成

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023198864A Pending JP2024023388A (ja) 2018-01-24 2023-11-24 オリゴヌクレオチド及び核酸の合成

Country Status (11)

Country Link
US (2) US20210047361A1 (https=)
EP (1) EP3743433A1 (https=)
JP (2) JP7493452B2 (https=)
KR (1) KR20200115561A (https=)
CN (1) CN111770928A (https=)
AU (1) AU2019213203B2 (https=)
CA (1) CA3088583A1 (https=)
GB (1) GB201801182D0 (https=)
IL (1) IL276149B (https=)
SG (1) SG11202006741WA (https=)
WO (1) WO2019145713A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11970696B1 (en) 2019-08-27 2024-04-30 Leidos, Inc. Optical methods and systems for DNA assembly for computer data storage
WO2022183121A1 (en) 2021-02-26 2022-09-01 Avery Digital Data, Inc. Semiconductor chip devices and methods for polynucleotide synthesis
CN113004360A (zh) * 2021-03-03 2021-06-22 通用生物系统(安徽)有限公司 一种用于膜杂交检测的氨基修饰引物的生产方法
CN114621307B (zh) * 2022-04-12 2024-12-13 中国科学院苏州生物医学工程技术研究所 一种寡核苷酸空间坐标编码方法及其微流控装置
GB202300626D0 (en) 2023-01-16 2023-03-01 Evonetix Ltd Hybridisation detection
CN116333006A (zh) * 2023-04-07 2023-06-27 苏州欧利生物医药科技有限公司 一种带有荧光标记物的寡核苷酸的固相合成方法
US20250206769A1 (en) 2023-12-22 2025-06-26 Imec Vzw Synthesizing a Nucleic Acid or Nucleic Acid Analogue
WO2025163199A1 (en) 2024-02-01 2025-08-07 Analog Devices International Unlimited Company Methods of amplifying target nucleic acids in a sample
WO2025165064A1 (ko) * 2024-02-02 2025-08-07 에스티팜 주식회사 올리고뉴클레오티드 합성을 위한 개선된 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6270391A (ja) * 1985-09-25 1987-03-31 Nippon Zeon Co Ltd 保護されたオリゴヌクレオチドの製造法
US5419874A (en) * 1992-07-06 1995-05-30 Beckman Instruments, Inc. Synthesis reaction column
US7135565B2 (en) * 2000-07-28 2006-11-14 Agilent Technologies, Inc. Synthesis of polynucleotides using combined oxidation/deprotection chemistry
WO2004101582A2 (en) * 2003-05-09 2004-11-25 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Thermolabile hydroxyl protecting groups and methods of use
US8138330B2 (en) * 2006-09-11 2012-03-20 Sigma-Aldrich Co. Llc Process for the synthesis of oligonucleotides
JP2010248084A (ja) 2009-04-10 2010-11-04 Invitrogen Japan Kk 新規洗浄溶媒を用いるオリゴヌクレオチド合成法

Similar Documents

Publication Publication Date Title
JP2021510716A5 (https=)
AU2021203934B2 (en) Compositions And Methods For Chemical Cleavage And Deprotection Of Surface-Bound Oligonucleotides
US7553958B2 (en) Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports
Caruthers Chemical synthesis of DNA and DNA analogs
JP7493452B2 (ja) オリゴヌクレオチド及び核酸の合成
US20030068643A1 (en) Methods and compositions for economically synthesizing and assembling long DNA sequences
US20030036066A1 (en) Linker phosphoramidites for oligonucleotide synthesis
AU2002305061A1 (en) Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid support
JP2005538725A (ja) 遺伝子長ポリヌクレオチドのマイクロアレイ合成及びそのアセンブリ
JP2005538725A5 (https=)
AU8650991A (en) Synthesis of oligonucleotides
JPH1072486A5 (https=)
JPWO2019145713A5 (https=)
CN117813400A (zh) 引物组和掺入这些引物组的方法和试剂盒
WO2008141799A1 (en) Oligophosphoramidates
CN117480008A (zh) 用于dna合成的电接枝膜
US20090047712A1 (en) Chemically cleavable phosphoramidite linkers