JP2021505620A5 - - Google Patents

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JP2021505620A5
JP2021505620A5 JP2020531164A JP2020531164A JP2021505620A5 JP 2021505620 A5 JP2021505620 A5 JP 2021505620A5 JP 2020531164 A JP2020531164 A JP 2020531164A JP 2020531164 A JP2020531164 A JP 2020531164A JP 2021505620 A5 JP2021505620 A5 JP 2021505620A5
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JP
Japan
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arginase
human
subject
use according
administered
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JP2020531164A
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English (en)
Japanese (ja)
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JP2021505620A (ja
JP7827407B2 (ja
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Priority claimed from PCT/US2018/063982 external-priority patent/WO2019113157A1/en
Publication of JP2021505620A publication Critical patent/JP2021505620A/ja
Publication of JP2021505620A5 publication Critical patent/JP2021505620A5/ja
Priority to JP2023199616A priority Critical patent/JP2024028760A/ja
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Publication of JP7827407B2 publication Critical patent/JP7827407B2/ja
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JP2020531164A 2017-12-05 2018-12-05 アルギナーゼ1欠損症を治療するための方法及び組成物 Active JP7827407B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023199616A JP2024028760A (ja) 2017-12-05 2023-11-27 アルギナーゼ1欠損症を治療するための方法及び組成物

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762594747P 2017-12-05 2017-12-05
US62/594,747 2017-12-05
US201862725612P 2018-08-31 2018-08-31
US62/725,612 2018-08-31
US201862745000P 2018-10-12 2018-10-12
US62/745,000 2018-10-12
PCT/US2018/063982 WO2019113157A1 (en) 2017-12-05 2018-12-05 Method and composition for treating arginase 1 deficiency

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023199616A Division JP2024028760A (ja) 2017-12-05 2023-11-27 アルギナーゼ1欠損症を治療するための方法及び組成物

Publications (3)

Publication Number Publication Date
JP2021505620A JP2021505620A (ja) 2021-02-18
JP2021505620A5 true JP2021505620A5 (enExample) 2022-01-11
JP7827407B2 JP7827407B2 (ja) 2026-03-10

Family

ID=64734275

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020531164A Active JP7827407B2 (ja) 2017-12-05 2018-12-05 アルギナーゼ1欠損症を治療するための方法及び組成物
JP2023199616A Pending JP2024028760A (ja) 2017-12-05 2023-11-27 アルギナーゼ1欠損症を治療するための方法及び組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023199616A Pending JP2024028760A (ja) 2017-12-05 2023-11-27 アルギナーゼ1欠損症を治療するための方法及び組成物

Country Status (10)

Country Link
US (2) US11717562B2 (enExample)
EP (1) EP3720476A1 (enExample)
JP (2) JP7827407B2 (enExample)
KR (1) KR20200122298A (enExample)
CN (3) CN111787941A (enExample)
AU (1) AU2018378485B2 (enExample)
CA (1) CA3084801A1 (enExample)
MX (2) MX2020005933A (enExample)
TW (1) TWI878212B (enExample)
WO (1) WO2019113157A1 (enExample)

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Publication number Priority date Publication date Assignee Title
EP3449935A1 (en) * 2017-08-31 2019-03-06 Erytech Pharma Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
CA3116736A1 (en) 2018-10-19 2020-04-23 Aerase, Inc. Arginine depletion therapy for treatment of gamt deficiency
US20210189371A1 (en) * 2019-08-30 2021-06-24 Aeglea Biotherapeutics, Inc. Methods For Production Of Human Recombinant Arginase 1 And Uses Thereof
CN114214353B (zh) * 2021-11-30 2023-07-18 新泰市佳禾生物科技有限公司 一种发酵生产人重组精氨酸酶i的方法
CN114350721B (zh) * 2021-11-30 2024-05-24 新泰市佳禾生物科技有限公司 微生物酶法生产l-鸟氨酸的方法
CN114196712B (zh) * 2021-11-30 2024-04-02 新泰市佳禾生物科技有限公司 一种固定化酶法生产l-鸟氨酸的方法
CN116179452A (zh) * 2022-07-11 2023-05-30 山东第一医科大学(山东省医学科学院) 一种用于治疗精氨酸酶缺乏症的工程益生菌及其构建方法和应用
WO2025171346A1 (en) * 2024-02-08 2025-08-14 University Of Florida Research Foundation, Incorporated Indoleamine 2,3-dioxygenase variants

Family Cites Families (22)

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JPH02117383A (ja) 1988-10-26 1990-05-01 Tosoh Corp ヒトアルギナーゼの製造方法
US5780286A (en) 1996-03-14 1998-07-14 Smithkline Beecham Corporation Arginase II
AU2003216109A1 (en) 2002-01-25 2003-09-02 Cancer Treatments International Therapeutic composition for treatment of cancer by arginine depletion
HK1053577A2 (en) 2002-06-20 2003-10-10 Bio-Cancer Treatment International Limited Pharmaceutical composition and method of treatment of human malignanices with arginine deprivation
GB0315248D0 (en) * 2003-06-30 2003-08-06 Hoffmann La Roche HCV regulated protein expression
FR2873925B1 (fr) 2004-08-05 2006-10-13 Erytech Pharma Soc Par Actions Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes
CN1745847A (zh) 2004-09-08 2006-03-15 康达医药科技有限公司 用精氨酸酶治疗肝炎的药物组合物和方法
DE602006019916D1 (de) 2005-12-12 2011-03-10 Canji Inc Adenovirale expressionsvektoren mit einer expressionskassette im e1-bereich und einer inaktivierten e2b-polymerase
SI3778885T1 (sl) 2008-10-31 2023-07-31 Aerase, Inc. Sestavki inženirskih humanih arginaz in metode za zdravljenje raka
US9382525B2 (en) * 2009-03-26 2016-07-05 The Hong Kong Polytechnic University Site-directed pegylation of arginases and the use thereof as anti-cancer and anti-viral agents
JP2012531893A (ja) 2009-06-29 2012-12-13 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム アルギナーゼ製剤および方法
WO2012061015A2 (en) 2010-11-03 2012-05-10 Scott & White Healthcare L-citrulline supplementation during arginine depletion therapy with arginase
CN103184209B (zh) * 2011-12-27 2015-09-16 拜奥生物科技(上海)有限公司 人精氨酸酶和聚乙二醇化人精氨酸酶及其应用
WO2014093694A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Crispr-cas nickase systems, methods and compositions for sequence manipulation in eukaryotes
FR3005420B1 (fr) 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
DE212015000061U1 (de) 2014-02-11 2017-09-03 The Regents Of The University Of Colorado, A Body Corporate CRISPR-ermöglichtes Multiplex Genom Engineering
CA2944903A1 (en) 2014-04-24 2015-10-29 Dana-Farber Cancer Institute, Inc. Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response
CN113144178B (zh) * 2014-04-29 2024-10-18 康达医药科技有限公司 采用精氨酸酶i调节免疫系统的方法和组合物
EP2982758A1 (en) 2014-08-04 2016-02-10 Centre Hospitalier Universitaire Vaudois (CHUV) Genome editing for the treatment of huntington's disease
HUE043847T2 (hu) 2014-08-28 2019-09-30 Halozyme Inc Hialuronán-lebontó enzimmel és egy immun checkpoint inhibitorral végzett kombinációs terápia
EP3416976A2 (en) 2016-02-16 2018-12-26 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
WO2017192449A1 (en) 2016-05-06 2017-11-09 Phasebio Pharmaceuticals, Inc. Elp fusion proteins for controlled and sustained release

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