|
ATE298248T1
(de)
|
1998-04-15 |
2005-07-15 |
Brigham & Womens Hospital |
T-zell inhibierende rezeptorzusammensetzungen sowie deren verwendung
|
|
US20040047858A1
(en)
|
2002-09-11 |
2004-03-11 |
Blumberg Richard S. |
Therapeutic anti-BGP(C-CAM1) antibodies and uses thereof
|
|
BRPI0509580A
(pt)
|
2004-03-30 |
2007-11-27 |
Pfizer Prod Inc |
combinações de inibidores de transdução de sinal
|
|
WO2006061712A2
(en)
|
2004-12-10 |
2006-06-15 |
Pfizer Inc. |
Use of mek inhibitors in treating abnormal cell growth
|
|
EP2094682A2
(en)
|
2006-12-22 |
2009-09-02 |
Novartis AG |
Heteroaryl-heteroaryl compounds as cdk inhibitors for the treatment of cancer, inflammation and viral infections
|
|
US9259399B2
(en)
|
2007-11-07 |
2016-02-16 |
Cornell University |
Targeting CDK4 and CDK6 in cancer therapy
|
|
AU2008343932B2
(en)
|
2007-12-19 |
2013-08-15 |
Amgen Inc. |
Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
|
|
ES2622559T3
(es)
|
2008-07-29 |
2017-07-06 |
Nerviano Medical Sciences S.R.L. |
Combinación terapéutica que comprende un inhibidor de cdk y un agente antineoplásico
|
|
AU2009284098B2
(en)
|
2008-08-22 |
2012-03-29 |
Astex Therapeutics Ltd. |
Pyrrolopyrimidine compounds as CDK inhibitors
|
|
WO2010039997A2
(en)
|
2008-10-01 |
2010-04-08 |
The University Of North Carolina At Chapel Hill |
Hematopoietic protection against chemotherapeutic compounds using selective cyclin-dependent kinase 4/6 inhibitors
|
|
AU2009310352A1
(en)
|
2008-10-01 |
2010-05-06 |
The University Of North Carolina At Chapel Hill |
Hematopoietic protection against ionizing radiation using selective cyclin-dependent kinase 4/6 inhibitors
|
|
PA8852901A1
(es)
|
2008-12-22 |
2010-07-27 |
Lilly Co Eli |
Inhibidores de proteina cinasa
|
|
ES2668874T3
(es)
|
2009-04-30 |
2018-05-22 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Anticuerpos anti-CEACAM1 y métodos de uso de los mismos
|
|
EP3025724B1
(en)
|
2009-05-13 |
2018-07-11 |
The University of North Carolina At Chapel Hill |
Cyclin dependent kinase inhibitors and methods of use
|
|
CN102713618B
(zh)
|
2009-09-16 |
2015-07-15 |
新基阿维罗米克斯研究公司 |
蛋白激酶复合物和抑制剂
|
|
US9234192B2
(en)
*
|
2010-02-16 |
2016-01-12 |
Novo Nordisk A/S |
Conjugated proteins
|
|
UY33227A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina como inhibidores de la cdk4/6
|
|
UY33226A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina deuterada como inhibidores de la cdk4/6
|
|
EP3205648A1
(en)
|
2010-06-10 |
2017-08-16 |
Seragon Pharmaceuticals, Inc. |
Estrogen receptor modulators and uses thereof
|
|
US8853423B2
(en)
|
2010-06-17 |
2014-10-07 |
Seragon Pharmaceuticals, Inc. |
Indane estrogen receptor modulators and uses thereof
|
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
|
US8691830B2
(en)
|
2010-10-25 |
2014-04-08 |
G1 Therapeutics, Inc. |
CDK inhibitors
|
|
KR102186969B1
(ko)
|
2010-10-25 |
2020-12-04 |
쥐원 쎄라퓨틱스, 인크. |
Cdk 억제제
|
|
WO2012068381A2
(en)
|
2010-11-17 |
2012-05-24 |
The University Of North Carolina At Chapel Hill |
Protection of renal tissues from schema through inhibition of the proliferative kisses cdk4 and cdk6
|
|
KR101606250B1
(ko)
|
2011-03-23 |
2016-03-24 |
암젠 인크 |
Cdk 4/6 및 flt3의 융합된 트리사이클릭 이중 저해제
|
|
US9271988B2
(en)
|
2011-07-01 |
2016-03-01 |
Novartis Ag |
Combination therapy comprising a CDK4/6 inhibitor and a P13K inhibitor for use in the treatment of cancer
|
|
DK3686193T3
(da)
|
2011-07-27 |
2022-05-30 |
Astrazeneca Ab |
2-(2,4,5-substitueret anilino)pyrimidinforbindelser
|
|
WO2013054320A1
(en)
|
2011-10-11 |
2013-04-18 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
|
|
ES2753614T3
(es)
|
2011-12-01 |
2020-04-13 |
Brigham & Womens Hospital Inc |
Anticuerpos recombinantes anti-CEACAM1 para terapia contra el cáncer
|
|
EP2791132A4
(en)
|
2011-12-14 |
2015-08-05 |
Seragon Pharmaceuticals Inc |
ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
|
|
BR112014014767A2
(pt)
|
2011-12-16 |
2017-06-13 |
Olema Pharmaceuticals Inc |
novos compostos de benzopirano, composições e usos dos mesmos
|
|
EP3216792B1
(en)
|
2012-03-29 |
2020-05-27 |
G1 Therapeutics, Inc. |
Lactam kinase inhibitors
|
|
AR091876A1
(es)
|
2012-07-26 |
2015-03-04 |
Novartis Ag |
Combinaciones farmaceuticas para el tratamiento de enfermedades proliferativas
|
|
JP2015525781A
(ja)
|
2012-07-31 |
2015-09-07 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. |
免疫応答の調節
|
|
CN104145514B
(zh)
|
2012-08-01 |
2018-03-13 |
华为技术有限公司 |
用于同步的方法、装置及系统
|
|
HK1213044A1
(zh)
|
2012-08-03 |
2016-06-24 |
Foundation Medicine, Inc. |
人乳头瘤病毒作为肿瘤预後的预测因子
|
|
DK3431475T3
(da)
|
2013-02-21 |
2021-05-25 |
Pfizer |
Faste former af en selektiv CDK4/6-hæmmer
|
|
JP6430483B2
(ja)
|
2013-03-15 |
2018-11-28 |
ジー1、セラピューティクス、インコーポレイテッドG1 Therapeutics, Inc. |
化学療法の間の正常細胞の一時的な保護
|
|
CA2906157C
(en)
*
|
2013-03-15 |
2022-05-17 |
G1 Therapeutics, Inc. |
Highly active anti-neoplastic and anti-proliferative agents
|
|
WO2014144596A2
(en)
|
2013-03-15 |
2014-09-18 |
G1 Therapeutics, Inc. |
Transient protection of hematopoietic stem and progenitor cells against ionizing radiation
|
|
WO2014203132A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Substituted benzopyran compounds, compositions and uses thereof
|
|
BR112015030595A2
(pt)
|
2013-06-19 |
2017-07-25 |
Seragon Pharmaceuticals Inc |
moduladores de receptor de estrogênio de azetidina e usos dos mesmos
|
|
EA031077B1
(ru)
|
2013-06-19 |
2018-11-30 |
Серагон Фармасьютикалз, Инк. |
Модулятор рецептора эстрогена и его применения
|
|
WO2014203129A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Combinations of benzopyran compounds, compositions and uses thereof
|
|
US20160361314A1
(en)
|
2013-08-28 |
2016-12-15 |
Novartis Ag |
Combination of an alk inhibitor and a cdk inhibitor for the treatment of cell proliferative diseases
|
|
WO2015061407A1
(en)
|
2013-10-24 |
2015-04-30 |
Francis Xavier Tavares |
Process for synthesis of lactams
|
|
US10314842B2
(en)
|
2013-12-02 |
2019-06-11 |
Cornell University |
Methods for treating B cell proliferative disorders
|
|
US11013743B2
(en)
|
2013-12-20 |
2021-05-25 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of CDK and ERK inhibitors
|
|
RU2670762C2
(ru)
|
2013-12-31 |
2018-10-25 |
Хуаньчжу Фарма Ко., Лтд. |
Производные 6-(пиримидиноаминопиридин)бензоимидазола, полезные для лечения рака
|
|
WO2015161283A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use in hspc-sparing treatments for rb-positive abnormal cellular proliferation
|
|
WO2016024232A1
(en)
|
2014-08-11 |
2016-02-18 |
Acerta Pharma B.V. |
Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor and/or a cdk 4/6 inhibitor
|
|
US20170231995A1
(en)
*
|
2014-08-11 |
2017-08-17 |
Acerta Pharma B.V. |
BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
|
|
WO2016025650A1
(en)
|
2014-08-13 |
2016-02-18 |
Celgene Avilomics Research, Inc. |
Combinations of an erk inhibitor and a cdk4/6 inhibitor and related methods
|
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
EP3191126B1
(en)
|
2014-09-13 |
2020-05-13 |
Novartis AG |
Combination therapies of alk inhibitors
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
US20160220569A1
(en)
*
|
2015-02-03 |
2016-08-04 |
G1 Therapeutics, Inc. |
CDK4/6 Inhibitor Dosage Formulations For The Protection Of Hematopoietic Stem And Progenitor Cells During Chemotherapy
|
|
CN106065016B
(zh)
|
2015-04-22 |
2019-03-12 |
江苏恒瑞医药股份有限公司 |
一种周期素依赖性蛋白激酶抑制剂的结晶形式及其制备方法
|
|
US20180243304A1
(en)
|
2015-08-28 |
2018-08-30 |
Novartis Ag |
Pharmaceutical combinations comprising (a) the cyclin dependent kinase 4/6 (cdk4/6) inhibitor lee011 (=ribociclib), and (b) the epidermal growth factor receptor (egfr) inhibitor erlotinib, for the treatment or prevention of cancer
|
|
WO2017160568A1
(en)
|
2016-03-16 |
2017-09-21 |
Eli Lilly And Company |
Combination therapy comprising the cdk4/6 inhibitor necitumumab and the egfr inhibitor abemaciclib for use in treating cancer
|
|
WO2017193141A1
(en)
|
2016-05-06 |
2017-11-09 |
Siyuan Zhang |
Prognosis biomarkers and anti-tumor compositions of targeted therapeutic treatments for triple negative breast cancer
|
|
WO2017223115A1
(en)
|
2016-06-22 |
2017-12-28 |
Radius Health, Inc. |
Ar+ breast cancer treatment methods
|
|
BR112019003722A2
(pt)
|
2016-08-23 |
2019-05-28 |
Eisai R&D Man Co Ltd |
terapias de combinação para o tratamento de carcinoma hepatocelular
|
|
US11865176B2
(en)
|
2016-11-08 |
2024-01-09 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of modulating anti-tumor immunity
|
|
EP3541389A1
(en)
|
2016-11-16 |
2019-09-25 |
Pfizer Inc |
Combination of an egfr t790m inhibitor and a cdk inhibitor for the treatment of non-small cell lung cancer
|
|
IL317919A
(en)
|
2016-12-05 |
2025-02-01 |
G1 Therapeutics Inc |
Preservation of immune response during chemotherapy regimens
|
|
EP3585389A4
(en)
|
2017-02-22 |
2020-12-23 |
G1 Therapeutics, Inc. |
EGFR-CAUSED CANCER TREATMENT WITH LESS SIDE EFFECTS
|
|
WO2018170447A1
(en)
|
2017-03-16 |
2018-09-20 |
Eisai R&D Management Co., Ltd. |
Combination therapies for the treatment of breast cancer
|
|
WO2018183479A1
(en)
|
2017-03-30 |
2018-10-04 |
Dana-Farber Cancer Institute, Inc. |
Methods for modulating regulatory t cells and immune responses using cdk4/6 inhibitors
|
|
WO2018218633A1
(en)
|
2017-06-02 |
2018-12-06 |
Beijing Percans Oncology Co. Ltd. |
Combination therapies for treating cancers
|
|
CA3067023A1
(en)
|
2017-06-12 |
2018-12-20 |
Syros Pharmaceuticals, Inc. |
Compositions and methods for treating cancers with covalent inhibitors of cyclin-dependent kinase 7 (cdk7)
|
|
GB201709417D0
(en)
|
2017-06-14 |
2017-07-26 |
Inst Of Cancer Research: Royal Cancer Hospital |
Cyclin dependent kinase 4/6 inhibitors for use in methods of treating cancer
|
|
TW201904574A
(zh)
|
2017-06-21 |
2019-02-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
SERD與CDK4/6抑制劑、PI3K/mTOR通路抑制劑的用途
|
|
CA3066778A1
(en)
|
2017-06-21 |
2018-12-27 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
|
EP3645001B1
(en)
*
|
2017-06-29 |
2024-07-03 |
G1 Therapeutics, Inc. |
Morphic forms of git38 and methods of manufacture thereof
|
|
EP3661519A1
(en)
|
2017-08-03 |
2020-06-10 |
Novartis AG |
Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor
|
|
US20200377599A1
(en)
|
2017-11-30 |
2020-12-03 |
Beth Israel Deaconess Medical Center, Inc. |
Compositions and methods for treating cancer
|
|
WO2019136451A1
(en)
*
|
2018-01-08 |
2019-07-11 |
G1 Therapeutics, Inc. |
G1t38 superior dosage regimes
|